BR9907962A - Composição farmacêntica, composto, e, processo para preparar o mesmo - Google Patents

Composição farmacêntica, composto, e, processo para preparar o mesmo

Info

Publication number
BR9907962A
BR9907962A BR9907962-3A BR9907962A BR9907962A BR 9907962 A BR9907962 A BR 9907962A BR 9907962 A BR9907962 A BR 9907962A BR 9907962 A BR9907962 A BR 9907962A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
preparing
same
formula
Prior art date
Application number
BR9907962-3A
Other languages
English (en)
Inventor
Andrew John Barker
Jason Grant Kettle
Alan Wellington Faull
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of BR9907962A publication Critical patent/BR9907962A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA, COMPOSTO, E, PROCESSO PARA PREPARAR O MESMO". Composição farmacêutica que compreende um composto de fórmula (I) ou um sal farmaceuticamente aceitável, éster ou amida do mesmo, que é um inibidor de proteína-1 quimioatraente de monócito, e em que A e B formam uma cadeia alquileno opcionalmente substituído de maneira a formar um anel com os átomos de carbono ao qual eles estão conectados; X é CH~ 2~ ou SO~ 2~, R¹ é um anel arila ou heteroarila opcionalmente substituído; R² é um grupo orgânico especificado tais como carboxi, e R³ é hidrogênio ou um grupo orgânico especificado; em combinação com um veículo farmaceuticamente aceitável. Alguns compostos de fórmula (I) são novos e são reivindicados como tal.
BR9907962-3A 1998-02-17 1999-02-02 Composição farmacêntica, composto, e, processo para preparar o mesmo BR9907962A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9803226.1A GB9803226D0 (en) 1998-02-17 1998-02-17 Chemical compounds
PCT/GB1999/000332 WO1999040913A1 (en) 1998-02-17 1999-02-02 Chemical compounds

Publications (1)

Publication Number Publication Date
BR9907962A true BR9907962A (pt) 2000-10-24

Family

ID=10827054

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907962-3A BR9907962A (pt) 1998-02-17 1999-02-02 Composição farmacêntica, composto, e, processo para preparar o mesmo

Country Status (14)

Country Link
US (1) US6291507B1 (pt)
EP (1) EP1054667B1 (pt)
JP (1) JP2002502873A (pt)
KR (1) KR20010040996A (pt)
CN (1) CN1291095A (pt)
AT (1) ATE237327T1 (pt)
AU (1) AU745772B2 (pt)
BR (1) BR9907962A (pt)
CA (1) CA2317456A1 (pt)
DE (1) DE69906940T2 (pt)
GB (1) GB9803226D0 (pt)
NO (1) NO20004090L (pt)
NZ (1) NZ505586A (pt)
WO (1) WO1999040913A1 (pt)

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GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000626D0 (en) * 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
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TW201018661A (en) 2003-03-14 2010-05-16 Ono Pharmaceutical Co Heterocyclic rinf having nitrogen atom derivatives and medicament containing the derivatives as active ingredient
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Also Published As

Publication number Publication date
JP2002502873A (ja) 2002-01-29
CA2317456A1 (en) 1999-08-19
EP1054667B1 (en) 2003-04-16
WO1999040913A1 (en) 1999-08-19
AU745772B2 (en) 2002-03-28
NO20004090L (no) 2000-10-16
KR20010040996A (ko) 2001-05-15
NZ505586A (en) 2002-11-26
CN1291095A (zh) 2001-04-11
DE69906940D1 (de) 2003-05-22
GB9803226D0 (en) 1998-04-08
AU2432799A (en) 1999-08-30
EP1054667A1 (en) 2000-11-29
ATE237327T1 (de) 2003-05-15
NO20004090D0 (no) 2000-08-16
DE69906940T2 (de) 2003-12-24
US6291507B1 (en) 2001-09-18

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTA A 5O, 6O, 7O E 8O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.