BR112021022089A2 - Materiais e métodos para modulação da imunidade mediada por células t - Google Patents

Materiais e métodos para modulação da imunidade mediada por células t

Info

Publication number
BR112021022089A2
BR112021022089A2 BR112021022089A BR112021022089A BR112021022089A2 BR 112021022089 A2 BR112021022089 A2 BR 112021022089A2 BR 112021022089 A BR112021022089 A BR 112021022089A BR 112021022089 A BR112021022089 A BR 112021022089A BR 112021022089 A2 BR112021022089 A2 BR 112021022089A2
Authority
BR
Brazil
Prior art keywords
methods
antibodies
modulating
cell
materials
Prior art date
Application number
BR112021022089A
Other languages
English (en)
Inventor
S Grewal Iqbal
Rajkumar Ganesan
Sanjaya Singh
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of BR112021022089A2 publication Critical patent/BR112021022089A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

materiais e métodos para modulação da imunidade mediada por células t. são descritos anticorpos anti-trgv9 ou fragmento de ligação a antígeno dos mesmos. são descritos, também, ácidos nucleicos que codificam os anticorpos, composições que compreendem os anticorpos, métodos de produção dos anticorpos e métodos de uso dos anticorpos para tratamento ou prevenção de doenças, como câncer.
BR112021022089A 2019-05-08 2020-05-07 Materiais e métodos para modulação da imunidade mediada por células t BR112021022089A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962844959P 2019-05-08 2019-05-08
US201962844970P 2019-05-08 2019-05-08
US201962844995P 2019-05-08 2019-05-08
US201962844966P 2019-05-08 2019-05-08
US201962844976P 2019-05-08 2019-05-08
PCT/US2020/031749 WO2020227457A1 (en) 2019-05-08 2020-05-07 Materials and methods for modulating t cell mediated immunity

Publications (1)

Publication Number Publication Date
BR112021022089A2 true BR112021022089A2 (pt) 2022-02-08

Family

ID=73051172

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021022089A BR112021022089A2 (pt) 2019-05-08 2020-05-07 Materiais e métodos para modulação da imunidade mediada por células t

Country Status (21)

Country Link
US (2) US11667712B2 (pt)
EP (1) EP3965818A4 (pt)
JP (1) JP2022533538A (pt)
KR (1) KR20220017892A (pt)
CN (1) CN113966231A (pt)
AU (1) AU2020267504A1 (pt)
BR (1) BR112021022089A2 (pt)
CA (1) CA3139508A1 (pt)
CL (1) CL2021002905A1 (pt)
CO (1) CO2021015998A2 (pt)
CR (1) CR20210548A (pt)
DO (1) DOP2021000229A (pt)
EC (1) ECSP21087921A (pt)
IL (1) IL287817A (pt)
JO (1) JOP20210297A1 (pt)
MA (1) MA55903A (pt)
MX (1) MX2021013532A (pt)
PE (1) PE20220763A1 (pt)
SG (1) SG11202112021QA (pt)
TW (1) TW202108618A (pt)
WO (1) WO2020227457A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210284731A1 (en) * 2020-03-13 2021-09-16 Janssen Biotech, Inc. Methods and materials for modulating an immune response
JP2024507937A (ja) 2021-02-26 2024-02-21 ラヴァ・セラピューティクス・エヌ・ヴイ Ｃｄ１２３及びガンマデルタｔ細胞受容体に結合する抗体

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EP1461082A4 (en) 2001-12-03 2006-06-28 Abgenix Inc ANTIBODIES AGAINST THE TUMOR ANTIGEN OF CARBON IX ANHYDRASE (CA IX)
JP2008511337A (ja) 2004-09-02 2008-04-17 ジェネンテック・インコーポレーテッド ヘテロ多量体分子
ES2592271T3 (es) 2005-03-31 2016-11-29 Chugai Seiyaku Kabushiki Kaisha Métodos de producción de polipéptidos mediante la regulación de la asociación de los polipéptidos
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
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CN116390950A (zh) 2020-10-28 2023-07-04 詹森生物科技公司 用于调节δγ链介导的免疫的组合物和方法

Also Published As

Publication number Publication date
EP3965818A4 (en) 2023-05-31
JP2022533538A (ja) 2022-07-25
ECSP21087921A (es) 2022-01-31
AU2020267504A1 (en) 2021-12-02
US11667712B2 (en) 2023-06-06
KR20220017892A (ko) 2022-02-14
DOP2021000229A (es) 2022-07-31
US20240150464A1 (en) 2024-05-09
MA55903A (fr) 2022-03-16
CL2021002905A1 (es) 2022-06-17
SG11202112021QA (en) 2021-11-29
MX2021013532A (es) 2022-02-11
PE20220763A1 (es) 2022-05-16
IL287817A (en) 2022-01-01
TW202108618A (zh) 2021-03-01
US20210032338A1 (en) 2021-02-04
CO2021015998A2 (es) 2021-12-10
EP3965818A1 (en) 2022-03-16
CN113966231A (zh) 2022-01-21
CR20210548A (es) 2022-02-11
CA3139508A1 (en) 2020-11-12
JOP20210297A1 (ar) 2023-01-30
WO2020227457A1 (en) 2020-11-12

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Legal Events

Date Code Title Description
B11U Patent application definitively rejected as a later application filed via pct claims it as a priority [chapter 11.21 patent gazette]

Free format text: ARQUIVADO DEFINITIVAMENTE ESTE PEDIDO DE PATENTE, UMA VEZ QUE FOI ADMITIDO NA FASE NACIONAL BRASILEIRA O PEDIDO (112022017142-0) QUE O REIVINDICA COMO PRIORIDADE.

B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]

Free format text: ANULACAO DO DESPACHO DE ARQUIVAMENTO DEFINITIVO DO PEDIDO (DESPACHO 11.21) POR TER SIDO INDEVIDO, TENDO EM VISTA A NECESSIDADE DE AVALIACAO DO CONTEUDO DOS PEDIDOS PELA AREA TECNICA.