GB2331458B - Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine - Google Patents

Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine

Info

Publication number
GB2331458B
GB2331458B GB9725420A GB9725420A GB2331458B GB 2331458 B GB2331458 B GB 2331458B GB 9725420 A GB9725420 A GB 9725420A GB 9725420 A GB9725420 A GB 9725420A GB 2331458 B GB2331458 B GB 2331458B
Authority
GB
United Kingdom
Prior art keywords
solubilising
encapsulation
systems
soft gelatine
stable solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9725420A
Other versions
GB2331458A (en
GB2331458A9 (en
GB9725420D0 (en
Inventor
Gursharan Singh Moonga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of GB2331458A9 publication Critical patent/GB2331458A9/en
Application filed by Individual filed Critical Individual
Priority to GB9725420A priority Critical patent/GB2331458B/en
Publication of GB9725420D0 publication Critical patent/GB9725420D0/en
Publication of GB2331458A publication Critical patent/GB2331458A/en
Application granted granted Critical
Publication of GB2331458B publication Critical patent/GB2331458B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
GB9725420A 1997-11-21 1997-11-21 Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine Expired - Fee Related GB2331458B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9725420A GB2331458B (en) 1997-11-21 1997-11-21 Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9725420A GB2331458B (en) 1997-11-21 1997-11-21 Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine

Publications (4)

Publication Number Publication Date
GB2331458A9 GB2331458A9 (en)
GB9725420D0 GB9725420D0 (en) 1998-01-28
GB2331458A GB2331458A (en) 1999-05-26
GB2331458B true GB2331458B (en) 2002-07-31

Family

ID=10822948

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9725420A Expired - Fee Related GB2331458B (en) 1997-11-21 1997-11-21 Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine

Country Status (1)

Country Link
GB (1) GB2331458B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2809958B1 (en) * 2000-06-08 2005-01-14 Crinex Lab LIQUID-LIKE PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF AN ACTIVE INGREDIENT, WITH UNDEMPLICABLE TASTE, INCLUDING BITTERY TASTE
WO2002069936A2 (en) * 2001-03-02 2002-09-12 Dr. Reddy's Laboratories Ltd. Pharmaceutical composition of ibuprofen
EP1684732A2 (en) * 2003-11-12 2006-08-02 Ranbaxy Laboratories Limited Ibuprofen-containing soft gelatin capsules
US8333989B2 (en) 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
CA2627351C (en) 2005-10-26 2012-05-01 Banner Pharmacaps, Inc. Lipophilic vehicle-based dual controlled release matrix system
US8895537B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating cardiovascular diseases
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
MX359366B (en) 2010-11-01 2018-09-26 Melinta Subsidiary Corp Pharmaceutical compositions.
IT1403660B1 (en) * 2011-01-28 2013-10-31 Abiogen Pharma Spa PHARMACEUTICAL COMPOSITION LIQUID CONTAINING PARACETAMOL
WO2012159962A1 (en) * 2011-05-20 2012-11-29 Aventis Pharma S.A. Pharmaceutical composition comprising ketoprofen
MX2015009105A (en) * 2013-01-14 2016-06-21 Infirst Healthcare Ltd Solid solution compositions and use in chronic inflammation.
RU2677346C2 (en) * 2013-01-14 2019-01-16 ИнФерст Хэлткэр Лимитед Compositions and methods for treating severe pain
KR20150129664A (en) * 2013-02-04 2015-11-20 인퍼스트 헬스케어 리미티드 Compositions and Methods for Treating Chronic Inflammatory and Inflammatory Diseases
CN109965089A (en) * 2019-05-14 2019-07-05 江苏欧克动物药业有限公司 A kind of emulsifiable natural oil coating agent applied to granular mixed feed
GB2595300B (en) * 2020-05-21 2024-03-27 Reckitt Benckiser Health Ltd Novel Formulation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011753A1 (en) * 1991-12-19 1993-06-24 R.P. Scherer Corporation Solvent system to be enclosed in capsules
WO1994014423A1 (en) * 1992-12-18 1994-07-07 R.P. Scherer Corporation Enhanced solubility pharmaceutical solutions
WO1994027611A1 (en) * 1993-05-26 1994-12-08 Doernhoefer Winfried Intramuscular and subcutaneous injection solution for animals
US5468502A (en) * 1994-12-20 1995-11-21 American Home Products Corporation Ibuprofen enhancing solvent system
WO1997026895A1 (en) * 1996-01-29 1997-07-31 Gene Komer Avermectin formulation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011753A1 (en) * 1991-12-19 1993-06-24 R.P. Scherer Corporation Solvent system to be enclosed in capsules
WO1994014423A1 (en) * 1992-12-18 1994-07-07 R.P. Scherer Corporation Enhanced solubility pharmaceutical solutions
WO1994027611A1 (en) * 1993-05-26 1994-12-08 Doernhoefer Winfried Intramuscular and subcutaneous injection solution for animals
US5468502A (en) * 1994-12-20 1995-11-21 American Home Products Corporation Ibuprofen enhancing solvent system
WO1997026895A1 (en) * 1996-01-29 1997-07-31 Gene Komer Avermectin formulation

Also Published As

Publication number Publication date
GB2331458A (en) 1999-05-26
GB2331458A9 (en)
GB9725420D0 (en) 1998-01-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20031121