BR112015012949A2 - composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit - Google Patents

composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit

Info

Publication number
BR112015012949A2
BR112015012949A2 BR112015012949A BR112015012949A BR112015012949A2 BR 112015012949 A2 BR112015012949 A2 BR 112015012949A2 BR 112015012949 A BR112015012949 A BR 112015012949A BR 112015012949 A BR112015012949 A BR 112015012949A BR 112015012949 A2 BR112015012949 A2 BR 112015012949A2
Authority
BR
Brazil
Prior art keywords
compound
kit
pharmaceutical composition
inhalation device
compounds
Prior art date
Application number
BR112015012949A
Other languages
English (en)
Inventor
Baker-Glenn Charles
Armani Elisabetta
Amari Gabriele
Riccaboni Mauro
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of BR112015012949A2 publication Critical patent/BR112015012949A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

resumo composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit a presente invenção se refere a novos compostos que são tanto inibidores da enzima fosfodiesterase-4 (pde4) quanto antagonistas de receptor muscarínico m3, aos métodos de preparação de tais compostos, a composições que os contêm e a seu uso terapêutico. 1/1
BR112015012949A 2012-12-05 2013-12-04 composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit BR112015012949A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12195726 2012-12-05
PCT/EP2013/075529 WO2014086855A1 (en) 2012-12-05 2013-12-04 Phenylethylpyridine derivatives as pde4-inhibitors

Publications (1)

Publication Number Publication Date
BR112015012949A2 true BR112015012949A2 (pt) 2017-07-11

Family

ID=47323965

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015012949A BR112015012949A2 (pt) 2012-12-05 2013-12-04 composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit

Country Status (10)

Country Link
US (1) US9169245B2 (pt)
EP (1) EP2928883B1 (pt)
KR (1) KR20150091061A (pt)
CN (1) CN104822671B (pt)
AR (1) AR093798A1 (pt)
BR (1) BR112015012949A2 (pt)
CA (1) CA2893622A1 (pt)
HK (1) HK1213245A1 (pt)
RU (1) RU2015121037A (pt)
WO (1) WO2014086855A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012266514A1 (en) * 2011-06-06 2014-01-09 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
AR098621A1 (es) 2013-12-05 2016-06-01 Chiesi Farm Spa Derivados de heteroarilo
RU2016121852A (ru) 2013-12-05 2017-12-07 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Производные бензгидрила для лечения респираторных заболеваний
US9763924B2 (en) 2014-06-05 2017-09-19 Chiesi Farmaceutici S.P.A. Aminoester derivatives
US9326976B2 (en) 2014-06-05 2016-05-03 Chiesi Farmaceutici S.P.A. Carbamate derivatives
WO2016177849A1 (en) 2015-05-07 2016-11-10 Chiesi Farmaceutici S.P.A. Aminoester derivatives
AR104822A1 (es) 2015-06-01 2017-08-16 Chiesi Farm Spa Derivado de aminoésteres
TW201710254A (zh) 2015-06-01 2017-03-16 吉斯藥品公司 胺基酯衍生物
US10857516B2 (en) 2017-03-16 2020-12-08 Waters Technologies Corporation Chromatographic compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008006509A1 (en) * 2006-07-14 2008-01-17 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors
EP2022783A1 (en) * 2007-08-08 2009-02-11 CHIESI FARMACEUTICI S.p.A. "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors"
EP2070913A1 (en) 2007-12-14 2009-06-17 CHIESI FARMACEUTICI S.p.A. Ester derivatives as phosphodiesterase inhibitors
EP2110375A1 (en) 2008-04-14 2009-10-21 CHIESI FARMACEUTICI S.p.A. Phosphodiesterase-4 inhibitors belonging to the tertiary amine class
EP2216327A1 (en) 2009-02-06 2010-08-11 CHIESI FARMACEUTICI S.p.A. Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors
AU2012266514A1 (en) 2011-06-06 2014-01-09 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
EP2760838B1 (en) 2011-09-26 2017-05-10 Chiesi Farmaceutici S.p.A. Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
RU2637945C2 (ru) 2012-06-04 2017-12-08 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Производные 1-фенил-2-пиридинил-алкиловых спиртов в качестве ингибиторов фосфодиэстеразы

Also Published As

Publication number Publication date
EP2928883B1 (en) 2018-02-14
EP2928883A1 (en) 2015-10-14
CN104822671A (zh) 2015-08-05
US9169245B2 (en) 2015-10-27
RU2015121037A (ru) 2017-01-11
CN104822671B (zh) 2017-10-31
US20140155373A1 (en) 2014-06-05
CA2893622A1 (en) 2014-06-12
AR093798A1 (es) 2015-06-24
WO2014086855A1 (en) 2014-06-12
KR20150091061A (ko) 2015-08-07
HK1213245A1 (zh) 2016-06-30

Similar Documents

Publication Publication Date Title
BR112015012949A2 (pt) composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit
EA201170772A1 (ru) Органические соединения
BR112015012720A2 (pt) derivados de feniletilpiridina como inibidores de pde4
PH12015501996A1 (en) Heterocyclic compounds and uses thereof
BR112013001088A2 (pt) "derivados substituídos como inibidores a quinase de imidazoquinolina"
BR112015012716A2 (pt) derivados de feniletilpiridina como inibidores de pde4
BR112016010080A8 (pt) compostos de pirazolopirimidina, composição farmacêutica e seu uso
EA201290183A1 (ru) Бензодиазепиновый ингибитор бромодомена
CR20140311A (es) Nuevos derivados de indolizina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen
NO20093009L (no) Kondensert ring heterocykel kinase modulatorer
EA201401351A1 (ru) Производные бензимидазол-пролина
EA201001205A1 (ru) Соединения, содержащие циклобутоксигруппу
SV2014004770A (es) Nuevos derivados de pirrol, su procedimiento de preparación y los composiciones farmacéuticas que los contienen
MX2011008864A (es) Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.
IN2014MN02598A (pt)
BR112014009006B8 (pt) Compostos heterocíclicos e métodos de uso dos mesmos
BR112013011448B8 (pt) Composto, composição farnmacêutica, e, uso do composto
EA201190017A1 (ru) Аминоэфирные производные алкалоидов и их медицинские композиции
EA201071224A1 (ru) Ингибиторы limk2, композиции, содержащие их, и способы их применения
EA201591830A1 (ru) Фармацевтические композиции, включающие эверолимус
BR112012009310B8 (pt) composto derivados de 2-oxo-1-pirrolidinil imidazotiadiazol, uso dos mesmos e composição farmacêutica compreendendo os mesmos
BR112015012825A2 (pt) piridopirazinas substituídas como inibidores de syk
GEP20186911B (en) Substituted chroman compounds as calcium sensing receptor modulators
BR112012014058A8 (pt) Derivados de 3,4,4a,10b- tetraidro-1h- tiopirano[4,3-c]isoquinolina
EA201600435A1 (ru) Кристаллическая форма (s)-(2-(6-хлор-7-метил-1н-бензо[d]имидазол-2-ил)-2-метилпирролидин-1-ил)(5-метокси-2-(2h-1,2,3-триазол-2-ил)фенил)метанона и ее применение в качестве антагонистов орексинового рецептора

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 5A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2494 DE 23-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.