BR9609847A - Derivados de N-(4-Benzila-substituída)-2-aminolactam - Google Patents
Derivados de N-(4-Benzila-substituída)-2-aminolactamInfo
- Publication number
- BR9609847A BR9609847A BR9609847A BR9609847A BR9609847A BR 9609847 A BR9609847 A BR 9609847A BR 9609847 A BR9609847 A BR 9609847A BR 9609847 A BR9609847 A BR 9609847A BR 9609847 A BR9609847 A BR 9609847A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- benzyl
- substituted
- sec
- date
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515411.8A GB9515411D0 (en) | 1995-07-27 | 1995-07-27 | N-(4-substituted-benzyl)-2-aminolactam derivatives |
| PCT/EP1996/002962 WO1997005111A1 (en) | 1995-07-27 | 1996-07-05 | N-(4-substituted-benzyl)-2-aminolactam derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9609847A true BR9609847A (pt) | 1999-03-09 |
Family
ID=10778351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9609847A BR9609847A (pt) | 1995-07-27 | 1996-07-05 | Derivados de N-(4-Benzila-substituída)-2-aminolactam |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5912242A (pt) |
| EP (1) | EP0842152B1 (pt) |
| JP (1) | JP3939755B2 (pt) |
| AT (1) | ATE199013T1 (pt) |
| AU (1) | AU6611696A (pt) |
| BR (1) | BR9609847A (pt) |
| CA (1) | CA2226886C (pt) |
| DE (1) | DE69611728T2 (pt) |
| ES (1) | ES2154830T3 (pt) |
| GB (1) | GB9515411D0 (pt) |
| IL (1) | IL122706A0 (pt) |
| WO (1) | WO1997005111A1 (pt) |
| ZA (1) | ZA965997B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| CA2746824A1 (en) | 1999-08-16 | 2001-01-22 | Revaax Pharmaceuticals, Llc | Neurotherapeutic composition and method |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| EP1423168B1 (en) | 2001-09-03 | 2006-02-08 | Newron Pharmaceuticals S.p.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| EP1524267A1 (en) | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Substituted benzylaminoalkylene heterocycles |
| EP1533298A1 (en) * | 2003-11-21 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | 3-aminopyrrolidone derivatives |
| EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| EP1870097A1 (en) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
| US7629351B2 (en) | 2006-07-28 | 2009-12-08 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino) pyrrolidin-1-yl)cyclohexyl)acetamide and other modulators of chemokine receptor activity, crystalline forms and process |
| US7687508B2 (en) | 2006-07-28 | 2010-03-30 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7671062B2 (en) | 2006-07-28 | 2010-03-02 | Bristol-Myers Squibb Company | Modulators of chemokine receptor activity, crystalline forms and process |
| WO2010127125A1 (en) * | 2009-04-29 | 2010-11-04 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
| US8383812B2 (en) | 2009-10-13 | 2013-02-26 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU518986B2 (en) * | 1977-10-11 | 1981-10-29 | Takeda Chemical Industries Ltd. | Lactams |
| US4719207A (en) * | 1984-06-25 | 1988-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | CNS active substituted azetidinone compounds |
| GB8823605D0 (en) * | 1988-10-07 | 1988-11-16 | Merck Sharp & Dohme | Therapeutic agents |
-
1995
- 1995-07-27 GB GBGB9515411.8A patent/GB9515411D0/en active Pending
-
1996
- 1996-07-05 ES ES96925667T patent/ES2154830T3/es not_active Expired - Lifetime
- 1996-07-05 AT AT96925667T patent/ATE199013T1/de not_active IP Right Cessation
- 1996-07-05 JP JP50714897A patent/JP3939755B2/ja not_active Expired - Lifetime
- 1996-07-05 DE DE69611728T patent/DE69611728T2/de not_active Expired - Lifetime
- 1996-07-05 CA CA002226886A patent/CA2226886C/en not_active Expired - Lifetime
- 1996-07-05 US US08/981,493 patent/US5912242A/en not_active Expired - Lifetime
- 1996-07-05 EP EP96925667A patent/EP0842152B1/en not_active Expired - Lifetime
- 1996-07-05 IL IL12270696A patent/IL122706A0/xx unknown
- 1996-07-05 AU AU66116/96A patent/AU6611696A/en not_active Abandoned
- 1996-07-05 BR BR9609847A patent/BR9609847A/pt not_active Application Discontinuation
- 1996-07-05 WO PCT/EP1996/002962 patent/WO1997005111A1/en active IP Right Grant
- 1996-07-15 ZA ZA965997A patent/ZA965997B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5912242A (en) | 1999-06-15 |
| IL122706A0 (en) | 1998-08-16 |
| EP0842152B1 (en) | 2001-01-31 |
| ZA965997B (en) | 1997-01-31 |
| CA2226886C (en) | 2007-01-30 |
| DE69611728D1 (de) | 2001-03-08 |
| DE69611728T2 (de) | 2001-05-10 |
| CA2226886A1 (en) | 1997-02-13 |
| EP0842152A1 (en) | 1998-05-20 |
| AU6611696A (en) | 1997-02-26 |
| ATE199013T1 (de) | 2001-02-15 |
| JP3939755B2 (ja) | 2007-07-04 |
| ES2154830T3 (es) | 2001-04-16 |
| WO1997005111A1 (en) | 1997-02-13 |
| GB9515411D0 (en) | 1995-09-27 |
| JPH11509848A (ja) | 1999-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9609847A (pt) | Derivados de N-(4-Benzila-substituída)-2-aminolactam | |
| UA44254C2 (uk) | Похідні 4-(заміщеного феніламіно)хіназоліну, спосіб їх одержання, спосіб лікування і фармацевтична композиція | |
| NO963850L (no) | Heterosykliske forbindelser, deres fremstilling og anvendelse | |
| MXPA02001340A (es) | Compuestos novedosos 1,4-benzodiazepina y derivados de los mismos. | |
| NO954072D0 (no) | Vannopplöselige camptotecinderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler | |
| FI972434A (fi) | Lamotrigiiniä sisältävä farmaseuttinen koostumus | |
| FI973221A0 (fi) | 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina | |
| ATE233246T1 (de) | Hydantoinderivate als zwischenprodukte für pharmazeutische wirkstoffe | |
| NO980296L (no) | Forbedrede terapeutiske midler | |
| DK0891341T3 (da) | 1,3,4-Oxadiazinderivater samt deres anvendelse som pesticider | |
| ATE165101T1 (de) | Basische prolinamid derivate von ge2270 und ge2270-ahnlichten antibiotika | |
| BR9610175A (pt) | Composto processo de preparação do composto composição farmacêutica e utilização do composto | |
| NZ320522A (en) | Piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same and a process for the preparation of the compounds | |
| DK0805817T3 (da) | Thiolderivater med metallopeptidaseinhiberende aktivitet | |
| ES2137665T3 (es) | Nuevos derivados de piridina o piridazina, procedimientos para su preparacion, y medicamentos que contienen estos compuestos. | |
| TR200402685T4 (tr) | Merkezi sinir sistemi üzerine etki eden siklobüta-indol karboksamid türevleri, bunların hazırlanma yöntemleri ve bunları içeren farmasötik bileşimler. | |
| DK0815109T3 (da) | Fremgangsmåde til fremstilling af estere af anhydroecgonin | |
| ZA955052B (en) | Pyrrolidine derivatives their preparation and compositions containing them | |
| CA2241788A1 (fr) | Nouveaux derives de n-(arylsulfonyl)aminoacides, leur procede de preparation et compositions pharmaceutiques en contenant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law |