BR9810280A - Proliposome powders for inhalation established by tocopherol. - Google Patents

Proliposome powders for inhalation established by tocopherol.

Info

Publication number
BR9810280A
BR9810280A BR9810280-0A BR9810280A BR9810280A BR 9810280 A BR9810280 A BR 9810280A BR 9810280 A BR9810280 A BR 9810280A BR 9810280 A BR9810280 A BR 9810280A
Authority
BR
Brazil
Prior art keywords
tocopherol
inhalation
established
powder
proliposome
Prior art date
Application number
BR9810280-0A
Other languages
Portuguese (pt)
Inventor
Katarina Bystroem
Per-Gunnar Nilsson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9810280A publication Critical patent/BR9810280A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<B>''PóS DE PROLIPOSSOMO PARA INALAçãO ESTABILIZADA POR TOCOFEROL''<D>. Um pó de poliprossomo é descrito, dito pó contendo numa fase única, partículas discretas que compreendem (1) um componente biologicamente ativo, (2) uma proporção estabilizada de tocoferol, e (3) um lipídio ou mistura de lipídios tendo uma temperatura de transição de fase, abaixo de 37 C. Um processo para preparação do pó e o uso farmacêutico do mesmo, também é descrito.<B> '' PROLIPOSOME POWERS FOR TOCOPHEROL STABILIZED INHALATION '' <D>. A polyprosome powder is described, said powder containing in a single phase, discrete particles comprising (1) a biologically active component, (2) a stabilized proportion of tocopherol, and (3) a lipid or mixture of lipids having a transition temperature phase, below 37 C. A process for preparing the powder and the pharmaceutical use of it, is also described.

BR9810280-0A 1997-06-27 1998-06-08 Proliposome powders for inhalation established by tocopherol. BR9810280A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88441997A 1997-06-27 1997-06-27
PCT/SE1998/001090 WO1999000111A1 (en) 1997-06-27 1998-06-08 Proliposome powders for inhalation stabilised by tocopherol

Publications (1)

Publication Number Publication Date
BR9810280A true BR9810280A (en) 2000-09-12

Family

ID=25384589

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810280-0A BR9810280A (en) 1997-06-27 1998-06-08 Proliposome powders for inhalation established by tocopherol.

Country Status (18)

Country Link
EP (1) EP1001749A1 (en)
JP (1) JP2002510311A (en)
KR (1) KR20010014163A (en)
CN (1) CN1260713A (en)
AU (1) AU729100B2 (en)
BR (1) BR9810280A (en)
CA (1) CA2295028A1 (en)
EE (1) EE9900601A (en)
HU (1) HUP0003207A3 (en)
ID (1) ID23192A (en)
IL (1) IL133478A0 (en)
IS (1) IS5304A (en)
NO (1) NO996439L (en)
NZ (1) NZ501672A (en)
PL (1) PL337723A1 (en)
SK (1) SK184899A3 (en)
TR (1) TR199903271T2 (en)
WO (1) WO1999000111A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
EP1138310A1 (en) * 2000-03-28 2001-10-04 Primacare S.A. Proliposomes
EP1138313A1 (en) * 2000-03-28 2001-10-04 Primacare S.A. Proliposomes
EP1138311A1 (en) * 2000-03-28 2001-10-04 Primacare S.A. Proliposomes
KR20080016621A (en) * 2005-06-09 2008-02-21 바이올리폭스 에이비 Method and composition for treating inflammatory disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
ES2676022T3 (en) * 2013-05-06 2018-07-16 Dsm Ip Assets B.V. Formulation of vitamin E powder
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
CN105078963B (en) * 2015-09-29 2018-06-22 中山大学 Alpha-tocopherol is preparing the application in treating snail fever drug
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR002009A1 (en) * 1994-12-22 1998-01-07 Astra Ab PHARMACEUTICAL COMPOSITION, PROCEDURE FOR THE MANUFACTURE OF A PROLIPOSOMA POWDER AS USED IN SUCH COMPOSITION, PROCEDURE FOR LAMANUFACTURE OF SUCH COMPOSITION, USE OF SUCH PHARMACEUTICAL COMPOSITION IN THE MANUFACTURE OF A DISPOSAL MEDICINAL PRODUCT.

Also Published As

Publication number Publication date
KR20010014163A (en) 2001-02-26
SK184899A3 (en) 2000-05-16
AU729100B2 (en) 2001-01-25
ID23192A (en) 2000-03-23
EP1001749A1 (en) 2000-05-24
WO1999000111A1 (en) 1999-01-07
CN1260713A (en) 2000-07-19
AU7945698A (en) 1999-01-19
NO996439L (en) 2000-02-28
NO996439D0 (en) 1999-12-23
CA2295028A1 (en) 1999-01-07
EE9900601A (en) 2000-08-15
HUP0003207A3 (en) 2001-03-28
HUP0003207A2 (en) 2001-02-28
IS5304A (en) 1999-12-15
JP2002510311A (en) 2002-04-02
IL133478A0 (en) 2001-04-30
TR199903271T2 (en) 2000-08-21
PL337723A1 (en) 2000-08-28
NZ501672A (en) 2001-06-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A,8A E 9AANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.