BR9708413A - Proteìnas de superfìcie de alto peso molecular de haemophilus não tipificável - Google Patents

Proteìnas de superfìcie de alto peso molecular de haemophilus não tipificável

Info

Publication number
BR9708413A
BR9708413A BR9708413-1A BR9708413A BR9708413A BR 9708413 A BR9708413 A BR 9708413A BR 9708413 A BR9708413 A BR 9708413A BR 9708413 A BR9708413 A BR 9708413A
Authority
BR
Brazil
Prior art keywords
molecular weight
high molecular
surface proteins
haemophilus
weight surface
Prior art date
Application number
BR9708413-1A
Other languages
English (en)
Inventor
Stephen J Barenkamp
Original Assignee
St Louis University And Washin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Louis University And Washin filed Critical St Louis University And Washin
Publication of BR9708413A publication Critical patent/BR9708413A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROTEìNAS DE SUPERFìCIE DE ALTO PESO MOLECULAR DE HAEMOPHILUS NãO TIPIFICáVEL Proteínas de superfície de alto peso molecular de <MU>Haemophilus influezae<MV> que exibem propriedades imunogênicas e genes codificando as mesmas são aqui descritas. Especificamente, genes codificando para duas proteínas de alto peso molecular imunodominantes, HMW1 e HMW2 foram clonados, expressos e sequenciados. Enquanto genes codificando para proteínas de alto peso molecular HMW3 e HMW4 foram também clonados.
BR9708413-1A 1996-04-01 1997-04-01 Proteìnas de superfìcie de alto peso molecular de haemophilus não tipificável BR9708413A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/617,697 US5977336A (en) 1993-03-16 1996-04-01 High molecular weight surface proteins of non-typeable haemophilus
PCT/US1997/004707 WO1997036914A1 (en) 1996-04-01 1997-04-01 High molecular weight surface proteins of non-typeable haemophilus

Publications (1)

Publication Number Publication Date
BR9708413A true BR9708413A (pt) 2001-10-02

Family

ID=24474663

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708413-1A BR9708413A (pt) 1996-04-01 1997-04-01 Proteìnas de superfìcie de alto peso molecular de haemophilus não tipificável

Country Status (9)

Country Link
US (1) US5977336A (pt)
EP (1) EP0900232A4 (pt)
JP (1) JP2001503602A (pt)
AU (1) AU723159B2 (pt)
BR (1) BR9708413A (pt)
CA (1) CA2259133A1 (pt)
NZ (1) NZ332322A (pt)
RU (1) RU2206610C2 (pt)
WO (1) WO1997036914A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9201331D0 (sv) * 1992-04-28 1992-04-28 Hightech Receptor C O Active Protein l och hybridproteiner daerav
US6468765B1 (en) 1995-04-21 2002-10-22 Human Genome Sciences, Inc. Selected Haemophilus influenzae Rd polynucleotides and polypeptides
US6355450B1 (en) 1995-04-21 2002-03-12 Human Genome Sciences, Inc. Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof
JP3654512B2 (ja) * 1998-10-07 2005-06-02 アヴェンティス パスツール リミテッド 防御組換えｈａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ（インフルエンザ菌）高分子量タンパク質をコードする核酸分子、形質転換ベクター、形質転換菌株ならびにそれらを用いたタンパク質の生産方法
US6432669B1 (en) 1998-10-07 2002-08-13 Aventis Pasteur Limited Protective recombinant Haemophilus influenzae high molecular weight proteins
US6974581B1 (en) * 1998-12-15 2005-12-13 Aventis Pasteur Limited Multi-component vaccine comprising at least two antigens from haemophilus influenzae to protect against disease
US6342232B1 (en) * 1999-03-03 2002-01-29 Aventis Pasteur Limited Multi-component vaccine comprising at least three antigens to protect against disease cased by Haemophilus influenzae
US6391313B1 (en) 1999-07-15 2002-05-21 Aventis Pasteur Limited Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis
GB0102470D0 (en) * 2001-01-31 2001-03-14 Smithkline Beecham Biolog Novel compounds
US20040171805A1 (en) * 2001-03-13 2004-09-02 Joelle Thonnard Novel compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258029A (en) * 1979-04-23 1981-03-24 Connaught Laboratories Limited Synthetic adjuvants for stimulation of antigenic responses
US4952496A (en) * 1984-03-30 1990-08-28 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
DE3521994A1 (de) * 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US5194254A (en) * 1986-05-06 1993-03-16 Connaught Laboratories Limited Enhancement of antigen immunogenicity
DK0531497T3 (da) * 1991-04-02 1998-03-23 Biotech Australia Pty Ltd Orale indgivelsessystemer til mikropartikler
GB9205704D0 (en) * 1992-03-16 1992-04-29 Connaught Lab High molecular weight membrane proteins of non-typeable haemophilus
BR9406589A (pt) * 1993-03-16 1996-01-30 Univ St Louis Vacina contra doença causada por haemophilus influenzae não tipificável

Also Published As

Publication number Publication date
AU2587397A (en) 1997-10-22
NZ332322A (en) 2000-03-27
US5977336A (en) 1999-11-02
AU723159B2 (en) 2000-08-17
JP2001503602A (ja) 2001-03-21
EP0900232A4 (en) 2006-09-27
WO1997036914A1 (en) 1997-10-09
CA2259133A1 (en) 1997-10-09
EP0900232A1 (en) 1999-03-10
RU2206610C2 (ru) 2003-06-20

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Legal Events

Date Code Title Description
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART 36 DA LPI (LEI 9.279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.