BR9907847A - Agentes anti-inflamatórios seletivos para glucocorticóides - Google Patents

Agentes anti-inflamatórios seletivos para glucocorticóides

Info

Publication number
BR9907847A
BR9907847A BR9907847-3A BR9907847A BR9907847A BR 9907847 A BR9907847 A BR 9907847A BR 9907847 A BR9907847 A BR 9907847A BR 9907847 A BR9907847 A BR 9907847A
Authority
BR
Brazil
Prior art keywords
glucocorticoids
inflammatory agents
selective anti
mammal
compounds
Prior art date
Application number
BR9907847-3A
Other languages
English (en)
Inventor
Michael J Coughlan
Michael E Kort
James P Edwards
Todd K Jones
Original Assignee
Abbott Lab
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, Ligand Pharm Inc filed Critical Abbott Lab
Publication of BR9907847A publication Critical patent/BR9907847A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

"AGENTES ANTI-INFLAMATóRIOS SELETIVOS PARA GLUCOCORTICóIDES" Compostos possuindo a Fórmula (I) são úteis para antagonizar, reprimir, agonizar ou modular parcial ou completamente o receptor glucocorticóide em um mamífero e tratamento de doenças imunes, autoimunes e inflamatórias em um mamífero. São também reveladas composições farmacêuticas compreendendo os compostos da Fórmula (I) e os processos para inibir doenças imunes e autoimunes em um mamífero.
BR9907847-3A 1998-02-13 1999-02-15 Agentes anti-inflamatórios seletivos para glucocorticóides BR9907847A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/023,913 US6380207B2 (en) 1998-02-13 1998-02-13 Glucocortiocoid-selective antiinflammatory agents
PCT/US1999/003210 WO1999041257A1 (en) 1998-02-13 1999-02-15 Glucocorticoid-selective antiinflammatory agents

Publications (1)

Publication Number Publication Date
BR9907847A true BR9907847A (pt) 2001-01-09

Family

ID=21817891

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907847-3A BR9907847A (pt) 1998-02-13 1999-02-15 Agentes anti-inflamatórios seletivos para glucocorticóides

Country Status (24)

Country Link
US (1) US6380207B2 (pt)
EP (1) EP1053240B1 (pt)
JP (1) JP2002503666A (pt)
KR (1) KR20010040940A (pt)
CN (1) CN1153771C (pt)
AT (1) ATE237620T1 (pt)
AU (1) AU760511B2 (pt)
BG (1) BG64213B1 (pt)
BR (1) BR9907847A (pt)
CA (1) CA2320911A1 (pt)
DE (1) DE69906938T2 (pt)
DK (1) DK1053240T3 (pt)
ES (1) ES2197618T3 (pt)
HK (1) HK1033309A1 (pt)
HU (1) HUP0100846A3 (pt)
IL (1) IL137509A0 (pt)
NO (1) NO20004052L (pt)
NZ (1) NZ506012A (pt)
PL (1) PL342999A1 (pt)
PT (1) PT1053240E (pt)
SK (1) SK284076B6 (pt)
TR (1) TR200002345T2 (pt)
WO (1) WO1999041257A1 (pt)
ZA (1) ZA99533B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
ES2246292T3 (es) 2000-10-30 2006-02-16 Pfizer Products Inc. Moduladores de receptor glucocorticoide.
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
US6831093B2 (en) 2002-01-22 2004-12-14 The Regents Of The University Of California Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
KR20050057086A (ko) 2002-08-28 2005-06-16 홀리스-에덴 파마슈티칼즈, 인코포레이티드 치료적 처치 방법
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
JP2006504736A (ja) * 2002-10-11 2006-02-09 リガンド・ファーマシューティカルズ・インコーポレイテッド 選択的プロゲステロンレセプター調節化合物としての５−（１’，１’−シクロアルキル／アルケニル）メチリデン１，２−ジヒドロ−５Ｈ−クロメノ［３，４−ｆ］キノリン
DE20301728U1 (de) * 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
HK1055058A2 (en) * 2002-10-11 2003-12-05 Ligand Pharm Inc 5-CYCLOALKENYL 5H-CHROMENO[3,4-f]QUINOLINE DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS
US7235662B2 (en) * 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
MXPA06001751A (es) * 2003-08-22 2006-05-12 Ligand Pharm Inc Derivados de 6-cicloamino-2-quinolinona como compuestos moduladores de receptor de androgeno.
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
EP1689390B1 (en) 2003-11-21 2011-02-09 Zalicus Inc. Methods and reagents for the treatment of inflammatory disorders
WO2005090282A1 (en) 2004-03-12 2005-09-29 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
AU2006259474B2 (en) 2005-06-17 2011-10-27 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
CA2620275A1 (en) 2005-08-26 2007-03-01 Thomas S. Scanlan Non-steroidal antiandrogens
JP2009514969A (ja) 2005-11-09 2009-04-09 コンビナトアールエックス インコーポレーティッド 医学的状態を治療するための方法、組成物、およびキット
CN101326155B (zh) * 2005-12-09 2012-06-20 霍夫曼-拉罗奇有限公司 作为抗炎剂的丙酰胺化合物
CA2632109A1 (en) * 2005-12-09 2007-06-14 F. Hoffmann-La Roche Ag Glucocorticoid receptor modulators as antiinflammatory agents
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US9908182B2 (en) 2012-01-30 2018-03-06 Black & Decker Inc. Remote programming of a power tool
US8919456B2 (en) 2012-06-08 2014-12-30 Black & Decker Inc. Fastener setting algorithm for drill driver
US10011006B2 (en) 2013-08-08 2018-07-03 Black & Decker Inc. Fastener setting algorithm for drill driver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ176197A3 (cs) 1994-12-22 1998-09-16 Ligand Pharmaceuticals Incorporated Modulátory steroidových receptorů a způsoby jejich přípravy a použití
US5688810A (en) 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US5693133A (en) 1995-05-10 1997-12-02 Akzo Nobel Nv Asbestos free roof coatings

Also Published As

Publication number Publication date
KR20010040940A (ko) 2001-05-15
HUP0100846A2 (hu) 2001-09-28
TR200002345T2 (tr) 2000-11-21
AU2600399A (en) 1999-08-30
IL137509A0 (en) 2001-07-24
SK11962000A3 (sk) 2001-03-12
US6380207B2 (en) 2002-04-30
NO20004052D0 (no) 2000-08-11
CN1153771C (zh) 2004-06-16
ZA99533B (en) 1999-07-26
BG64213B1 (bg) 2004-05-31
HUP0100846A3 (en) 2003-03-28
WO1999041257A1 (en) 1999-08-19
EP1053240B1 (en) 2003-04-16
BG104698A (en) 2001-05-31
US20010049377A1 (en) 2001-12-06
AU760511B2 (en) 2003-05-15
ES2197618T3 (es) 2004-01-01
DE69906938D1 (de) 2003-05-22
EP1053240A1 (en) 2000-11-22
NO20004052L (no) 2000-10-12
NZ506012A (en) 2003-03-28
HK1033309A1 (en) 2001-08-24
CN1297451A (zh) 2001-05-30
DK1053240T3 (da) 2003-08-11
CA2320911A1 (en) 1999-08-19
PL342999A1 (en) 2001-07-16
ATE237620T1 (de) 2003-05-15
JP2002503666A (ja) 2002-02-05
PT1053240E (pt) 2003-09-30
DE69906938T2 (de) 2004-02-26
SK284076B6 (sk) 2004-09-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1945 DE 15 - 04 - 2008.