BR9813021A - Processo para preparação microbiana de aminoácidos da famìlia do aspartato e/ou glutamato e agente empregável no processo - Google Patents

Processo para preparação microbiana de aminoácidos da famìlia do aspartato e/ou glutamato e agente empregável no processo

Info

Publication number
BR9813021A
BR9813021A BR9813021-8A BR9813021A BR9813021A BR 9813021 A BR9813021 A BR 9813021A BR 9813021 A BR9813021 A BR 9813021A BR 9813021 A BR9813021 A BR 9813021A
Authority
BR
Brazil
Prior art keywords
aspartate
amino acids
microbial preparation
glutamate family
agent used
Prior art date
Application number
BR9813021-8A
Other languages
English (en)
Other versions
BRPI9813021B1 (pt
Inventor
Bernd Eikmanns
Petra Peters-Wendisch
Hermann Sahm
Original Assignee
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26040582&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9813021(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19831609A external-priority patent/DE19831609B4/de
Application filed by Forschungszentrum Juelich Gmbh filed Critical Forschungszentrum Juelich Gmbh
Publication of BR9813021A publication Critical patent/BR9813021A/pt
Publication of BRPI9813021B1 publication Critical patent/BRPI9813021B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Patente de Invenção:<B>"PROCESSO PARA PREPARAçãO MICROBIANA DE AMINOáCIDOS DA FAMìLIA DO ASPARTATO E/OU GLUTAMATO E AGENTE EMPREGáVEL NO PROCESSO"<D>. A presente invenção refere-se a um processo para preparação microbiana de aminoácidos da família do aspartato e/ou glutamato, pelo qual a atividade piruvato-carboxilase é elevada por modificação genética da enzima e/ou a referida expressão genética piruvato-carboxilase de um microorganismo produtor de aminoácidos é elevada. Além disso a presente invenção refere-se a um gene piruvato-carboxilase assim como a outros agentes empregáveis no processo de acordo com a invenção.
BRPI9813021A 1997-10-04 1998-09-30 processo para a preparação microbiana de aminoácidos de l-lisina, l-treonina, l-homosserina e glutamato, vetor, e célula transformada BRPI9813021B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19743894 1997-10-04
DE19831609A DE19831609B4 (de) 1997-10-04 1998-07-14 Verfahren zur Herstellung von Aminosäuren der Aspartat- und/oder Glutamatfamilie und im Verfahren einsetzbare Mittel
PCT/EP1998/006210 WO1999018228A2 (de) 1997-10-04 1998-09-30 Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel

Publications (2)

Publication Number Publication Date
BR9813021A true BR9813021A (pt) 2000-08-15
BRPI9813021B1 BRPI9813021B1 (pt) 2016-04-05

Family

ID=26040582

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9813021A BRPI9813021B1 (pt) 1997-10-04 1998-09-30 processo para a preparação microbiana de aminoácidos de l-lisina, l-treonina, l-homosserina e glutamato, vetor, e célula transformada

Country Status (15)

Country Link
US (2) US7267967B1 (pt)
EP (1) EP1015621B1 (pt)
JP (1) JP2002508921A (pt)
CN (1) CN1323171C (pt)
AT (1) ATE290602T1 (pt)
AU (1) AU741038B2 (pt)
BR (1) BRPI9813021B1 (pt)
CA (1) CA2305577A1 (pt)
DE (1) DE59812638D1 (pt)
ES (1) ES2238773T3 (pt)
HU (1) HU224055B1 (pt)
ID (1) ID26644A (pt)
RU (1) RU2231552C2 (pt)
SK (1) SK284235B6 (pt)
WO (1) WO1999018228A2 (pt)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999053035A1 (en) * 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
DE19931317A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin
US6171833B1 (en) 1998-12-23 2001-01-09 Massachusetts Institute Of Technology Pyruvate carboxylase from corynebacterium glutamicum
CA2356446A1 (en) * 1998-12-23 2000-07-06 Massachusetts Institute Of Technology Pyruvate carboxylase from corynebacterium glutamicum
JP2000201692A (ja) 1999-01-13 2000-07-25 Ajinomoto Co Inc 発酵法によるｌ―グルタミン酸の製造法
TW200734459A (en) 1999-10-04 2007-09-16 Ajinomoto Kk Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic coryneform bacteria
DE19947792A1 (de) * 1999-10-05 2001-04-12 Degussa Neue für das Irp Gen codierende Nukleotidsequenzen
US7132272B2 (en) 1999-10-05 2006-11-07 Degussa Ag Nucleotide sequence encoding corynebacterium glutamicum leucine response regulatory protein
RU2207376C2 (ru) * 1999-10-14 2003-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Способ получения l-аминокислоты методом ферментации, штамм бактерии escherichia coli - продуцент l-аминокислоты (варианты)
DE10021831A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das fadD15-Gen kodierende Nukleotidsequenzen
US6949374B2 (en) 2000-05-04 2005-09-27 Degussa Ag FadD15 gene of Corynebacterium glutamicum, encoding an acyl-CoA synthase polypeptide
DE10032350A1 (de) 2000-07-04 2002-01-24 Degussa Neue für das mdhA-Gen kodierende Nukleotidsequenzen
DE10039049A1 (de) 2000-08-10 2002-02-21 Degussa Neue für das IysR3-Gen kodierende Nukleotidsequenzen
AU2001276385A1 (en) * 2000-08-10 2002-02-18 Degussa A.G. Nucleotide sequences which code for the lysr3 gene
DE10042051A1 (de) * 2000-08-26 2002-03-07 Degussa Neue für das cstA-Gen kodierende Nukleotidsequenzen
DE10108223A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
MXPA03007456A (es) * 2001-02-21 2004-07-30 Basf Antiengesellschaft Metodo para producir acido d-pantotenico y/o las sales de este como aditivo en alimento para animales.
BRPI0207477B1 (pt) * 2001-02-21 2015-05-26 Basf Ag Processo para prepapar ácido d- pantotênico e/ou sais do mesmo
DE10108225A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
WO2003008607A2 (en) 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
WO2003008600A2 (en) 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
DK1414986T3 (da) * 2001-08-06 2009-01-19 Evonik Degussa Gmbh Coryforme bakterier, der frembringer kemiske forbindelser II
US8278076B2 (en) 2002-02-20 2012-10-02 University Of Georgia Research Foundation, Inc. Microbial production of pyruvate and pyruvate derivatives
DE10303571A1 (de) 2003-01-30 2004-08-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE10316109A1 (de) 2003-04-09 2004-10-21 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102004005836A1 (de) 2004-02-06 2005-09-15 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102004037572A1 (de) * 2004-08-03 2006-02-23 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
DE102005043979A1 (de) 2005-09-15 2007-03-22 Forschungszentrum Jülich GmbH Verfahren zur Produktion von Aminosäuren in aminosäureproduzierenden Mikroorganismen
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP3170889A1 (en) * 2006-09-15 2017-05-24 CJ Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
KR100830826B1 (ko) 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸または核酸の製造方法
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP1975241A1 (de) 2007-03-29 2008-10-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
JP2010226956A (ja) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Ｌ−リジンの製造法
BRPI0816429A2 (pt) 2007-09-04 2019-09-24 Ajinomoto Kk microorganismo, e, método para a produção de um l-aminoácido.
DE102007044134A1 (de) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102007052270A1 (de) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2060636A1 (de) 2007-11-14 2009-05-20 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
WO2009093703A1 (ja) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Ｌ-アミノ酸の製造法
EP2098597A1 (de) 2008-03-04 2009-09-09 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
