BR112015015858A8 - composição farmacêutica de solução sólida, e, uso de uma composição farmacêutica - Google Patents

composição farmacêutica de solução sólida, e, uso de uma composição farmacêutica

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Publication number
BR112015015858A8
BR112015015858A8 BR112015015858A BR112015015858A BR112015015858A8 BR 112015015858 A8 BR112015015858 A8 BR 112015015858A8 BR 112015015858 A BR112015015858 A BR 112015015858A BR 112015015858 A BR112015015858 A BR 112015015858A BR 112015015858 A8 BR112015015858 A8 BR 112015015858A8
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
solid solution
pharmaceutical compositions
methods
solution pharmaceutical
Prior art date
Application number
BR112015015858A
Other languages
English (en)
Other versions
BR112015015858B1 (pt
BR112015015858A2 (pt
Inventor
Brew John
Robert Reiley Richard
Mark Bannister Robin
Caparrós-Wanderley Wilson
Original Assignee
Infirst Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infirst Healthcare Ltd filed Critical Infirst Healthcare Ltd
Publication of BR112015015858A2 publication Critical patent/BR112015015858A2/pt
Publication of BR112015015858A8 publication Critical patent/BR112015015858A8/pt
Publication of BR112015015858B1 publication Critical patent/BR112015015858B1/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61K31/12—Ketones
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Abstract

1 / 1 resumo “composiã‡ãƒo farmacãšutica de soluã‡ãƒo sã“lida” o presente relatã³rio descreve composiã§ãµes farmacãªuticas, mã©todos para preparar tais composiã§ãµes farmacãªuticas, e mã©todos e usos para tratar uma inflamaã§ã£o crã´nica e/ou uma doenã§a inflamatã³ria em um indivã­duo usando tais composiã§ãµes farmacãªuticas.
BR112015015858-7A 2013-01-14 2014-01-14 Uso de uma composição farmacêutica de solução sólida no tratamento de uma inflamação crônica BR112015015858B1 (pt)

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US201361752356P 2013-01-14 2013-01-14
US61/752,356 2013-01-14
US201361752309P 2013-02-04 2013-02-04
US61/752,309 2013-02-04
PCT/EP2014/050637 WO2014108573A1 (en) 2013-01-14 2014-01-14 Solid solution compositions and use in chronic inflammation

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BR112015015858-7A BR112015015858B1 (pt) 2013-01-14 2014-01-14 Uso de uma composição farmacêutica de solução sólida no tratamento de uma inflamação crônica
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