BR112022011255A2 - Imagens microscópicas sem foco de uma amostra - Google Patents
Imagens microscópicas sem foco de uma amostraInfo
- Publication number
- BR112022011255A2 BR112022011255A2 BR112022011255A BR112022011255A BR112022011255A2 BR 112022011255 A2 BR112022011255 A2 BR 112022011255A2 BR 112022011255 A BR112022011255 A BR 112022011255A BR 112022011255 A BR112022011255 A BR 112022011255A BR 112022011255 A2 BR112022011255 A2 BR 112022011255A2
- Authority
- BR
- Brazil
- Prior art keywords
- sample
- microscope
- focus
- level
- focal plane
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1493—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1497—Particle shape
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10056—Microscopic image
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Quality & Reliability (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Radiology & Medical Imaging (AREA)
- Theoretical Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Optics & Photonics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Signal Processing (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Microscoopes, Condenser (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Focus Adjustment (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Image Analysis (AREA)
Abstract
IMAGENS MICROSCÓPICAS SEM FOCO DE UMA AMOSTRA. Trata-se de aparelho e métodos que são descritos para o uso com uma amostra corporal que contém células. Um microscópio (24) é focado, de modo que um plano focal do microscópio (24) coincida pelo menos aproximadamente com um nível no qual pelo menos algumas células que pertencem à amostra são pelo menos parcialmente dispostas. Pelo menos uma imagem microscópica com foco da amostra, enquanto o plano focal do microscópio (24) coincide aproximadamente com o nível. O microscópio (24) é focado de modo que o plano focal do microscópio seja deslocado com relação ao nível, pelo menos uma imagem microscópica sem foco da amostra é adquirida, enquanto o plano focal do microscópio (24) é deslocado com relação ao nível. Uma propriedade de pelo menos uma porção da amostra é determinada, pelo menos parcialmente com base nas imagens com foco e sem foco. Outras aplicações também são descritas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962946985P | 2019-12-12 | 2019-12-12 | |
| US202063048692P | 2020-07-07 | 2020-07-07 | |
| PCT/IB2020/061728 WO2021116957A1 (en) | 2019-12-12 | 2020-12-10 | Off-focus microscopic images of a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022011255A2 true BR112022011255A2 (pt) | 2022-09-06 |
Family
ID=73856204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022011255A BR112022011255A2 (pt) | 2019-12-12 | 2020-12-10 | Imagens microscópicas sem foco de uma amostra |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230011382A1 (pt) |
| EP (1) | EP4073491A1 (pt) |
| JP (1) | JP2023506417A (pt) |
| CN (1) | CN114829900A (pt) |
| AU (1) | AU2020402284A1 (pt) |
| BR (1) | BR112022011255A2 (pt) |
| CA (1) | CA3160692A1 (pt) |
| MX (1) | MX2022007121A (pt) |
| WO (1) | WO2021116957A1 (pt) |
| ZA (1) | ZA202206312B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022009104A2 (en) | 2020-07-07 | 2022-01-13 | S.D. Sight Diagnostics Ltd | Focusing a microscope using fluorescent images |
| WO2023144713A1 (en) | 2022-01-25 | 2023-08-03 | S.D. Sight Diagnostics Ltd | Sample carrier for use with a bodily sample |
| GB202218615D0 (en) | 2022-12-12 | 2023-01-25 | S D Sight Diagnostics Ltd | System and method for analyzing bodily samples |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5040191B2 (ja) * | 2006-06-29 | 2012-10-03 | 富士通株式会社 | マイクロインジェクション装置及び自動焦点調整方法 |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| WO2013098821A1 (en) | 2011-12-29 | 2013-07-04 | Parasight Ltd. | Methods and systems for detecting a pathogen in a biological sample |
| JP5464244B2 (ja) * | 2012-08-24 | 2014-04-09 | 富士ゼロックス株式会社 | 画像処理装置、プログラム及び画像処理システム |
| EP2999988A4 (en) | 2013-05-23 | 2017-01-11 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for obtaining a monolayer of cells, for use specifically for diagnosis |
| US10831013B2 (en) | 2013-08-26 | 2020-11-10 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| EP3186778B1 (en) | 2014-08-27 | 2023-01-11 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| CN108474934B (zh) | 2015-09-17 | 2022-01-18 | 思迪赛特诊断有限公司 | 用于检测身体样本中实体的方法和设备 |
| CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
| CA3022770A1 (en) | 2016-05-11 | 2017-11-16 | S.D. Sight Diagnostics Ltd | Performing optical measurements on a sample |
| WO2017195205A1 (en) | 2016-05-11 | 2017-11-16 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
| US11921272B2 (en) | 2017-11-14 | 2024-03-05 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
-
2020
- 2020-12-10 EP EP20828312.7A patent/EP4073491A1/en active Pending
- 2020-12-10 JP JP2022534230A patent/JP2023506417A/ja active Pending
- 2020-12-10 AU AU2020402284A patent/AU2020402284A1/en active Pending
- 2020-12-10 US US17/783,831 patent/US20230011382A1/en active Pending
- 2020-12-10 WO PCT/IB2020/061728 patent/WO2021116957A1/en unknown
- 2020-12-10 CN CN202080085489.0A patent/CN114829900A/zh active Pending
- 2020-12-10 MX MX2022007121A patent/MX2022007121A/es unknown
- 2020-12-10 CA CA3160692A patent/CA3160692A1/en active Pending
- 2020-12-10 BR BR112022011255A patent/BR112022011255A2/pt unknown
-
2022
- 2022-06-07 ZA ZA2022/06312A patent/ZA202206312B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021116957A1 (en) | 2021-06-17 |
| US20230011382A1 (en) | 2023-01-12 |
| CA3160692A1 (en) | 2021-06-17 |
| ZA202206312B (en) | 2023-02-22 |
| MX2022007121A (es) | 2022-07-11 |
| EP4073491A1 (en) | 2022-10-19 |
| CN114829900A (zh) | 2022-07-29 |
| JP2023506417A (ja) | 2023-02-16 |
| AU2020402284A1 (en) | 2022-06-02 |
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