BR9106665A - Derivados de quinuclidina - Google Patents

Derivados de quinuclidina

Info

Publication number
BR9106665A
BR9106665A BR919106665A BR9106665A BR9106665A BR 9106665 A BR9106665 A BR 9106665A BR 919106665 A BR919106665 A BR 919106665A BR 9106665 A BR9106665 A BR 9106665A BR 9106665 A BR9106665 A BR 9106665A
Authority
BR
Brazil
Prior art keywords
quinuclidine derivatives
quinuclidine
derivatives
migraine
antagonists
Prior art date
Application number
BR919106665A
Other languages
English (en)
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9106665A publication Critical patent/BR9106665A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
BR919106665A 1990-07-23 1991-05-14 Derivados de quinuclidina BR9106665A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55744290A 1990-07-23 1990-07-23
PCT/US1991/003369 WO1992001688A1 (en) 1990-07-23 1991-05-14 Quinuclidine derivatives

Publications (1)

Publication Number Publication Date
BR9106665A true BR9106665A (pt) 1993-06-08

Family

ID=24225412

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919106665A BR9106665A (pt) 1990-07-23 1991-05-14 Derivados de quinuclidina

Country Status (25)

Country Link
US (5) US5422354A (pt)
EP (1) EP0540526B1 (pt)
JP (1) JP2514137B2 (pt)
CN (1) CN1058405A (pt)
AT (1) ATE116317T1 (pt)
AU (1) AU660416B2 (pt)
BR (1) BR9106665A (pt)
CA (1) CA2086434C (pt)
DE (1) DE69106365T2 (pt)
DK (1) DK0540526T3 (pt)
ES (1) ES2065691T3 (pt)
FI (1) FI114473B (pt)
GR (1) GR3015144T3 (pt)
HU (1) HUT62584A (pt)
IE (1) IE65000B1 (pt)
IL (1) IL98860A (pt)
MX (1) MX9100308A (pt)
MY (1) MY107157A (pt)
NO (1) NO302172B1 (pt)
NZ (1) NZ239063A (pt)
PL (1) PL167568B1 (pt)
PT (1) PT98393B (pt)
WO (1) WO1992001688A1 (pt)
YU (1) YU128091A (pt)
ZA (1) ZA915727B (pt)

Families Citing this family (73)

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US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
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CN1067069C (zh) * 1996-05-13 2001-06-13 曾尼卡有限公司 作为杀虫剂的双环胺
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GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
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EA199900502A1 (ru) 1996-11-26 2000-02-28 Зенека Лимитед 8-азабицикло[3.2.1]октан-, 8-азабицикло[3.2.1]окт-6-ен-, 9-азабицикло[3.3.1]нонан-, 9-аза-3-оксабицикло[3.3.1]нонан- и 9-аза-3-тиабицикло[3.3.1]нонанпроизводные, их получение и их применение в качестве инсектицидов
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US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
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KR20120023072A (ko) 2009-05-12 2012-03-12 브리스톨-마이어스 스큅 컴퍼니 （Ｓ）-7-（〔1,2,4〕트리아졸〔1,5-ａ〕피리딘-6-일）-4-（3,4-디클로로페닐）-1,2,3,4-테트라하이드로이소퀴놀린의 결정형 및 이의 용도
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
BR112012008849A2 (pt) 2009-10-14 2015-09-22 Schering Corp composto, composição farmacêutica, e, uso de um composto
EP2584903B1 (en) 2010-06-24 2018-10-24 Merck Sharp & Dohme Corp. Novel heterocyclic compounds as erk inhibitors
JP6043285B2 (ja) 2010-08-02 2016-12-14 サーナ・セラピューティクス・インコーポレイテッドＳｉｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 低分子干渉核酸（ｓｉＮＡ）を用いたカテニン（カドヘリン結合型タンパク質）β１（ＣＴＮＮＢ１）遺伝子発現のＲＮＡ干渉媒介性阻害
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Family Cites Families (8)

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US2455949A (en) * 1947-06-02 1948-12-14 Parke Davis & Co Dialkylaminoalkyl benzahydryl ethers and salts thereof
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
GB1527489A (en) * 1976-08-05 1978-10-04 Andreu Sa Dr Amine compound
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MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
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DK0540526T3 (da) * 1990-07-23 1995-04-18 Pfizer Quinuclidinderivater

Also Published As

Publication number Publication date
DK0540526T3 (da) 1995-04-18
ZA915727B (en) 1993-02-24
US5641786A (en) 1997-06-24
PT98393B (pt) 1999-01-29
EP0540526B1 (en) 1994-12-28
AU660416B2 (en) 1995-06-29
ATE116317T1 (de) 1995-01-15
FI114473B (fi) 2004-10-29
US5698568A (en) 1997-12-16
CN1058405A (zh) 1992-02-05
PL167568B1 (pl) 1995-09-30
MX9100308A (es) 1992-02-28
NO930222L (no) 1993-01-22
YU128091A (sh) 1994-01-20
GR3015144T3 (en) 1995-05-31
MY107157A (en) 1995-09-30
US5422354A (en) 1995-06-06
JPH05507687A (ja) 1993-11-04
NO930222D0 (no) 1993-01-22
DE69106365D1 (de) 1995-02-09
NZ239063A (en) 1995-09-26
AU7894891A (en) 1992-02-18
US5821248A (en) 1998-10-13
CA2086434C (en) 1998-09-22
FI930262A0 (fi) 1993-01-22
EP0540526A1 (en) 1993-05-12
IE912560A1 (en) 1992-01-29
FI930262A (fi) 1993-01-22
IL98860A (en) 1995-11-27
CA2086434A1 (en) 1992-01-24
ES2065691T3 (es) 1995-02-16
JP2514137B2 (ja) 1996-07-10
NO302172B1 (no) 1998-02-02
HU9300188D0 (en) 1993-04-28
IL98860A0 (en) 1992-07-15
PT98393A (pt) 1992-05-29
DE69106365T2 (de) 1995-05-04
HUT62584A (en) 1993-05-28
WO1992001688A1 (en) 1992-02-06
IE65000B1 (en) 1995-10-04
US5854256A (en) 1998-12-29

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal