BR9915927A - Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis - Google Patents

Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis

Info

Publication number
BR9915927A
BR9915927A BR9915927-9A BR9915927A BR9915927A BR 9915927 A BR9915927 A BR 9915927A BR 9915927 A BR9915927 A BR 9915927A BR 9915927 A BR9915927 A BR 9915927A
Authority
BR
Brazil
Prior art keywords
esters
physiologically compatible
compatible salts
ibandronic acid
acid
Prior art date
Application number
BR9915927-9A
Other languages
English (en)
Inventor
Frieder Bauss
Andreas A Kurth
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of BR9915927A publication Critical patent/BR9915927A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

<B><MU>USO DE áCIDO IBANDRÈNICO OU SEUS SAIS OU éSTERES FISIOLOGICAMENTE COMPATìVEIS<MV><D> A invenção refere-se ao uso de ácido ibandrónico (ácido 1-hidróxi-3-(N-metil-N-pentil)aminopropil-1,1-difosfónico) ou seus sais ou ésteres fisiologicamente compatíveis, para aperfeiçoar a osseintegração de endopróteses amarradas isentas de cimento. O ibandronato ou os seus sais são aplicados durante um curto período imediatamente após a inserção de uma endoprótese, com o resultado surpreendente de que se obtém estabilidade secundária do implante em apenas 5 semanas ou menos depois da operação.
BR9915927-9A 1998-12-04 1999-11-29 Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis BR9915927A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19855976 1998-12-04
PCT/EP1999/009252 WO2000033849A1 (en) 1998-12-04 1999-11-29 Use of ibandronate for promoting osseointegration of endoprostheses

Publications (1)

Publication Number Publication Date
BR9915927A true BR9915927A (pt) 2001-08-21

Family

ID=7889968

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915927-9A BR9915927A (pt) 1998-12-04 1999-11-29 Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis

Country Status (17)

Country Link
US (1) US6680307B1 (pt)
EP (2) EP1614422A3 (pt)
JP (1) JP3793023B2 (pt)
KR (1) KR100453779B1 (pt)
CN (1) CN1173704C (pt)
AR (1) AR020017A1 (pt)
AT (1) ATE303153T1 (pt)
AU (1) AU756540B2 (pt)
BR (1) BR9915927A (pt)
CA (1) CA2353528C (pt)
DE (1) DE69927048T2 (pt)
DK (1) DK1135140T3 (pt)
ES (1) ES2247842T3 (pt)
PT (1) PT1135140E (pt)
TR (1) TR200101546T2 (pt)
WO (1) WO2000033849A1 (pt)
ZA (1) ZA200104140B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004038A1 (en) * 2000-07-12 2002-01-17 Hopital Orthopedique De La Suisse Romande Active biocoating for bone implant
EP1228761A3 (en) * 2001-02-01 2003-01-15 Riderway Corporation Liquid pharmaceutical composition for treating bone diseases
CN100479823C (zh) * 2001-12-21 2009-04-22 宝洁公司 双膦酸盐在制造药物套盒中的用途以及用于增加骨质的套盒
ES2532393T3 (es) * 2002-05-10 2015-03-26 F. Hoffmann-La Roche Ag Acidos bisfosfónicos para tratamiento y prevención de osteoporosis
NZ536273A (en) * 2002-12-20 2007-08-31 Hoffmann La Roche High dose ibandronate formulation
EP1508343B1 (en) * 2003-08-21 2015-11-04 AddBIO AB Bisphosponate coated implant device and method therefor
RU2387661C2 (ru) * 2005-02-01 2010-04-27 Ф.Хоффманн-Ля Рош Аг Полиморфная модификация в ибандроната
CA2594802C (en) * 2005-02-01 2012-11-27 Uwe Eiermann Ibandronate polymorph a
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623397A1 (de) 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
CA2151240A1 (en) * 1992-12-23 1994-07-07 Donna T. Whiteford Biophosphonate/estrogen therapy for treating and preventing bone loss
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
FI92465C (fi) 1993-04-14 1994-11-25 Risto Tapani Lehtinen Menetelmä endo-osteaalisten materiaalien käsittelemiseksi
US5646134A (en) 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
GB9408775D0 (en) 1994-05-04 1994-06-22 Ciba Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
WO1996039107A1 (en) * 1995-06-06 1996-12-12 Merck & Co., Inc. Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
JP4269015B2 (ja) * 1996-12-13 2009-05-27 オステオスクリーン アイピー， エルエルシー 骨の成長を刺激する組成物および方法

