BR112015008725A2 - método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduo - Google Patents
método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduoInfo
- Publication number
- BR112015008725A2 BR112015008725A2 BR112015008725A BR112015008725A BR112015008725A2 BR 112015008725 A2 BR112015008725 A2 BR 112015008725A2 BR 112015008725 A BR112015008725 A BR 112015008725A BR 112015008725 A BR112015008725 A BR 112015008725A BR 112015008725 A2 BR112015008725 A2 BR 112015008725A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- absence
- determining
- bacterial infection
- infection
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
- G01N33/0055—Radionuclides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1206—Administration of radioactive gases, aerosols or breath tests
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- Combustion & Propulsion (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Dispersion Chemistry (AREA)
Abstract
resumo “método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduo” a invenção é dirigida aos métodos de detecção de infecção pulmonar, trato gastrointestinal, e infecção sistêmica através da medida de proporções isotópica de 13co2/12co2 de dióxido de carbono gasoso em amostras de exalado pulmonar de um indivíduo após a administração de um composto marcado isotopicamente-13c. 1/1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261715992P | 2012-10-19 | 2012-10-19 | |
PCT/US2013/063365 WO2014062392A1 (en) | 2012-10-19 | 2013-10-04 | Methods for detecting bacterial infections |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015008725A2 true BR112015008725A2 (pt) | 2017-07-04 |
Family
ID=49447823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015008725A BR112015008725A2 (pt) | 2012-10-19 | 2013-10-04 | método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduo |
Country Status (7)
Country | Link |
---|---|
US (1) | US9518972B2 (pt) |
EP (1) | EP2909329B1 (pt) |
JP (1) | JP6364665B2 (pt) |
CN (1) | CN104822841B (pt) |
BR (1) | BR112015008725A2 (pt) |
RU (1) | RU2015118586A (pt) |
WO (1) | WO2014062392A1 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014058848A2 (en) | 2012-10-10 | 2014-04-17 | Stc.Unm | Methods for diagnosing bacterial infections |
BR112015008725A2 (pt) | 2012-10-19 | 2017-07-04 | Avisa Pharma Inc | método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduo |
RU2015128043A (ru) * | 2012-12-12 | 2017-01-19 | Ависа Фарма Инк. | Определение местоположения бактериальной нагрузки в легких |
EP3106859B1 (en) * | 2014-02-12 | 2019-12-04 | Sekisui Medical Co., Ltd. | Carbon isotope analysis device and carbon isotope analysis method |
US10226484B2 (en) | 2014-12-01 | 2019-03-12 | Peter Y Novak | Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof |
JP6471983B2 (ja) * | 2015-06-16 | 2019-02-20 | 日本電信電話株式会社 | 呼気試料中イソプレンの天然の安定炭素同位体比(13c/12c)を分析する方法、および血糖値のモニタリング方法 |
JP6446657B2 (ja) * | 2015-06-16 | 2019-01-09 | 日本電信電話株式会社 | 脂質の代謝をモニタリングする方法 |
WO2017123582A1 (en) | 2016-01-11 | 2017-07-20 | Avisa Pharma Inc. | Methods for detecting bacterial lung infections |
FI127556B (en) * | 2017-02-06 | 2018-09-14 | Teknologian Tutkimuskeskus Vtt Oy | Respiratory analysis method and apparatus |
US10183041B2 (en) | 2017-04-12 | 2019-01-22 | Vector Vitale Ip Llc | Antibacterial composition and its use in treating bacterial infections |
US10330592B2 (en) | 2017-07-21 | 2019-06-25 | Serguei Koulikov | Laser absorption spectroscopy isotopic gas analyzer |
US11025028B2 (en) * | 2017-08-24 | 2021-06-01 | National University Corporation Nagoya University | Light generating device, and carbon isotope analyzing device and carbon isotope analyzing method employing same |
CN108489925A (zh) * | 2018-04-05 | 2018-09-04 | 范宪华 | 一种用呼吸检测胃肠道恶性致病细菌的仪器 |
US11035789B2 (en) * | 2019-04-03 | 2021-06-15 | Picomole Inc. | Cavity ring-down spectroscopy system and method of modulating a light beam therein |
KR102551168B1 (ko) * | 2020-05-06 | 2023-07-04 | 한국원자력연구원 | 결핵균을 검출하는 방법 |
CN113189316A (zh) * | 2021-04-14 | 2021-07-30 | 必睿思(杭州)科技有限公司 | 一种呼出气及呼出气冷凝液中水同位素示踪剂的检测方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2844503B2 (ja) * | 1991-11-20 | 1999-01-06 | 東京瓦斯株式会社 | ガス測定装置 |
US5317156A (en) | 1992-01-29 | 1994-05-31 | Sri International | Diagnostic tests using near-infrared laser absorption spectroscopy |
JP3274605B2 (ja) | 1996-05-01 | 2002-04-15 | 日本無線株式会社 | 炭素同位体分析装置 |
US5957858A (en) | 1996-07-26 | 1999-09-28 | Polestar Technologies, Inc. | Systems and methods for monitoring relative concentrations of different isotopic forms of a chemical species |
JP3336261B2 (ja) * | 1998-07-17 | 2002-10-21 | 日本酸素株式会社 | 半導体レーザを用いた同位体の分光分析方法 |
US6486474B1 (en) | 1999-08-13 | 2002-11-26 | Regents Of The University Of Minnesota | Infrared spectrometer for the measurement of isotopic ratios |
US6800855B1 (en) | 1999-12-27 | 2004-10-05 | Nippon Sanso Corporation | Spectroscopic method for analyzing isotopes by using a semiconductor laser |
JP2002350303A (ja) * | 2001-05-29 | 2002-12-04 | Aloka Co Ltd | 呼気ガス容器セット |
GB0120027D0 (en) * | 2001-08-16 | 2001-10-10 | Isis Innovation | Spectroscopic breath analysis |
US6778269B2 (en) | 2001-09-04 | 2004-08-17 | Board Of Regents, The University Of Texas System | Detecting isotopes and determining isotope ratios using raman spectroscopy |
WO2008057662A2 (en) | 2006-10-28 | 2008-05-15 | Yu Jiangchen | Wavelength modulation spectroscopy for simultaneous measurement of two or more gas ingredients |
WO2008134026A1 (en) * | 2007-04-25 | 2008-11-06 | Stc.Unm | Analysis of p. aeruginosa infection in patients |
JP2011512532A (ja) * | 2008-02-15 | 2011-04-21 | ザ サイエンス アンド テクノロジー ファシリティーズ カウンシル | 赤外分光計 |
WO2012162695A2 (en) * | 2011-05-26 | 2012-11-29 | Southwest Sciences Incorporated | Laser based, temperature insensitive, carbon dioxide isotope ratio measurement |
BR112015008725A2 (pt) | 2012-10-19 | 2017-07-04 | Avisa Pharma Inc | método para determinar a presença ou ausência de uma infecção bacteriana em um indivíduo |
RU2015128043A (ru) * | 2012-12-12 | 2017-01-19 | Ависа Фарма Инк. | Определение местоположения бактериальной нагрузки в легких |
-
2013
- 2013-10-04 BR BR112015008725A patent/BR112015008725A2/pt not_active IP Right Cessation
- 2013-10-04 EP EP13779680.1A patent/EP2909329B1/en not_active Not-in-force
- 2013-10-04 WO PCT/US2013/063365 patent/WO2014062392A1/en active Application Filing
- 2013-10-04 JP JP2015537719A patent/JP6364665B2/ja not_active Expired - Fee Related
- 2013-10-04 US US14/045,856 patent/US9518972B2/en active Active
- 2013-10-04 CN CN201380054746.4A patent/CN104822841B/zh not_active Expired - Fee Related
- 2013-10-04 RU RU2015118586A patent/RU2015118586A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2014062392A1 (en) | 2014-04-24 |
US9518972B2 (en) | 2016-12-13 |
CN104822841B (zh) | 2018-04-20 |
EP2909329A1 (en) | 2015-08-26 |
JP6364665B2 (ja) | 2018-08-01 |
JP2015536449A (ja) | 2015-12-21 |
US20140114206A1 (en) | 2014-04-24 |
CN104822841A (zh) | 2015-08-05 |
EP2909329B1 (en) | 2017-04-12 |
RU2015118586A (ru) | 2016-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law | ||
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |