BR9809439A - Processos para preparação de benzotiofenos - Google Patents

Processos para preparação de benzotiofenos

Info

Publication number
BR9809439A
BR9809439A BR9809439-4A BR9809439A BR9809439A BR 9809439 A BR9809439 A BR 9809439A BR 9809439 A BR9809439 A BR 9809439A BR 9809439 A BR9809439 A BR 9809439A
Authority
BR
Brazil
Prior art keywords
processes
preparation
benzothiophenes
benzotiophenes
intermediates
Prior art date
Application number
BR9809439-4A
Other languages
English (en)
Inventor
John Mcneil Mcgill Iii
Tony Yantao Zhang
Jerry Wayne Misner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9809439A publication Critical patent/BR9809439A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção:<B>"PROCESSOS PARA PREPARAçãO DE BENZOTIOFENOS"<D>. A presente invenção refere-se a intermediários e a processos para preparação de benzotiofenos.
BR9809439-4A 1997-04-30 1998-04-28 Processos para preparação de benzotiofenos BR9809439A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4517797P 1997-04-30 1997-04-30
PCT/US1998/008509 WO1998049156A1 (en) 1997-04-30 1998-04-28 Processes for preparing benzothiophenes

Publications (1)

Publication Number Publication Date
BR9809439A true BR9809439A (pt) 2000-06-13

Family

ID=21936426

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809439-4A BR9809439A (pt) 1997-04-30 1998-04-28 Processos para preparação de benzotiofenos

Country Status (11)

Country Link
US (1) US6090949A (pt)
EP (1) EP0875510A1 (pt)
JP (1) JP2001522372A (pt)
KR (1) KR20010020378A (pt)
CN (1) CN1253556A (pt)
AU (1) AU7261398A (pt)
BR (1) BR9809439A (pt)
CA (1) CA2287943A1 (pt)
HU (1) HUP0003187A3 (pt)
IL (1) IL132569A0 (pt)
WO (1) WO1998049156A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1832583A1 (en) 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Novel raloxifene sulphuric acid addition salts and/or solvates thereof, and pharmaceutical compositions comprising these
DE602005009208D1 (de) 2004-07-30 2008-10-02 Salvat Lab Sa Tyrosinderivate als ppar-gamma-modulatoren
WO2008047105A1 (en) 2006-10-17 2008-04-24 Cipla Limited Crystalline form of benzothiophene compound and process for preparation thereof
CN104031022A (zh) * 2014-03-20 2014-09-10 浙江省医学科学院 盐酸雷洛昔芬的关键中间体及其中间产物的制备方法
CN105064445B (zh) * 2015-07-27 2017-10-31 徐工集团工程机械股份有限公司科技分公司 一种装载机用多功能手柄操纵控制***

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138163A (en) * 1965-05-21 1968-12-27 Bristol Myers Co Benzothiophene derivatives having anti-fertility properties
US3394125A (en) * 1965-10-23 1968-07-23 Bristol Myers Co 2-phenyl-3-tertiary-aminoalkoxy phenyl-and corresponding tertiaryaminoalkyl thio benzfurans substituted in the benzo nucleus with an alkoxy or tertiaryamino alkoxy or alkylthio group
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4358593A (en) * 1981-04-03 1982-11-09 Eli Lilly And Company Process for preparing 3-(4-aminoethoxybenzoyl)benzo[b]thiophenes
GB2097788B (en) * 1981-04-03 1985-04-24 Lilly Co Eli Benzothiophene compounds and process for preparing them
IL65379A0 (en) * 1981-04-03 1982-05-31 Lilly Co Eli Process for preparing acylated benzothiophenes
IL65378A (en) * 1981-04-03 1986-02-28 Lilly Co Eli Process for preparing 3-(4-aminoethoxybenzoyl)benzo-(b)thiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US5175184A (en) * 1982-10-19 1992-12-29 Kotobuki Seiyaku Company Limited Benzothiophene derivatives and antihyperuricemia thereof
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
DE4117512A1 (de) * 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
TW383306B (en) * 1992-12-22 2000-03-01 Lilly Co Eli New use of 2-phenyl-3-aroylbenzothiophenes in lowering serum cholesterol
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5523416A (en) * 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
US5552412A (en) * 1995-01-09 1996-09-03 Pfizer Inc 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis

Also Published As

Publication number Publication date
JP2001522372A (ja) 2001-11-13
KR20010020378A (ko) 2001-03-15
HUP0003187A2 (hu) 2001-05-28
AU7261398A (en) 1998-11-24
US6090949A (en) 2000-07-18
IL132569A0 (en) 2001-03-19
WO1998049156A1 (en) 1998-11-05
CA2287943A1 (en) 1998-11-05
EP0875510A1 (en) 1998-11-04
HUP0003187A3 (en) 2002-04-29
CN1253556A (zh) 2000-05-17

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Legal Events

Date Code Title Description
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1891 DE 03/04/2007.