Also Published As

Publication number Publication date
ATE303153T1 (de) 2005-09-15
EP1135140A1 (en) 2001-09-26
CA2353528A1 (en) 2000-06-15
DE69927048T2 (de) 2006-06-08
US6680307B1 (en) 2004-01-20
JP2002531509A (ja) 2002-09-24
KR20010093137A (ko) 2001-10-27
AU1557700A (en) 2000-06-26
EP1135140B1 (en) 2005-08-31
EP1614422A2 (en) 2006-01-11
ES2247842T3 (es) 2006-03-01
ZA200104140B (en) 2002-08-21
DK1135140T3 (da) 2005-12-19
WO2000033849A1 (en) 2000-06-15
CN1329495A (zh) 2002-01-02
KR100453779B1 (ko) 2004-10-20
DE69927048D1 (de) 2005-10-06
AR020017A1 (es) 2002-03-27
JP3793023B2 (ja) 2006-07-05
EP1614422A3 (en) 2009-02-18
PT1135140E (pt) 2005-10-31
AU756540B2 (en) 2003-01-16
CN1173704C (zh) 2004-11-03
TR200101546T2 (tr) 2001-11-21
CA2353528C (en) 2007-04-24

Similar Documents

Publication Publication Date Title
BR9915927A (pt) Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis
FR2692475B1 (fr) Prothese totale du genou.
ATE328851T1 (de) Magnesium-ammonium-phosphat-zemente, deren herstellung und verwendung
AU4950099A (en) Material for bone reconstruction
MXPA02004591A (es) Cemento hidraulico brushita estabilizado con una sal de magnesio.
ATE27096T1 (de) Femorale hueftgelenkprothese.
DK0679097T3 (da) TGF-Beta-præparat til fremkaldelse af knoglevækst
ATE167044T1 (de) Modulare hüftprothese
IS4100A (is) Aðferð við meðhöndlun á ígræðlingi úr málmi fyrirskurðaðgerð
SE9702981D0 (sv) Dental implant systems
HK1064303A1 (pt)
AU7143898A (en) Trap-coated bone grafts and prostheses
BR9808357A (pt) se projetando para dentro a partir da parede anterior (36).
SE7906537L (sv) Larbenskomponent tillhorande en hoftendoprotes
WO2001064143A3 (en) Shrouds for implants
NO881542D0 (no) Kondisjoneringsvaesker av tann- eller benstoff.
ES2172600T3 (es) Composicion farmaceutica que comprende lamotrigina.
ES2172947T3 (es) Procedimiento de preparacion de composiciones de hidroxiapatito carbonatado.
NO994395L (no) Stabilt, fast preparat som inneholder vitamin D3 og trikalsiumfosfat
FR2703583B1 (fr) Implant femoral pour prothese de hanche.
DE50013752D1 (de) Aufbau einer prothetischen suprakonstruktion
PL361732A1 (en) Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy
ES2085386T3 (es) Procedimiento para la preparacion de tacs cristalino.
DE69927392D1 (de) Zahnprothesehaftmittel
ES2081127T3 (es) Composiciones de acido fluorhidrico.

Legal Events

Date Code Title Description
B65X Notification of requirement for priority examination of patent application
B65Y Grant of priority examination of the patent application (request complies with dec. 132/06 of 20061117)
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AOS ARTIGOS 8O E 11 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]