US8932861B2 (en) 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
DE102008002309A1 (de) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
CN102177246B (zh) 2008-09-08 2015-02-11 味之素株式会社 生产l-氨基酸的微生物和l-氨基酸的生产方法
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2267145A1 (de) 2009-06-24 2010-12-29 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
WO2011013707A1 (ja) 2009-07-29 2011-02-03 味の素株式会社 Ｌ-アミノ酸の製造法
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2013013329A (ja) 2009-11-06 2013-01-24 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
AU2010346674B2 (en) * 2010-02-25 2013-08-22 Colgate-Palmolive Company Utilization of Agro Residual Substrates for Fermentative Production of L-Arginine
KR101145943B1 (ko) 2010-03-11 2012-05-15 씨제이제일제당 (주) Ｌ-아미노산 생산능을 갖는 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
JP5796282B2 (ja) * 2010-08-31 2015-10-21 東レ株式会社 コリネ型細菌による化学品の製造方法
RU2496867C2 (ru) * 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
RU2615454C1 (ru) * 2011-12-21 2017-04-04 СиДжей ЧеилДжеданг Корпорейшн Способ получения L-лизина с использованием микроорганизмов, обладающих способностью продуцировать L-лизин
JP5831669B2 (ja) 2013-05-13 2015-12-09 味の素株式会社 Ｌ−アミノ酸の製造法
KR20160007505A (ko) * 2013-05-17 2016-01-20 질레코 인코포레이티드 바이오매스의 가공처리
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
EP3053999B1 (en) 2013-10-02 2019-11-20 Ajinomoto Co., Inc. Ammonia control apparatus and ammonia control method
ES2694011T3 (es) 2013-10-21 2018-12-17 Ajinomoto Co., Inc. Método para producir L-aminoácido
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
CN105505969A (zh) * 2014-09-26 2016-04-20 中国科学院天津工业生物技术研究所 一种提高l-苏氨酸转化率的方法及其应用
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
DE102017004751A1 (de) 2017-05-18 2018-11-22 Forschungszentrum Jülich GmbH Pyruvatcarboxylase und für die Pyruvatcarboxylase kodierende DNA, Plasmid enthaltend die DNA, sowie Mikroorganismus zur Produktion und verfahren zur Herstellung von Produkten, deren Bioynthese Oxalacetat als Vorstufe beeinhaltet und Chromosom
EP3467099A1 (en) 2017-10-05 2019-04-10 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
CN112969797A (zh) 2018-09-07 2021-06-15 阿彻丹尼尔斯米德兰德公司 工程化棒状杆菌属菌株
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN113755492B (zh) * 2020-07-20 2023-05-30 中国科学院天津工业生物技术研究所 丙酮酸羧化酶基因启动子的突变体及其应用
CN116583605A (zh) 2020-10-28 2023-08-11 味之素株式会社 L-氨基酸的制造方法
WO2023222505A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of monomers of bisucaberins, desferrioxamines and analogs thereof
WO2023222510A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of desferrioxamines and analogs thereof
WO2023222515A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of bisucaberins, desferrioxamines and analogs thereof
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223754B (en) 1988-09-12 1992-07-22 Degussa Dna encoding phosphoenolpyruvate carboxylase
DE4201085A1 (de) 1992-01-17 1993-07-22 Degussa Verfahren zur erhoehung der leistungsfaehigkeit l-lysin ausscheidender coryneformer bakterien
CA2169170C (en) * 1993-08-24 2007-01-09 Masakazu Sugimoto Mutant phosphoenolpyruvate carboxylase, its gene, and production method of amino acid
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
JP2003504065A (ja) * 1999-07-09 2003-02-04 デグサ アクチエンゲゼルシャフト Ｏｐｃａ遺伝子をコードするヌクレオチド配列
DE19941478A1 (de) * 1999-09-01 2001-03-08 Degussa Neue für das thrE-Gen codierende Nukleotidsequenzen und Verfahren zur fermentativen Herstellung von L-Threonin mit coryneformen Bakterien
DE19959329A1 (de) * 1999-12-09 2001-06-13 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE10154102A1 (de) * 2001-11-02 2003-05-15 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae

Also Published As

Publication number Publication date
SK4812000A3 (en) 2000-09-12
CA2305577A1 (en) 1999-04-15
EP1015621A2 (de) 2000-07-05
AU741038B2 (en) 2001-11-22
HU224055B1 (hu) 2005-05-30
US7267967B1 (en) 2007-09-11
EP1015621B1 (de) 2005-03-09
DE59812638D1 (de) 2005-04-14
CN1323171C (zh) 2007-06-27
ATE290602T1 (de) 2005-03-15
JP2002508921A (ja) 2002-03-26
WO1999018228A3 (de) 1999-05-20
HUP0004381A3 (en) 2003-08-28
RU2231552C2 (ru) 2004-06-27
US20070202571A1 (en) 2007-08-30
ID26644A (id) 2001-01-25
WO1999018228A2 (de) 1999-04-15
ES2238773T3 (es) 2005-09-01
HUP0004381A1 (en) 2001-03-28
CN1275167A (zh) 2000-11-29
AU1148299A (en) 1999-04-27
BRPI9813021B1 (pt) 2016-04-05
SK284235B6 (en) 2004-11-03

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