BR9911981A - Esparadrapo tópico com anti-reumático não esteroidal com grupo ácido - Google Patents

Esparadrapo tópico com anti-reumático não esteroidal com grupo ácido

Info

Publication number
BR9911981A
BR9911981A BR9911981-1A BR9911981A BR9911981A BR 9911981 A BR9911981 A BR 9911981A BR 9911981 A BR9911981 A BR 9911981A BR 9911981 A BR9911981 A BR 9911981A
Authority
BR
Brazil
Prior art keywords
active substance
adhesive
acid group
steroidal
matrix
Prior art date
Application number
BR9911981-1A
Other languages
English (en)
Other versions
BR9911981B1 (pt
Inventor
Walter Mueller
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BR9911981A publication Critical patent/BR9911981A/pt
Publication of BR9911981B1 publication Critical patent/BR9911981B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"ESPARADRAPO TóPICO COM ANTI-REUMáTICO NãO ESTEROIDAL COM GRUPO áCIDO"<D>. Um esparadrapo tópico com anti-reumático não esteroidal como substância ativa, constituído de uma camada reversa inerte comparada com a substância ativa, de uma camada matriz contendo substância ativa, autoadesiva à base de um glúten de poliacrilato e de uma película protetora a ser removida antes do uso, é caracterizado pelo fato de que a. o anti-reumático não esteroidal dispõe de um grupo carboxila livre, b. a matriz do esparadrapo contendo substância ativa se constitui de um glúten de poliacrilato reticulado com íons de metais polivalentes, dispondo de grupos carboxila livres e é isento de grupos hidroxila, c. a matriz contém um ácido graxo como plastificante e aceleradores de permeação e d. a camada reversa constitui-se de um material têxtil, elástico em pelo menos uma direção.
BRPI9911981-1A 1998-07-09 1999-07-06 esparadrapo tópico com anti-reumático não esteroidal com grupo ácido. BR9911981B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19830649A DE19830649C2 (de) 1998-07-09 1998-07-09 Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe
PCT/EP1999/004686 WO2000002539A1 (de) 1998-07-09 1999-07-06 Topisches pflaster mit nichtsteroidalen antirheumatika mit säuregruppe

Publications (2)

Publication Number Publication Date
BR9911981A true BR9911981A (pt) 2001-03-27
BR9911981B1 BR9911981B1 (pt) 2010-06-01

Family

ID=7873428

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9911981-1A BR9911981B1 (pt) 1998-07-09 1999-07-06 esparadrapo tópico com anti-reumático não esteroidal com grupo ácido.

Country Status (23)

