BR9611851A - Isolated and purified nucleic acid molecule, recombinatory experiment vector, host cell containing a vector of recombinant expression, tbpa and tbpb proteins isolated and purified, method for preparing a tbpa and tbpb protein, polyclinic or monoclinic antibody, and vaccines as well obtained - Google Patents
Isolated and purified nucleic acid molecule, recombinatory experiment vector, host cell containing a vector of recombinant expression, tbpa and tbpb proteins isolated and purified, method for preparing a tbpa and tbpb protein, polyclinic or monoclinic antibody, and vaccines as well obtainedInfo
- Publication number
- BR9611851A BR9611851A BR9611851-2A BR9611851A BR9611851A BR 9611851 A BR9611851 A BR 9611851A BR 9611851 A BR9611851 A BR 9611851A BR 9611851 A BR9611851 A BR 9611851A
- Authority
- BR
- Brazil
- Prior art keywords
- tbpa
- isolated
- vector
- tbpb
- purified
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 8
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000003259 recombinant expression Methods 0.000 title 1
- 102000004338 Transferrin Human genes 0.000 abstract 2
- 108090000901 Transferrin Proteins 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 239000012581 transferrin Substances 0.000 abstract 2
- CWPKTBMRVATCBL-UHFFFAOYSA-N 3-[1-[1-[(2-methylphenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1h-benzimidazol-2-one Chemical compound CC1=CC=CC=C1CN1CCC(N2CCC(CC2)N2C(NC3=CC=CC=C32)=O)CC1 CWPKTBMRVATCBL-UHFFFAOYSA-N 0.000 abstract 1
- 241001293418 Mannheimia haemolytica Species 0.000 abstract 1
- 102000010912 Transferrin-Binding Proteins Human genes 0.000 abstract 1
- 108010062476 Transferrin-Binding Proteins Proteins 0.000 abstract 1
- 102100029290 Transthyretin Human genes 0.000 abstract 1
- 108050000089 Transthyretin Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"MOLéCULA DE áCIDO NUCLéICO ISOLADA E PURIFICADA, VETOR DE EXPRESSãO RECOMBINATóRIO, CéLULA HOSPEDEIRA CONTENDO UM VETOR DE EXPRESSãO RECOMBINATóRIO, PROTEìNAS TBpA E TBpB ISOLADAS E PURIFICADAS, MéTODO PARA PREPARAR UMA PROTEìNA TBpA E TBpB, ANTI-CORPO POLICLONICO OU MONOCLONICO, VACINAS ASSIM OBTIDAS", compreendendo proteínas de ligação Transferrina da Pasteurella Haemolytica e moléculas de ácido nucléico que codificam as proteínas são mostradas: anticorpos contra as proteínas são mostrados: a invenção também refere-se a vacinas contendo as proteínas da invenção: a invenção também contém métodos para identificar substâncias que efetuam a ligação da transferrina para as proteínas e métodos para visualizar antagonistas da ligação de proteínas e transferrina."ISOLATED AND PURIFIED NUCLEIC ACID MOLECULE, RECOMBINATORY EXPRESSION VECTOR, HOSTING CELL CONTAINING A RECOMBINATORY EXPRESSION VECTOR, ISOLATED AND PURIFIED TBPA AND TBPB PROTEINS, PROTECTED AND PROTECTED ETHOSPHERE, PREPARED TO PREPARING ", comprising Transferrin binding proteins from Pasteurella Haemolytica and nucleic acid molecules encoding proteins are shown: antibodies against proteins are shown: the invention also relates to vaccines containing the proteins of the invention: the invention also contains methods for identifying substances that effect transferrin binding to proteins and methods for visualizing protein binding and transferrin antagonists.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US856995P | 1995-12-01 | 1995-12-01 | |
| CA002164274A CA2164274A1 (en) | 1995-12-01 | 1995-12-01 | Transferrin binding proteins of pasteurella haemolytica and vaccines containing same |
| PCT/CA1996/000791 WO1997020934A1 (en) | 1995-12-01 | 1996-11-29 | Transferrin binding proteins of pasteurella haemolytica and vacc ines containing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9611851A true BR9611851A (en) | 1999-12-28 |
Family
ID=25678245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9611851-2A BR9611851A (en) | 1995-12-01 | 1996-11-29 | Isolated and purified nucleic acid molecule, recombinatory experiment vector, host cell containing a vector of recombinant expression, tbpa and tbpb proteins isolated and purified, method for preparing a tbpa and tbpb protein, polyclinic or monoclinic antibody, and vaccines as well obtained |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0863986A1 (en) |
| JP (1) | JP2000502249A (en) |
| CN (1) | CN1219969A (en) |
| BR (1) | BR9611851A (en) |
| NZ (1) | NZ322415A (en) |
| WO (1) | WO1997020934A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6391316B1 (en) * | 1999-03-10 | 2002-05-21 | University Of Saskatchewan | Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use |
| GB0007433D0 (en) * | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Recombinant transferrin binding proteins |
| BR112016012285A2 (en) * | 2013-12-02 | 2017-09-26 | B Schryvers Anthony | immunogenic compositions and vaccines derived from bacterial surface receptor proteins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292869A (en) * | 1989-04-27 | 1994-03-08 | The Board Of Governors Of The University | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
| EP0728200B1 (en) * | 1993-11-08 | 2006-08-30 | Sanofi Pasteur Limited | Haemophilus transferrin receptor genes |
| CA2186121A1 (en) * | 1994-03-22 | 1995-09-28 | Robert Gerard Ankenbauer | Pasteurellaceae antigens and related vaccines |
-
1996
- 1996-11-29 NZ NZ322415A patent/NZ322415A/en unknown
- 1996-11-29 EP EP96938893A patent/EP0863986A1/en not_active Withdrawn
- 1996-11-29 JP JP9520816A patent/JP2000502249A/en not_active Withdrawn
- 1996-11-29 WO PCT/CA1996/000791 patent/WO1997020934A1/en not_active Application Discontinuation
- 1996-11-29 BR BR9611851-2A patent/BR9611851A/en not_active Application Discontinuation
- 1996-11-29 CN CN96199846A patent/CN1219969A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997020934A1 (en) | 1997-06-12 |
| NZ322415A (en) | 2000-02-28 |
| EP0863986A1 (en) | 1998-09-16 |
| JP2000502249A (en) | 2000-02-29 |
| CN1219969A (en) | 1999-06-16 |
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| BR9611851A (en) | Isolated and purified nucleic acid molecule, recombinatory experiment vector, host cell containing a vector of recombinant expression, tbpa and tbpb proteins isolated and purified, method for preparing a tbpa and tbpb protein, polyclinic or monoclinic antibody, and vaccines as well obtained |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Owner name: UNIVERSITY OF GUELPH (CA), UNIVERSITY TECHNOLOGIES |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |