BR9803346A - Microorganismos e processo para a preparação fermentativa del-cisteìna, l-cistina, n-acetil-serina ou derivados de tiazoldina. - Google Patents

Microorganismos e processo para a preparação fermentativa del-cisteìna, l-cistina, n-acetil-serina ou derivados de tiazoldina.

Info

Publication number
BR9803346A
BR9803346A BR9803346-8A BR9803346A BR9803346A BR 9803346 A BR9803346 A BR 9803346A BR 9803346 A BR9803346 A BR 9803346A BR 9803346 A BR9803346 A BR 9803346A
Authority
BR
Brazil
Prior art keywords
cystine
cysteine
microorganisms
fermentative preparation
derivatives
Prior art date
Application number
BR9803346-8A
Other languages
English (en)
Other versions
BR9803346B1 (pt
Inventor
Christoph Winterhalter
Walfred Leinfelder
Original Assignee
Consortium Elektrochem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consortium Elektrochem Ind filed Critical Consortium Elektrochem Ind
Publication of BR9803346A publication Critical patent/BR9803346A/pt
Publication of BR9803346B1 publication Critical patent/BR9803346B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Patente de Invenção: <B>''MICROORGANISMOS E PROCESSO PARA A PREPARAçãO FERMENTATIVA DE L-CISTEìNA, L-CISTINA, N-ACETIL-SERINA OU DERIVADOS DE TIAZOLIDINA''<D>. A invenção refere-se a microorganismos e a processos para a preparação fermentativa de L-cisteina, L-cistina, N-acetil-serina ou derivados de tiazolidina. A cepa de microorganismos de acordo com a invenção, que é adequada para a preparação fermentativa de L-cisteína, L-cistina, N-acetilserina e/ou derivados de tiazolidina, caracterizada pelo fato de que ela sobreexpressa pelo menos um gen que codifica uma proteína, a qual é adequada para a extração direta, a partir da célula, de antibióticos ou outras substâncias tóxicos para microorganismo.
BRPI9803346-8B1A 1997-06-19 1998-06-17 Cepa de microorganismos transformados, bem como processo para a preparação fermentativa de l-cisteína, l-cistina, n-acetil-serina ou derivados de tiazolidina BR9803346B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19726083A DE19726083A1 (de) 1997-06-19 1997-06-19 Mikroorganismen und Verfahren zur fermentativen Herstellung von L-Cystein, L-Cystin, N-Acetyl-Serin oder Thiazolidinderivaten

Publications (2)

Publication Number Publication Date
BR9803346A true BR9803346A (pt) 2000-02-08
BR9803346B1 BR9803346B1 (pt) 2013-11-12

Family

ID=7833043

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9803346-8B1A BR9803346B1 (pt) 1997-06-19 1998-06-17 Cepa de microorganismos transformados, bem como processo para a preparação fermentativa de l-cisteína, l-cistina, n-acetil-serina ou derivados de tiazolidina

Country Status (14)

Country Link
US (1) US5972663A (pt)
EP (1) EP0885962B1 (pt)
JP (1) JP2992010B2 (pt)
KR (1) KR19990007062A (pt)
CN (1) CN100347291C (pt)
AT (1) ATE293165T1 (pt)
BR (1) BR9803346B1 (pt)
CA (1) CA2235419C (pt)
DE (2) DE19726083A1 (pt)
DK (1) DK0885962T3 (pt)
ES (1) ES2236845T3 (pt)
HU (1) HU224343B1 (pt)
ID (1) ID20467A (pt)
PL (1) PL195784B1 (pt)

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JP2992010B2 (ja) 1999-12-20
US5972663A (en) 1999-10-26
CN1203274A (zh) 1998-12-30
HUP9801369A3 (en) 2000-08-28
HU224343B1 (hu) 2005-08-29
DK0885962T3 (da) 2005-05-09
HU9801369D0 (en) 1998-08-28
BR9803346B1 (pt) 2013-11-12
KR19990007062A (ko) 1999-01-25
ATE293165T1 (de) 2005-04-15
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