Country Link
US (1) US6676962B1 (pt)
EP (1) EP1094796B1 (pt)
JP (1) JP2002520270A (pt)
KR (1) KR100549847B1 (pt)
CN (1) CN1222280C (pt)
AR (1) AR019343A1 (pt)
AT (1) ATE251900T1 (pt)
AU (1) AU750861B2 (pt)
BR (1) BR9911981B1 (pt)
CA (1) CA2336732C (pt)
CZ (1) CZ290992B6 (pt)
DE (2) DE19830649C2 (pt)
ES (1) ES2212584T3 (pt)
HU (1) HU227839B1 (pt)
IL (2) IL140744A0 (pt)
MX (1) MXPA01000128A (pt)
NZ (1) NZ509216A (pt)
PL (1) PL192009B1 (pt)
RU (1) RU2212232C2 (pt)
TR (1) TR200100022T2 (pt)
TW (1) TW577760B (pt)
WO (1) WO2000002539A1 (pt)
ZA (1) ZA200100172B (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
DE10003767A1 (de) * 2000-01-28 2001-10-04 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung nichtsteroidaler Antirheumatika
CA2397224A1 (en) * 2000-02-03 2001-08-09 Tissuemed Limited Device for the closure of a surgical puncture
US7727547B2 (en) * 2000-04-04 2010-06-01 Tissuemed Limited Tissue-adhesive formulations
US6455067B1 (en) * 2000-05-24 2002-09-24 Sang-A Pharmaceutical Co., Ltd. Transdermal patch for nonsteroidal antiinflammatory drug(s)
DE10032537A1 (de) * 2000-07-05 2002-01-31 Labtec Gmbh Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure
DE10049225A1 (de) * 2000-09-28 2002-04-11 Labtec Gmbh Dermales System, enthaltend Diclofenac
ATE286408T1 (de) * 2000-10-23 2005-01-15 Tissuemed Ltd Selbstklebende, hydratierbare matrix für therapeutische anwendungen
DE10103860B4 (de) * 2001-01-30 2004-12-23 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung
BR0215068A (pt) * 2001-12-21 2004-11-09 Coloplast As Dispositivo para cuidar de feridas
CA2526751A1 (en) * 2003-06-19 2004-12-23 Coloplast A/S A wound care device
EP1732577B1 (en) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topical delivery of l-arginine to improve body and skin appearance
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
CA2563678A1 (en) 2004-04-19 2005-11-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
MX2007001554A (es) 2004-08-03 2007-04-10 Tissuemed Ltd Materiales adhesivos a tejido.
DE102004039728A1 (de) * 2004-08-16 2006-02-23 Beiersdorf Ag Wirkstoffhaltiges Tape zur Behandlung von Gelenkerkrankungen
US20060134188A1 (en) * 2004-12-20 2006-06-22 Hans-Peter Podhaisky Transdermal pharmaceutical preparation with a progesterone A-specific ligand (PRASL) as active ingredient
DE102004062182B4 (de) * 2004-12-20 2007-06-06 Bayer Schering Pharma Ag Transdermales Pflaster mit Progesteron A-Spezifische Liganden (PRASL) als Wirkstoff
KR100663163B1 (ko) 2005-10-24 2007-01-02 (주)아모레퍼시픽 비스테로이드성 소염진통제를 함유하는 경피 투여 제제
US8133336B2 (en) 2006-02-03 2012-03-13 Tissuemed Limited Tissue-adhesive materials
US8408781B2 (en) * 2006-02-21 2013-04-02 Charles D. Welker System, method and apparatus for entraining air in concrete
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
JP2012504163A (ja) * 2008-09-30 2012-02-16 テイコク ファーマ ユーエスエー インコーポレーテッド 経皮持続送達ドネペジル組成物および該組成物を使用する方法
CN101721394B (zh) * 2008-10-29 2013-04-17 大连理工大学 一种格拉司琼和/或其盐酸盐贴剂
CN101502499B (zh) * 2009-03-13 2011-07-27 北京化工大学 一种布洛芬经皮释放贴剂及其制备方法
MX337166B (es) 2009-06-24 2016-02-15 Composicion topica que contiene ibuoprofeno.
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
WO2010151241A1 (en) 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
JP6158082B2 (ja) 2010-07-17 2017-07-05 メルク パテント ゲーエムベーハー 浸透と作用の増強
CN105920603B (zh) 2010-12-29 2022-02-11 战略科学与技术有限责任公司 ***功能障碍和其它适应症的治疗
US9289495B2 (en) 2010-12-29 2016-03-22 Strategic Science & Technologies, Llc Systems and methods for treatment of allergies and other indications
CA2896336C (en) * 2012-12-28 2021-10-19 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of non-steroidal anti-inflammatory agents
EP2968652B1 (en) 2013-03-13 2020-07-22 Avery Dennison Corporation Improving adhesive properties
CN107072886A (zh) 2014-10-21 2017-08-18 宝洁公司 用于改善皮肤外观的试剂盒
WO2017070082A1 (en) 2015-10-22 2017-04-27 The Procter & Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
EP3365066B1 (en) 2015-10-22 2019-11-20 The Procter and Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
EP3364935B1 (en) 2015-10-22 2019-11-20 The Procter and Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
WO2018073227A1 (de) * 2016-10-18 2018-04-26 Lts Lohmann Therapie-Systeme Ag Zweischichtiges topisches therapeutisches system
CN110167642B (zh) 2017-01-09 2022-06-07 宝洁公司 具有可溶性膜的阻隔贴片和改善皮肤外观的方法
US10857076B2 (en) 2017-01-09 2020-12-08 The Procter & Gamble Company Barrier patch with soluble film and methods of improving skin appearance
US10751265B2 (en) 2017-01-09 2020-08-25 The Procter & Gamble Barrier patch with soluble film and methods of improving skin appearance
WO2018237214A1 (en) 2017-06-22 2018-12-27 The Procter & Gamble Company BEAUTY MASK FILMS COMPRISING A WATER SOLUBLE LAYER AND A VACUUM EVAPORATED COATING
WO2019183010A1 (en) 2018-03-19 2019-09-26 The Procter & Gamble Company Method of making a barrier patch with soluble film
KR101964264B1 (ko) * 2018-09-04 2019-04-01 한국생산기술연구원 점착소재 및 이의 이용
KR102600712B1 (ko) * 2021-09-27 2023-11-10 단국대학교 천안캠퍼스 산학협력단 체온감응형 고분자를 이용한 항류머티스제의 전달용 약제학적 조성물, 이를 포함하는 패치 및 이의 제조방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011471B1 (en) * 1978-11-17 1983-02-09 SMITH &amp; NEPHEW RESEARCH LIMITED Adhesive-coated sheet material incorporating anti-bacterial substances
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4938964A (en) 1987-12-09 1990-07-03 Showa Denko Kabushiki Kaisha External dermatological composition
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
FR2635979B1 (fr) * 1988-09-07 1992-05-29 Lhd Lab Hygiene Dietetique Dispositif auto-adhesif d'administration d'un principe actif par voie percutanee
WO1990006120A1 (en) * 1988-12-01 1990-06-14 Schering Corporation Compositions for transdermal delivery of estradiol
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
JP2875611B2 (ja) * 1990-08-29 1999-03-31 エーザイ株式会社 ケイ酸カルシウム含有外用剤
DE69228313T2 (de) * 1991-08-30 1999-09-23 Hisamitsu Pharmaceutical Co Entzündungshemmendes, analgetisches pflaster
IT1253265B (it) * 1991-11-25 1995-07-14 Rotta Research Lab Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo.
JPH05238931A (ja) 1992-02-27 1993-09-17 Nitto Denko Corp 貼付剤
GB2273044B (en) 1992-12-02 1997-04-09 Pacific Chem Co Ltd Medicinal patches for percutaneous administration
DE4339400A1 (de) * 1993-11-18 1995-05-24 Hexal Pharma Gmbh Wirkstoffpflaster
ZA945718B (en) * 1993-08-03 1995-03-09 Osi Specialties Inc Process for forming polyurethane foam using mechanical cooling and an additive
FR2719770A1 (fr) * 1994-05-11 1995-11-17 Lhd Lab Hygiene Dietetique Système matriciel pour administration transdermique d'ibuprofène et procédé de préparation.
DE69535737T2 (de) * 1994-09-16 2009-04-09 Hisamitsu Pharmaceutical Co., Inc., Tosu-shi Pflaster zur externen anwendung
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
KR100228514B1 (ko) * 1996-09-05 1999-11-01 한승수 비스테로이드성 소염진통제를 활성성분으로 하는 경피흡수제제의 제조방법
DE19706824C1 (de) * 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften

Also Published As

Publication number Publication date
HUP0103715A3 (en) 2002-11-28
CN1222280C (zh) 2005-10-12
RU2212232C2 (ru) 2003-09-20
CA2336732C (en) 2007-05-29
DE19830649C2 (de) 2003-04-10
ATE251900T1 (de) 2003-11-15
IL140744A (en) 2007-05-15
ES2212584T3 (es) 2004-07-16
US6676962B1 (en) 2004-01-13
IL140744A0 (en) 2002-02-10
TR200100022T2 (tr) 2001-05-21
NZ509216A (en) 2002-07-26
CA2336732A1 (en) 2000-01-20
PL345535A1 (en) 2001-12-17
KR100549847B1 (ko) 2006-02-06
EP1094796A1 (de) 2001-05-02
ZA200100172B (en) 2001-07-18
AU750861B2 (en) 2002-08-01
DE59907381D1 (de) 2003-11-20
EP1094796B1 (de) 2003-10-15
JP2002520270A (ja) 2002-07-09
AR019343A1 (es) 2002-02-13
CZ2001118A3 (en) 2001-06-13
BR9911981B1 (pt) 2010-06-01
HU227839B1 (en) 2012-05-02
KR20010072666A (ko) 2001-07-31
DE19830649A1 (de) 2000-01-13
CZ290992B6 (cs) 2002-11-13
CN1308527A (zh) 2001-08-15
AU4907599A (en) 2000-02-01
PL192009B1 (pl) 2006-08-31
WO2000002539A1 (de) 2000-01-20
HUP0103715A2 (hu) 2002-05-29
TW577760B (en) 2004-03-01
MXPA01000128A (es) 2002-06-04

Similar Documents

Publication Publication Date Title
BR9911981A (pt) Esparadrapo tópico com anti-reumático não esteroidal com grupo ácido
KR850007208A (ko) 약산성욕 염조성물
DE69434507D1 (de) Haftklebstoffzusammensetzung und Klebeband, das diese verwendet
CR5749A (es) Compuestos con cianoacrilato,curables por radiacion
ES2081823T3 (es) Agente para la aplicacion transdermica, que contiene gestoden.
ATE86123T1 (de) Haertbare harzueberzogene folie mit verminderter klebrigkeit.
ES2158842T3 (es) Grapa quirurgica polimera.
DK0464573T3 (da) Plaster med højt indhold af blødgørende indholdsstoffer
ES2135613T3 (es) Articulo dental que contiene una pasta curable por luz.
BR8203211A (pt) Composicao base de chiclete de bola nao adesiva composicao formadora de pelicula nao adesiva e processo para preparar a composicao
FI851258L (fi) Flytande bestrykningskomposition som kan haerdas vid omgivningens temperatur.
BR9405688A (pt) Aperfeiçoamentos em composições adesivas sensíveis à pressão, repolpáveis
JPS5434362A (en) Curable organopolysiloxane composition
DE69403656D1 (de) Stabile, orale und absorbierbare therapeutische zusammensetzungen von nadh und nadph
BR9306683A (pt) Adesivo proteináceo curado com aldeído
AR023427A1 (es) Adhesivos de fundido en caliente basados en poliesteres sulfonados que incluyen un indicador de humedad.
DE60042830D1 (de) Acrylische kopolymere, selbstklebender acrylkleber, klebeband oder film und acrylische klebstoffzusammensetzung
BR8008765A (pt) Processo para deformacao permanente dos cabelos
ES2055259T3 (es) Camara sencilla para usarse con un estuche de pelicula que tiene un indicador del estado de exposicion de dicha pelicula.
DE68911208D1 (de) Selbstklebende, härtbare Organopolysiloxanzusammensetzung.
ES2051266T3 (es) Adhesivo de uso general alcalino, acuoso, a base de polimetacrilato.
SE7800195L (sv) Festorgan for blojor
ATE280574T1 (de) Isosorbiddinitrat enthaltendes pflaster
DE68927603D1 (de) Härtbare Polymerzusammensetzung
ES2192245T3 (es) Emplastos que contienen principios activos.

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/06/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2594 DE 24-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.