BR9810387A - (s) 3, 4, 5-trimethoxybenzoate of 2-methylamino-2-phenyl-n-butyl, and its application for the treatment of chronic pain - Google Patents

(s) 3, 4, 5-trimethoxybenzoate of 2-methylamino-2-phenyl-n-butyl, and its application for the treatment of chronic pain

Info

Publication number
BR9810387A
BR9810387A BR9810387-3A BR9810387A BR9810387A BR 9810387 A BR9810387 A BR 9810387A BR 9810387 A BR9810387 A BR 9810387A BR 9810387 A BR9810387 A BR 9810387A
Authority
BR
Brazil
Prior art keywords
phenyl
butyl
treatment
chronic pain
trimethoxybenzoate
Prior art date
Application number
BR9810387-3A
Other languages
Portuguese (pt)
Inventor
Henri Jacobelli
Agnes Grouhel
Original Assignee
Parke Davis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis filed Critical Parke Davis
Publication of BR9810387A publication Critical patent/BR9810387A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção; <B>"(S)3,4,5-TRIMETOXIBENZOATO DE 2-METILAMINO-2-FENIL-N-BUTILA, E SUA APLICAçãO PARA O TRATAMENTO DE DOR CRÈNICA"<D>. A presente invenção providencia (S) 3,4,5-trimetoxibenzoato de 2-metilamino-2-fenil-n-butila (S) para uso no tratamento da dor crónica, tendo a Fórmula (I). A presente invenção também provê métodos de uso do composto de Fórmula (I), e a composições farmacêuticas que contêm o composto de Fórmula (I).Invention Patent; <B> "(S) 3,4,5-TRIMETOXYBENZOATE OF 2-METHYLAMINE-2-PHENYL-N-BUTYL, AND ITS APPLICATION FOR THE TREATMENT OF CHRONIC PAIN" <D>. The present invention provides 2-methylamino-2-phenyl-n-butyl (S) 3,4,5-trimethoxybenzoate (S) for use in the treatment of chronic pain, having Formula (I). The present invention also provides methods of using the compound of Formula (I), and pharmaceutical compositions containing the compound of Formula (I).

BR9810387-3A 1997-06-30 1998-06-23 (s) 3, 4, 5-trimethoxybenzoate of 2-methylamino-2-phenyl-n-butyl, and its application for the treatment of chronic pain BR9810387A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9708323A FR2765218B1 (en) 1997-06-30 1997-06-30 2 (METHYLAMINO-2-PHENYL-N- BUTYL) 3,4,5-TRIMETHOXYBENZOATE (S), ITS APPLICATION TO THE TREATMENT OF CHRONIC PAIN
PCT/EP1998/003825 WO1999001417A1 (en) 1997-06-30 1998-06-23 (S) 2-METHYLAMINO-2-PHENYL-n-BUTYL 3,4,5-TRIMETHOXYBENZOATE, ITS APPLICATION TO THE TREATMENT OF CHRONIC PAIN

Publications (1)

Publication Number Publication Date
BR9810387A true BR9810387A (en) 2000-09-05

Family

ID=9508729

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810387-3A BR9810387A (en) 1997-06-30 1998-06-23 (s) 3, 4, 5-trimethoxybenzoate of 2-methylamino-2-phenyl-n-butyl, and its application for the treatment of chronic pain

Country Status (16)

Country Link
EP (1) EP0993436A1 (en)
JP (1) JP2002508776A (en)
KR (1) KR20010014294A (en)
AU (1) AU731887B2 (en)
BR (1) BR9810387A (en)
CA (1) CA2285479A1 (en)
FR (1) FR2765218B1 (en)
HU (1) HUP0003023A3 (en)
IL (1) IL133398A0 (en)
IS (1) IS5324A (en)
MX (1) MXPA99009120A (en)
NO (1) NO996496D0 (en)
NZ (1) NZ500212A (en)
PL (1) PL337665A1 (en)
WO (1) WO1999001417A1 (en)
ZA (1) ZA985668B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110549A1 (en) 1999-12-23 2001-06-27 Warner-Lambert Company Use of trimebutine for treating pain
FR2927076B1 (en) 2008-01-31 2010-03-26 Oroxcell 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2948660B1 (en) 2009-07-30 2011-08-19 Oroxcell 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2013134869A1 (en) * 2012-03-12 2013-09-19 Gicare Pharma Inc. Novel sulfonate-based trimebutine salts
RU2752086C1 (en) * 2020-04-27 2021-07-22 Общество С Ограниченной Ответственностью "Валента-Интеллект" New [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimetoxybenzoate 4-methyl-2h-chromen-2-on-7-ilsulphate compound and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols

Also Published As

Publication number Publication date
IS5324A (en) 1999-12-28
ZA985668B (en) 1999-01-25
HUP0003023A3 (en) 2001-12-28
AU8540598A (en) 1999-01-25
NO996496L (en) 1999-12-27
HUP0003023A2 (en) 2001-01-29
IL133398A0 (en) 2001-04-30
WO1999001417A1 (en) 1999-01-14
MXPA99009120A (en) 2005-01-10
FR2765218A1 (en) 1998-12-31
NZ500212A (en) 2001-07-27
AU731887B2 (en) 2001-04-05
CA2285479A1 (en) 1999-01-14
NO996496D0 (en) 1999-12-27
EP0993436A1 (en) 2000-04-19
FR2765218B1 (en) 1999-08-13
PL337665A1 (en) 2000-08-28
KR20010014294A (en) 2001-02-26
JP2002508776A (en) 2002-03-19

Similar Documents

Publication Publication Date Title
BR9814375A (en) Inhibition of raf kinase using symmetrical and asymmetric substituted diphenyl urea
BR9910180A (en) Pharmaceutical composition, processes for the treatment of a condition associated with reduced nicotine transmission, for the identification of a positive modulator of a nicotinic receptor agonist and for the identification of a compound, compound, and use of a positive modulator of a nicotinic receptor agonist
ITRM940621A0 (en) &#34;STABILIZED PHARMACEUTICAL COMPOSITION, RELATED SOLVENT AND PREPARATION PROCEDURE&#34;
BR9507656A (en) Compound use of a compound Pharmaceutical composition and processes for the treatment of a patient suffering from pain and for the preparation of a compound
IT1309427B1 (en) DIETARY OR PHARMACEUTICAL COMPOSITION USEFUL FOR THE PREVENTION OR TREATMENT OF HYPEROXIDE AND ITS USE
BR9709915A (en) Compound pharmaceutical composition use of the compound and processes for the treatment or prevention of physiological disorders associated with an excess of tachykinins and for the preparation of the compound
TR199801180T2 (en) New compounds with analgesic effect.
FI973828A0 (en) Compounds and compositions for administering the active ingredients
ES2157993T3 (en) BENZOILGUANIDINAS, ITS PREPARATION AND ITS USE IN MEDICINES.
BR9909138A (en) Combination for the treatment of alcohol and drug addiction containing an opioid antagonist and a nmda receptor complex modulator
IT1289581B1 (en) MIXTURE, COMPOSITION FOR THE PROTECTION OF PLANTS CONTAINING THE MIXTURE AND ITS USE
DE69512929T2 (en) AMINO ALCOHOL SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BR9610733A (en) Compound processes for the preparation of it and for the treatment of a mammal pharmaceutical composition and use of a compound
DE69311541T2 (en) COSMETIC OR PHARMACEUTICAL COMPOSITIONS FOR TOPICAL USE CONTAINING THE DEACYLATED GLYCEROPHOSPHOLIPIDES
RS49599B (en) Use of h+, k+ -atpaze inhibitors and glucocortifoids and pharmaceutical formulation
BR9813996A (en) 2-arylbenzo [b] thiophenes useful for the treatment of estrogen deprivation syndrome
SE9402880D0 (en) New peptide derivatives
EE03783B1 (en) A pharmaceutical composition for the treatment of epitheliomas and the use of an antibody or antibody molecule
BR9506748A (en) Pharmaceutical preparation compounds use of a compound and processes for the treatment of an individual suffering from pain and for the preparation of a compound
ES2135722T3 (en) 1,5-BENZODIACEPINES 5-HETEROCICLICAS MODULADORAS DE LA CCK OR DEL GASTRINA.
BR9810387A (en) (s) 3, 4, 5-trimethoxybenzoate of 2-methylamino-2-phenyl-n-butyl, and its application for the treatment of chronic pain
DE59914183D1 (en) DISPOSABLE DEVICE FOR A COMPOSITION OF A PHARMACEUTICALLY ACTIVE SUBSTANCE
BR9806083A (en) Pharmaceutical composition for the treatment of hapattite c
PT1017388E (en) Pharmaceutical composition containing IBUPROFEN AND DOMPERIDONE FOR THE TREATMENT OF ENXAQUECA
ATE220393T1 (en) BI-AROMATIC COMPOUNDS CONTAINING A HETEROETHYNYLENE BRIDGE AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.