BR9611851A - Molécula de ácido nucléico isolada e purificada, vetor de experessão recombinatória, célula hospedeira contendo um vetor de expressão recombina tório, proteìnas tbpa e tbpb isolada e purificadas, método para preparar uma protéina tbpa e tbpb, anti-corpo policlÈnico ou monoclÈnico, e vacinas assim obtidas - Google Patents
Molécula de ácido nucléico isolada e purificada, vetor de experessão recombinatória, célula hospedeira contendo um vetor de expressão recombina tório, proteìnas tbpa e tbpb isolada e purificadas, método para preparar uma protéina tbpa e tbpb, anti-corpo policlÈnico ou monoclÈnico, e vacinas assim obtidasInfo
- Publication number
- BR9611851A BR9611851A BR9611851-2A BR9611851A BR9611851A BR 9611851 A BR9611851 A BR 9611851A BR 9611851 A BR9611851 A BR 9611851A BR 9611851 A BR9611851 A BR 9611851A
- Authority
- BR
- Brazil
- Prior art keywords
- tbpa
- isolated
- vector
- tbpb
- purified
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 8
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000003259 recombinant expression Methods 0.000 title 1
- 102000004338 Transferrin Human genes 0.000 abstract 2
- 108090000901 Transferrin Proteins 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 239000012581 transferrin Substances 0.000 abstract 2
- CWPKTBMRVATCBL-UHFFFAOYSA-N 3-[1-[1-[(2-methylphenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1h-benzimidazol-2-one Chemical compound CC1=CC=CC=C1CN1CCC(N2CCC(CC2)N2C(NC3=CC=CC=C32)=O)CC1 CWPKTBMRVATCBL-UHFFFAOYSA-N 0.000 abstract 1
- 241001293418 Mannheimia haemolytica Species 0.000 abstract 1
- 102000010912 Transferrin-Binding Proteins Human genes 0.000 abstract 1
- 108010062476 Transferrin-Binding Proteins Proteins 0.000 abstract 1
- 102100029290 Transthyretin Human genes 0.000 abstract 1
- 108050000089 Transthyretin Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"MOLéCULA DE áCIDO NUCLéICO ISOLADA E PURIFICADA, VETOR DE EXPRESSãO RECOMBINATóRIO, CéLULA HOSPEDEIRA CONTENDO UM VETOR DE EXPRESSãO RECOMBINATóRIO, PROTEìNAS TBpA E TBpB ISOLADAS E PURIFICADAS, MéTODO PARA PREPARAR UMA PROTEìNA TBpA E TBpB, ANTI-CORPO POLICLONICO OU MONOCLONICO, VACINAS ASSIM OBTIDAS", compreendendo proteínas de ligação Transferrina da Pasteurella Haemolytica e moléculas de ácido nucléico que codificam as proteínas são mostradas: anticorpos contra as proteínas são mostrados: a invenção também refere-se a vacinas contendo as proteínas da invenção: a invenção também contém métodos para identificar substâncias que efetuam a ligação da transferrina para as proteínas e métodos para visualizar antagonistas da ligação de proteínas e transferrina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US856995P | 1995-12-01 | 1995-12-01 | |
| CA002164274A CA2164274A1 (en) | 1995-12-01 | 1995-12-01 | Transferrin binding proteins of pasteurella haemolytica and vaccines containing same |
| PCT/CA1996/000791 WO1997020934A1 (en) | 1995-12-01 | 1996-11-29 | Transferrin binding proteins of pasteurella haemolytica and vacc ines containing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9611851A true BR9611851A (pt) | 1999-12-28 |
Family
ID=25678245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9611851-2A BR9611851A (pt) | 1995-12-01 | 1996-11-29 | Molécula de ácido nucléico isolada e purificada, vetor de experessão recombinatória, célula hospedeira contendo um vetor de expressão recombina tório, proteìnas tbpa e tbpb isolada e purificadas, método para preparar uma protéina tbpa e tbpb, anti-corpo policlÈnico ou monoclÈnico, e vacinas assim obtidas |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0863986A1 (pt) |
| JP (1) | JP2000502249A (pt) |
| CN (1) | CN1219969A (pt) |
| BR (1) | BR9611851A (pt) |
| NZ (1) | NZ322415A (pt) |
| WO (1) | WO1997020934A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6391316B1 (en) * | 1999-03-10 | 2002-05-21 | University Of Saskatchewan | Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use |
| GB0007433D0 (en) * | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Recombinant transferrin binding proteins |
| US10149900B2 (en) | 2013-12-02 | 2018-12-11 | Engineered Antigens Inc. | Immunogenic compositions and vaccines derived from bacterial surface receptor proteins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292869A (en) * | 1989-04-27 | 1994-03-08 | The Board Of Governors Of The University | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
| ES2270420T3 (es) * | 1993-11-08 | 2007-04-01 | Sanofi Pasteur Limited | Genes receptores de la transferrina de haemophilus. |
| WO1995025742A1 (en) * | 1994-03-22 | 1995-09-28 | Pfizer Inc. | Pasteurellaceae antigens and related vaccines |
-
1996
- 1996-11-29 CN CN96199846A patent/CN1219969A/zh active Pending
- 1996-11-29 BR BR9611851-2A patent/BR9611851A/pt not_active Application Discontinuation
- 1996-11-29 EP EP96938893A patent/EP0863986A1/en not_active Withdrawn
- 1996-11-29 NZ NZ322415A patent/NZ322415A/en unknown
- 1996-11-29 JP JP9520816A patent/JP2000502249A/ja not_active Withdrawn
- 1996-11-29 WO PCT/CA1996/000791 patent/WO1997020934A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0863986A1 (en) | 1998-09-16 |
| NZ322415A (en) | 2000-02-28 |
| WO1997020934A1 (en) | 1997-06-12 |
| CN1219969A (zh) | 1999-06-16 |
| JP2000502249A (ja) | 2000-02-29 |
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| BR9611851A (pt) | Molécula de ácido nucléico isolada e purificada, vetor de experessão recombinatória, célula hospedeira contendo um vetor de expressão recombina tório, proteìnas tbpa e tbpb isolada e purificadas, método para preparar uma protéina tbpa e tbpb, anti-corpo policlÈnico ou monoclÈnico, e vacinas assim obtidas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Owner name: UNIVERSITY OF GUELPH (CA), UNIVERSITY TECHNOLOGIES |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |