BR112015010119A2 - composição farmacêutica que contém um inibidor de ace e um bloqueador do canal de cálcio - Google Patents
composição farmacêutica que contém um inibidor de ace e um bloqueador do canal de cálcioInfo
- Publication number
- BR112015010119A2 BR112015010119A2 BR112015010119A BR112015010119A BR112015010119A2 BR 112015010119 A2 BR112015010119 A2 BR 112015010119A2 BR 112015010119 A BR112015010119 A BR 112015010119A BR 112015010119 A BR112015010119 A BR 112015010119A BR 112015010119 A2 BR112015010119 A2 BR 112015010119A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- calcium channel
- channel blocker
- ace inhibitor
- composition containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1/1 resumo composição farmacêutica que contém um inibidor de ace e um bloqueador do canal de cálcio expõe-se uma composição farmacêutica sob a forma de uma mistura que consiste de a) um pó que contém um inibidor de ace, e b) um granulado que contém um bloqueador do canal de cálcio, em que o pó a) e o granulado b) contêm um ou mais excipientes. a composição é de utilidade no tratamento de condições relacionadas com hipertensão.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL401632A PL227900B1 (pl) | 2012-11-15 | 2012-11-15 | Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję |
PCT/IB2013/060069 WO2014076632A1 (en) | 2012-11-15 | 2013-11-12 | A pharmaceutical composition containing an ace inhibitor and a calcium channel blocker |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015010119A2 true BR112015010119A2 (pt) | 2017-07-11 |
Family
ID=49724636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015010119A BR112015010119A2 (pt) | 2012-11-15 | 2013-11-12 | composição farmacêutica que contém um inibidor de ace e um bloqueador do canal de cálcio |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP2919815B1 (pt) |
AU (1) | AU2013346397B2 (pt) |
BR (1) | BR112015010119A2 (pt) |
EA (1) | EA027568B1 (pt) |
ES (1) | ES2650468T3 (pt) |
HK (1) | HK1213807A1 (pt) |
HR (1) | HRP20171863T1 (pt) |
HU (1) | HUE035163T2 (pt) |
MX (1) | MX353689B (pt) |
MY (1) | MY170451A (pt) |
PH (1) | PH12015501036B1 (pt) |
PL (2) | PL227900B1 (pt) |
PT (1) | PT2919815T (pt) |
RS (1) | RS56664B1 (pt) |
SG (1) | SG11201503441XA (pt) |
UA (1) | UA114439C2 (pt) |
WO (1) | WO2014076632A1 (pt) |
ZA (1) | ZA201504265B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3275432A1 (en) * | 2016-07-25 | 2018-01-31 | H e x a l Aktiengesellschaft | Dosage form with ace inhibitor |
WO2021162562A2 (en) * | 2020-02-10 | 2021-08-19 | Adamed Pharma S.A. | Stable ramipril composition and fixed dose composition comprising thereof |
GB2595203A (en) * | 2020-03-03 | 2021-11-24 | Alkaloid Ad Skopje | Formulation |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743450A (en) | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
DE3739690A1 (de) | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
US5093129A (en) | 1989-01-30 | 1992-03-03 | E. R. Squibb & Sons, Inc. | Method for treating addiction to a drug of abuse employing an ace inhibitor |
BR0003282A (pt) | 2000-07-14 | 2002-02-26 | Libbs Farmaceutica Ltda | Associação farmacêutica para tratamento da hipertenção arterial e prevenção de doenças cardiovasculares outras, como infarto do miocárdio, acidente vascular cerebral e insuficiências cardìaca e renal |
CA2357982A1 (en) | 2001-09-28 | 2003-03-28 | Bernard Charles Sherman | Solid compositions comprising ramipril |
ATE357933T1 (de) | 2002-01-15 | 2007-04-15 | Actavis Group Hf | Formulierungen von quinapril und verwandte ace- hemmer |
US20030215526A1 (en) | 2002-03-08 | 2003-11-20 | Scott Stofik | Stable formulations of angiotensin converting enzyme (ACE) inhibitors |
US20050181055A1 (en) | 2003-10-08 | 2005-08-18 | Mathur Rajeev S. | Pharmaceutical compositions of quinapril |
EA011712B1 (ru) | 2004-03-29 | 2009-04-28 | Ле Лаборатуар Сервье | Способ производства твёрдой фармацевтической композиции |
HUP0401170A2 (en) * | 2004-06-10 | 2006-09-28 | Richter Gedeon Vegyeszet | Pharmaceutical composition comprising amlodipine besilate and lisinopril dihydrate and process for |
US10130624B2 (en) | 2005-03-15 | 2018-11-20 | Lupin Limited | Pharmaceutical compositions of amlodipine and benazepril |
AU2005336956A1 (en) * | 2005-09-28 | 2007-04-12 | Teva Pharmaceutical Industries Ltd. | Stable combinations of amlodipine besylate and benazepril hydrochloride |
EP1948136A1 (en) | 2005-11-07 | 2008-07-30 | King Pharmaceuticals Research and Development, Inc. | Compositions of stabilized ramipril in combination with another active agent |
WO2008065485A2 (en) | 2006-10-19 | 2008-06-05 | Torrent Pharmaceuticals Limited | Stable pharmaceutical compositions of a calcium channel blocker and an ace inhibitor |
CN102781430B (zh) | 2010-02-24 | 2015-09-09 | 赛诺菲-安万特德国有限公司 | 雷米普利和苯磺酸氨氯地平的固体药物制剂、及其制备 |
-
2012
- 2012-11-15 PL PL401632A patent/PL227900B1/pl unknown
-
2013
- 2013-11-12 EP EP13801824.7A patent/EP2919815B1/en active Active
- 2013-11-12 WO PCT/IB2013/060069 patent/WO2014076632A1/en active Application Filing
- 2013-11-12 ES ES13801824.7T patent/ES2650468T3/es active Active
- 2013-11-12 HU HUE13801824A patent/HUE035163T2/en unknown
- 2013-11-12 SG SG11201503441XA patent/SG11201503441XA/en unknown
- 2013-11-12 UA UAA201505719A patent/UA114439C2/uk unknown
- 2013-11-12 PT PT138018247T patent/PT2919815T/pt unknown
- 2013-11-12 MY MYPI2015001135A patent/MY170451A/en unknown
- 2013-11-12 EA EA201590529A patent/EA027568B1/ru unknown
- 2013-11-12 BR BR112015010119A patent/BR112015010119A2/pt active Search and Examination
- 2013-11-12 RS RS20171233A patent/RS56664B1/sr unknown
- 2013-11-12 PL PL13801824T patent/PL2919815T3/pl unknown
- 2013-11-12 MX MX2015006122A patent/MX353689B/es active IP Right Grant
- 2013-11-12 AU AU2013346397A patent/AU2013346397B2/en not_active Ceased
-
2015
- 2015-05-08 PH PH12015501036A patent/PH12015501036B1/en unknown
- 2015-06-12 ZA ZA2015/04265A patent/ZA201504265B/en unknown
-
2016
- 2016-02-19 HK HK16101893.8A patent/HK1213807A1/zh not_active IP Right Cessation
-
2017
- 2017-11-29 HR HRP20171863TT patent/HRP20171863T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
PL227900B1 (pl) | 2018-01-31 |
EA027568B1 (ru) | 2017-08-31 |
UA114439C2 (uk) | 2017-06-12 |
AU2013346397A1 (en) | 2015-06-18 |
ES2650468T3 (es) | 2018-01-18 |
ZA201504265B (en) | 2017-11-29 |
HUE035163T2 (en) | 2018-05-02 |
PT2919815T (pt) | 2017-12-11 |
HK1213807A1 (zh) | 2016-07-15 |
EP2919815A1 (en) | 2015-09-23 |
RS56664B1 (sr) | 2018-03-30 |
EA201590529A1 (ru) | 2015-09-30 |
WO2014076632A1 (en) | 2014-05-22 |
MX353689B (es) | 2018-01-23 |
PL2919815T3 (pl) | 2018-01-31 |
PH12015501036A1 (en) | 2015-08-17 |
PL401632A1 (pl) | 2014-05-26 |
MY170451A (en) | 2019-07-31 |
AU2013346397B2 (en) | 2017-09-14 |
SG11201503441XA (en) | 2015-05-28 |
PH12015501036B1 (en) | 2015-08-17 |
EP2919815B1 (en) | 2017-09-06 |
MX2015006122A (es) | 2015-08-05 |
HRP20171863T1 (hr) | 2018-01-12 |
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Legal Events
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2493 DE 16/10/2018. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |