BRPI0309631A2 - vacina tetravalente da dengue contendo uma trivial deleção de 30 nucleotídeos na utr-31' dos tipos de dengue 1,2,3,e 4, ou de vírus antigênicos quiméricos da dengue 1,2,3 e 4 - Google Patents

vacina tetravalente da dengue contendo uma trivial deleção de 30 nucleotídeos na utr-31' dos tipos de dengue 1,2,3,e 4, ou de vírus antigênicos quiméricos da dengue 1,2,3 e 4

Info

Publication number
BRPI0309631A2
BRPI0309631A2 BRPI0309631A BRPI0309631A BRPI0309631A2 BR PI0309631 A2 BRPI0309631 A2 BR PI0309631A2 BR PI0309631 A BRPI0309631 A BR PI0309631A BR PI0309631 A BRPI0309631 A BR PI0309631A BR PI0309631 A2 BRPI0309631 A2 BR PI0309631A2
Authority
BR
Brazil
Prior art keywords
dengue
utr
trivial
nucleotides
deletion
Prior art date
Application number
BRPI0309631A
Other languages
English (en)
Inventor
Barry Falgout
Joseph Blaney
Kathryn Hanley
Lewis Markoff
Stephen S Whitehead
Original Assignee
Government Of The United Of America As Represented By The Secretary Of The Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Government Of The United Of America As Represented By The Secretary Of The Health And Human Services filed Critical Government Of The United Of America As Represented By The Secretary Of The Health And Human Services
Publication of BRPI0309631A2 publication Critical patent/BRPI0309631A2/pt
Publication of BRPI0309631A8 publication Critical patent/BRPI0309631A8/pt
Publication of BRPI0309631B1 publication Critical patent/BRPI0309631B1/pt

Links

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BRPI0309631-9A 2002-05-03 2003-04-25 Composição imunogênica tetravalente compreendendo vírus atenuado contra dengue e vacina tetravalente compreendendo a dita composição BRPI0309631B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37786002P 2002-05-03 2002-05-03
US60/377,860 2002-05-03
US43650002P 2002-12-23 2002-12-23
US60/436,500 2002-12-23
PCT/US2003/013279 WO2003092592A2 (en) 2002-05-03 2003-04-25 Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3'-utr of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4

Publications (3)

Publication Number Publication Date
BRPI0309631A2 true BRPI0309631A2 (pt) 2016-11-01
BRPI0309631A8 BRPI0309631A8 (pt) 2018-09-25
BRPI0309631B1 BRPI0309631B1 (pt) 2021-07-20

Family

ID=29406814

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0309631-9A BRPI0309631B1 (pt) 2002-05-03 2003-04-25 Composição imunogênica tetravalente compreendendo vírus atenuado contra dengue e vacina tetravalente compreendendo a dita composição

Country Status (15)

Country Link
US (7) US7517531B2 (pt)
EP (5) EP3763382A1 (pt)
JP (1) JP4977811B2 (pt)
AT (1) ATE481982T1 (pt)
BR (1) BRPI0309631B1 (pt)
CA (1) CA2483653C (pt)
CY (1) CY1120558T1 (pt)
DE (1) DE60334310D1 (pt)
DK (2) DK1554301T3 (pt)
ES (2) ES2677348T3 (pt)
HU (1) HUE037330T2 (pt)
PT (2) PT1554301E (pt)
SI (2) SI1554301T1 (pt)
TR (1) TR201806655T4 (pt)
WO (1) WO2003092592A2 (pt)

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JP4549224B2 (ja) * 2005-04-25 2010-09-22 出光ユニテック株式会社 透明ポリプロピレン系樹脂シートの製造方法、透明ポリプロピレン系樹脂シート、及び成形品、並びに透明ポリプロピレン系樹脂シートからなる成形品の白化防止方法、及び温度判別方法
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KR101857249B1 (ko) 2011-05-27 2018-05-14 삼성디스플레이 주식회사 패터닝 슬릿 시트 어셈블리, 유기막 증착 장치, 유기 발광 표시장치제조 방법 및 유기 발광 표시 장치
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EP1554301B1 (en) 2010-09-22
AU2003231185A1 (en) 2003-11-17
US11753627B2 (en) 2023-09-12
EP1554301A4 (en) 2006-11-08
DK1554301T3 (da) 2011-01-24
EP2338508B1 (en) 2018-02-14
CY1120558T1 (el) 2019-07-10
DK2338508T3 (en) 2018-05-28
BRPI0309631A8 (pt) 2018-09-25
WO2003092592A3 (en) 2005-05-19
ATE481982T1 (de) 2010-10-15
BRPI0309631B1 (pt) 2021-07-20
EP3763382A1 (en) 2021-01-13
DE60334310D1 (de) 2010-11-04
TR201806655T4 (tr) 2018-06-21
WO2003092592A2 (en) 2003-11-13
US10837003B2 (en) 2020-11-17
EP2319532A1 (en) 2011-05-11
CA2483653A1 (en) 2003-11-13
PT2338508T (pt) 2018-05-16
US20180010099A1 (en) 2018-01-11
EP2338508A1 (en) 2011-06-29
EP1554301A2 (en) 2005-07-20
SI1554301T1 (sl) 2011-01-31
PT1554301E (pt) 2010-12-28
US20070009552A1 (en) 2007-01-11
US20200392469A1 (en) 2020-12-17
EP3205352A1 (en) 2017-08-16
US7517531B2 (en) 2009-04-14
US20090258036A1 (en) 2009-10-15
JP2005532044A (ja) 2005-10-27
USRE46641E1 (en) 2017-12-19
US20130011433A1 (en) 2013-01-10
ES2677348T3 (es) 2018-08-01
US9783787B2 (en) 2017-10-10
CA2483653C (en) 2014-10-28
SI2338508T1 (en) 2018-07-31
HUE037330T2 (hu) 2018-08-28
USRE46631E1 (en) 2017-12-12
US8075903B2 (en) 2011-12-13
JP4977811B2 (ja) 2012-07-18
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