BR9912299A - Biphenyl derivatives - Google Patents
Biphenyl derivativesInfo
- Publication number
- BR9912299A BR9912299A BR9912299-5A BR9912299A BR9912299A BR 9912299 A BR9912299 A BR 9912299A BR 9912299 A BR9912299 A BR 9912299A BR 9912299 A BR9912299 A BR 9912299A
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- biphenyl derivatives
- deserotonin
- debiphenyl
- byphenyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pregnancy & Childbirth (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: "DERIVADOS DE BIFENILA". Derivados debifenila da fórmula (I) onde R, X, Y, A^ 1^,A^ 2^, A^ 3^, Q e n sãoconforme definidos na reivindicação 1 e seus sais são ativos nosistema nervoso central mostrando propriedades antagonísticas deserotonina.Invention Patent: "BYPHENYL DERIVATIVES". Debiphenyl derivatives of formula (I) where R, X, Y, A ^ 1 ^, A ^ 2 ^, A ^ 3 ^, Q and n are as defined in claim 1 and their salts are active in the central nervous system showing antagonistic deserotonin properties.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98113488 | 1998-07-20 | ||
PCT/EP1999/004803 WO2000005225A1 (en) | 1998-07-20 | 1999-07-08 | Biphenyl derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9912299A true BR9912299A (en) | 2001-11-20 |
Family
ID=8232308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9912299-5A BR9912299A (en) | 1998-07-20 | 1999-07-08 | Biphenyl derivatives |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1098892A1 (en) |
JP (1) | JP2002521377A (en) |
KR (1) | KR20010070997A (en) |
CN (1) | CN1309654A (en) |
AR (1) | AR019415A1 (en) |
AU (1) | AU5033899A (en) |
BR (1) | BR9912299A (en) |
CA (1) | CA2338209A1 (en) |
HU (1) | HUP0102622A3 (en) |
ID (1) | ID27846A (en) |
NO (1) | NO20010333D0 (en) |
PL (1) | PL345283A1 (en) |
SK (1) | SK492001A3 (en) |
WO (1) | WO2000005225A1 (en) |
ZA (1) | ZA200101379B (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1502702A (en) * | 2000-11-14 | 2002-05-27 | Merck Patent Gmbh | Novel uses of combined 5-HT<sub>1A</sub> agonists and serotonin reuptake inhibitors |
CA2432642A1 (en) | 2000-12-21 | 2002-08-08 | Subhash P. Khanapure | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
CA2443724C (en) | 2001-05-11 | 2009-11-03 | Patrizia Caldirola | Novel, arylsusfonamide compounds for the treatment of obesity, type ii diabetes and cns-disorders |
US7718650B2 (en) | 2001-05-11 | 2010-05-18 | Biovitrum Ab | Aryl sulfonamide compounds for treating obesity |
WO2003024448A2 (en) | 2001-09-14 | 2003-03-27 | Methylgene, Inc. | Inhibitors of histone deacetylase |
SE0103644D0 (en) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic isoquinoline compounds |
RU2007107349A (en) | 2004-07-28 | 2008-09-10 | Глэксо Груп Лимитед (GB) | PIPERAZINE DERIVATIVES, APPLICATION FOR TREATMENT OF GASTROINTESTINAL DISORDERS |
WO2006040182A1 (en) * | 2004-10-14 | 2006-04-20 | Abbott Gmbh & Co. Kg | Heterocyclic compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor |
WO2007077457A2 (en) * | 2006-01-06 | 2007-07-12 | The Royal Veterinary College | Treatment of equine laminitis with 5-ht1b/ 1d antagonists |
PE20080176A1 (en) | 2006-03-31 | 2008-04-25 | Glaxo Group Ltd | ARILPIPERAZINE SULFONAMIDE COMPOUNDS AS AGONIST OF GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTORS |
US8642642B2 (en) * | 2006-04-19 | 2014-02-04 | Abbott Laboratories | Heterocyclic arylsulphones suitable for treating disorders that respond to modulation of the serotonin 5HT6 receptor |
TW200808762A (en) | 2006-04-19 | 2008-02-16 | Abbott Gmbh & Co Kg | Heterocyclic compounds suitable for treating disorders that respond to modulation of the serotonin 5HT6 receptor |
MX2008014743A (en) | 2006-05-19 | 2008-12-01 | Wyeth Corp | N-benzoyl-and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists. |
US8507469B2 (en) | 2007-03-23 | 2013-08-13 | Abbott Gmbh & Co. Kg | Azetidin compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor |
EP2155671B8 (en) | 2007-06-05 | 2018-02-21 | Integrative Research Laboratories Sweden AB | Disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission |
PE20090362A1 (en) | 2007-06-08 | 2009-04-04 | Janssen Pharmaceutica Nv | PIPERIDINE / PIPERAZINE DERIVATIVES AS DGAT MODULATORS |
JP5443342B2 (en) | 2007-06-08 | 2014-03-19 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Piperidine / piperazine derivatives |
JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine/Piperazine derivatives |
WO2008148851A1 (en) | 2007-06-08 | 2008-12-11 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
WO2009147170A2 (en) | 2008-06-05 | 2009-12-10 | Janssen Pharmaceutica Nv | Drug combinations comprising a dgat inhibitor and a ppar-agonist |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2162792T3 (en) * | 1991-09-18 | 2002-01-16 | Glaxo Group Ltd | BENZANILIDE DERIVATIVES AS 5-HT1D ANTAGONISTS. |
GB9119920D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
GB2273930A (en) * | 1992-12-30 | 1994-07-06 | Glaxo Group Ltd | Benzanilide derivatives |
GB9507203D0 (en) * | 1995-04-07 | 1995-05-31 | Smithkline Beecham Plc | Novel compounds |
-
1999
- 1999-07-08 KR KR1020017000849A patent/KR20010070997A/en not_active Application Discontinuation
- 1999-07-08 HU HU0102622A patent/HUP0102622A3/en unknown
- 1999-07-08 PL PL99345283A patent/PL345283A1/en unknown
- 1999-07-08 WO PCT/EP1999/004803 patent/WO2000005225A1/en not_active Application Discontinuation
- 1999-07-08 JP JP2000561181A patent/JP2002521377A/en active Pending
- 1999-07-08 ID IDW20010307A patent/ID27846A/en unknown
- 1999-07-08 BR BR9912299-5A patent/BR9912299A/en not_active Application Discontinuation
- 1999-07-08 CN CN99808739A patent/CN1309654A/en active Pending
- 1999-07-08 EP EP99934632A patent/EP1098892A1/en not_active Withdrawn
- 1999-07-08 AU AU50338/99A patent/AU5033899A/en not_active Abandoned
- 1999-07-08 CA CA002338209A patent/CA2338209A1/en not_active Abandoned
- 1999-07-08 SK SK49-2001A patent/SK492001A3/en unknown
- 1999-07-16 AR ARP990103510A patent/AR019415A1/en not_active Application Discontinuation
-
2001
- 2001-01-19 NO NO20010333A patent/NO20010333D0/en unknown
- 2001-02-19 ZA ZA200101379A patent/ZA200101379B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1309654A (en) | 2001-08-22 |
AU5033899A (en) | 2000-02-14 |
PL345283A1 (en) | 2001-12-03 |
SK492001A3 (en) | 2001-08-06 |
WO2000005225A1 (en) | 2000-02-03 |
EP1098892A1 (en) | 2001-05-16 |
NO20010333L (en) | 2001-01-19 |
AR019415A1 (en) | 2002-02-20 |
JP2002521377A (en) | 2002-07-16 |
HUP0102622A3 (en) | 2002-12-28 |
HUP0102622A2 (en) | 2001-12-28 |
CA2338209A1 (en) | 2000-02-03 |
NO20010333D0 (en) | 2001-01-19 |
ID27846A (en) | 2001-04-26 |
KR20010070997A (en) | 2001-07-28 |
ZA200101379B (en) | 2002-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |