BR112014023603A8 - METHOD FOR BUTANOL PRODUCTION AND COMPOSITION - Google Patents

METHOD FOR BUTANOL PRODUCTION AND COMPOSITION

Info

Publication number
BR112014023603A8
BR112014023603A8 BR112014023603A BR112014023603A BR112014023603A8 BR 112014023603 A8 BR112014023603 A8 BR 112014023603A8 BR 112014023603 A BR112014023603 A BR 112014023603A BR 112014023603 A BR112014023603 A BR 112014023603A BR 112014023603 A8 BR112014023603 A8 BR 112014023603A8
Authority
BR
Brazil
Prior art keywords
composition
production
acetate
butanol production
relates
Prior art date
Application number
BR112014023603A
Other languages
Portuguese (pt)
Other versions
BR112014023603A2 (en
Inventor
Ann Maggio-Hall Lori
Original Assignee
Butamax Advanced Biofuels Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Butamax Advanced Biofuels Llc filed Critical Butamax Advanced Biofuels Llc
Publication of BR112014023603A2 publication Critical patent/BR112014023603A2/pt
Publication of BR112014023603A8 publication Critical patent/BR112014023603A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01008—Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01005—Aldehyde dehydrogenase [NAD(P)+] (1.2.1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01001—Pyruvate decarboxylase (4.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01009—Dihydroxy-acid dehydratase (4.2.1.9), i.e. acetohydroxyacid dehydratase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

MÉTODO PARA PRODUÇÃO DE BUTANOL E COMPOSIÇÃO A invenção refere-se aos campos da microbiologia industrial e produção de álcool. Mais especificamente, a invenção refere-se a uma produção aumentada de isômeros do butano! por microrganismos recombinantes contendo uma via do butano! elaborada geneticamente e atividades de ruptura dos genes em nas vias para produção de subprodutos durante a fermentação quando os microrganismos são cultivados em um meio de fermentação contendo acetato. Nas realizações, microrganismos recombinantes têm uma taxa de crescimento aumentada em um meio de fermentação contendo acetato como um suplemento de C2.METHOD FOR BUTANOL PRODUCTION AND COMPOSITION The invention relates to the fields of industrial microbiology and alcohol production. More specifically, the invention relates to an increased production of butane isomers! by recombinant microorganisms containing a butane pathway! genetically engineered and gene-disrupting activities in pathways for producing by-products during fermentation when microorganisms are cultured in an acetate-containing fermentation medium. In embodiments, recombinant microorganisms have an increased growth rate in a fermentation medium containing acetate as a C2 supplement.

BR112014023603A 2012-03-23 2013-03-15 METHOD FOR BUTANOL PRODUCTION AND COMPOSITION BR112014023603A8 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261615174P 2012-03-23 2012-03-23
PCT/US2013/032159 WO2013142338A1 (en) 2012-03-23 2013-03-15 Acetate supplemention of medium for butanologens

Publications (2)

Publication Number Publication Date
BR112014023603A2 BR112014023603A2 (en) 2017-06-20
BR112014023603A8 true BR112014023603A8 (en) 2017-07-25

Family

ID=48014374

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014023603A BR112014023603A8 (en) 2012-03-23 2013-03-15 METHOD FOR BUTANOL PRODUCTION AND COMPOSITION

Country Status (10)

Country Link
US (1) US9689004B2 (en)
EP (1) EP2828391A1 (en)
JP (1) JP2015510774A (en)
KR (1) KR20140146616A (en)
CN (1) CN104284981A (en)
AU (1) AU2013235391A1 (en)
BR (1) BR112014023603A8 (en)
CA (1) CA2868153A1 (en)
MX (1) MX2014011355A (en)
WO (1) WO2013142338A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
EP2337856A1 (en) 2008-09-29 2011-06-29 Butamax Advanced Biofuels Llc INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
EP2519628A2 (en) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
AU2011218090B2 (en) 2010-02-17 2016-06-23 Butamax(Tm) Advanced Biofuels Llc Improving activity of Fe-S cluster requiring proteins
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
EP3269806B1 (en) 2010-09-07 2020-05-27 Butamax (TM) Advanced Biofuels LLC Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
JP6093764B2 (en) 2011-07-28 2017-03-08 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー Ketoisovalerate decarboxylase enzyme and method of use thereof
EP2798072A2 (en) 2011-12-30 2014-11-05 Butamax Advanced Biofuels LLC Fermentative production of alcohols
CA2873109A1 (en) 2012-05-11 2013-11-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
US9593349B2 (en) 2012-08-22 2017-03-14 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US9840724B2 (en) 2012-09-21 2017-12-12 Butamax Advanced Biofuels Llc Production of renewable hydrocarbon compositions
WO2014052670A1 (en) 2012-09-26 2014-04-03 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
WO2014106107A2 (en) * 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
HUE045200T2 (en) 2013-03-14 2019-12-30 Du Pont Glycerol 3- phosphate dehydrogenase for butanol production
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening
CA2957920A1 (en) 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same
KR101589703B1 (en) * 2015-10-15 2016-01-28 (주)서전기전 Electricity rate saving type switchgear system using an emergency generator
US11913046B2 (en) 2018-04-23 2024-02-27 Inbiose N.V. Increasing export of 2'fucosyllactose from microbial cells through the expression of a heterologous nucleic acid
EP3784772A1 (en) 2018-04-23 2021-03-03 DuPont Nutrition Biosciences ApS Increasing activity of 2' fucosyllactose transporters endogenous to microbial cells

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1869197A2 (en) 2005-04-12 2007-12-26 E.I. Dupont De Nemours And Company Treatment of biomass to obtain ethanol
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
US20080274526A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
EP1948814B1 (en) 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US7659104B2 (en) 2006-05-05 2010-02-09 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US7541173B2 (en) 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US20080293086A1 (en) * 2006-09-18 2008-11-27 Cobalt Technologies, Inc. A Delaware Corporation Real time monitoring of microbial enzymatic pathways
EP2097528A2 (en) 2006-10-31 2009-09-09 DSMIP Assets B.V. Butanol production in a eukaryotic cell
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
US8426173B2 (en) 2007-05-02 2013-04-23 Butamax (Tm) Advanced Biofuels Llc Method for the production of 1-butanol
EP2222841B1 (en) 2007-12-20 2015-08-26 Butamax (TM) Advanced Biofuels LLC Ketol-acid reductoisomerase using nadh
US8372612B2 (en) 2007-12-21 2013-02-12 Butamax(Tm) Advanced Biofuels Llc Production of four carbon alcohols using improved strain
US8518678B2 (en) 2007-12-21 2013-08-27 Butamax(Tm) Advanced Biofuels Llc Strain comprising increased expression of a CFA coding region for butanol production
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
US8389252B2 (en) 2008-05-12 2013-03-05 Butamax(Tm) Advanced Biofuels Llc Yeast strain for production of four carbon alcohols
WO2009143455A2 (en) 2008-05-22 2009-11-26 Microbia, Inc. Engineering resistance to aliphatic alcohols
US8828695B2 (en) 2008-06-04 2014-09-09 Butamax Advanced Biofuels Llc Method for producing butanol using two-phase extractive fermentation
WO2009149270A2 (en) 2008-06-04 2009-12-10 E. I. Du Pont De Nemours And Company A method for producing butanol using two-phase extractive fermentation
ES2521675T3 (en) 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identification and use of [2Fe-2S] -dihydroxy acid-bacterial dehydratases
US8637281B2 (en) 2008-09-29 2014-01-28 Butamax(Tm) Advanced Biofuels Llc Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria
AU2009296227A1 (en) 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
EP2337856A1 (en) 2008-09-29 2011-06-29 Butamax Advanced Biofuels Llc INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
WO2010037119A1 (en) 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria
EP2350298A1 (en) 2008-10-27 2011-08-03 ButamaxTM Advanced Biofuels LLC Carbon pathway optimized production hosts for the production of isobutanol
US8465964B2 (en) 2008-11-13 2013-06-18 Butamax (TM) Advanced Biofules LLC Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
US8828694B2 (en) 2008-11-13 2014-09-09 Butamax Advanced Biofuels Llc Production of isobutanol in yeast mitochondria
US8652823B2 (en) 2008-12-03 2014-02-18 Butamax(Tm) Advanced Biofuels Llc Strain for butanol production with increased membrane unsaturated trans fatty acids
US8795992B2 (en) 2008-12-29 2014-08-05 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving cell wall integrity pathway
US8455225B2 (en) 2008-12-29 2013-06-04 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway
US8557562B2 (en) 2008-12-29 2013-10-15 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving filamentous growth response
US8614085B2 (en) 2009-02-27 2013-12-24 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving a multidrug efflux pump gene
US20120058541A1 (en) 2009-05-22 2012-03-08 Butamax(Tm) Advanced Biofuels Llc Engineering resistance to aliphatic alcohols
WO2010151525A1 (en) 2009-06-22 2010-12-29 Gevo, Inc. Yeast organisms for the production of isobutanol
BR112012006939A2 (en) 2009-09-29 2015-09-08 Butamax Tm Advanced Biofuels Recombinant yeast production host cell and method for producing a product selected from the group consisting of 2,3-butanediol, isobutanol, 2-butanol, 1-butanol, 2-butanone, valine, leucine, lactic acid, malic acid , alcohol, isoampyl and isoprenoids
IN2012DN02396A (en) 2009-09-29 2015-08-21 Butamax Tm Advanced Biofuels
BR112012007168A2 (en) 2009-09-29 2019-09-24 Butamax Advanced Biofuels Llc "yeast cell, isobutanol producing microbial cell, microbial host cell, method for conversion of acetolate to dihydroxyisovalerate, method for the production of isobutanol and plasmid"
US20110195505A1 (en) 2009-10-08 2011-08-11 Butamax(Tm) Advanced Biofuels Llc Bacterial strains for butanol production
KR20120115500A (en) 2009-11-23 2012-10-18 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 Method for producing butanol using extractive fermentation with electrolyte addition
NZ599415A (en) 2009-11-23 2014-06-27 Butamax Tm Advanced Biofuels Method for producing butanol using extractive fermentation with osmolyte addition
GB2487889B (en) * 2009-11-24 2012-12-19 Gevo Inc Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
EP2519628A2 (en) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
BR112012016043A2 (en) 2009-12-29 2015-11-24 Butamax Advanced Biofuels Llc "Recombinant yeast host cell, methods for reproducing isobutanol, for increasing glucose consumption, for enhancing the formation of a biosynthetic pathway product and for improving redox balance"
CA2789583C (en) * 2010-02-12 2017-01-17 Gevo, Inc. Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
AU2011218090B2 (en) 2010-02-17 2016-06-23 Butamax(Tm) Advanced Biofuels Llc Improving activity of Fe-S cluster requiring proteins
WO2011159894A1 (en) 2010-06-17 2011-12-22 Butamax(Tm) Advanced Biofuels Llc Yeast production culture for the production of butanol
US8697404B2 (en) 2010-06-18 2014-04-15 Butamax Advanced Biofuels Llc Enzymatic production of alcohol esters for recovery of diols produced by fermentation
US9040263B2 (en) 2010-07-28 2015-05-26 Butamax Advanced Biofuels Llc Production of alcohol esters and in situ product removal during alcohol fermentation
US9206448B2 (en) 2010-06-18 2015-12-08 Butamax Advanced Biofuels Llc Extraction solvents derived from oil for alcohol removal in extractive fermentation
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
US9012190B2 (en) 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
EP3269806B1 (en) 2010-09-07 2020-05-27 Butamax (TM) Advanced Biofuels LLC Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
US20120258873A1 (en) 2011-04-06 2012-10-11 Butamax(Tm) Advanced Biofuels Llc Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production
US20130035515A1 (en) 2011-06-17 2013-02-07 Butamax(Tm) Advanced Biofuels Llc Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation
JP6093764B2 (en) 2011-07-28 2017-03-08 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー Ketoisovalerate decarboxylase enzyme and method of use thereof
AU2012362144A1 (en) 2011-12-30 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Genetic switches for butanol production
EP2798072A2 (en) 2011-12-30 2014-11-05 Butamax Advanced Biofuels LLC Fermentative production of alcohols
CA2873109A1 (en) 2012-05-11 2013-11-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
US9109196B2 (en) 2012-09-12 2015-08-18 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
WO2014052670A1 (en) 2012-09-26 2014-04-03 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
EP2900825A1 (en) 2012-09-28 2015-08-05 Butamax Advanced Biofuels LLC Production of fermentation products
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
US20140186911A1 (en) 2012-12-28 2014-07-03 Butamax Advanced Biofuels Llc Recombinant host cells and methods for producing butanol
HUE045200T2 (en) 2013-03-14 2019-12-30 Du Pont Glycerol 3- phosphate dehydrogenase for butanol production
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening

Also Published As

Publication number Publication date
BR112014023603A2 (en) 2017-06-20
CA2868153A1 (en) 2013-09-26
CN104284981A (en) 2015-01-14
WO2013142338A1 (en) 2013-09-26
MX2014011355A (en) 2014-12-05
EP2828391A1 (en) 2015-01-28
JP2015510774A (en) 2015-04-13
KR20140146616A (en) 2014-12-26
AU2013235391A1 (en) 2014-09-04
US9689004B2 (en) 2017-06-27
US20130252296A1 (en) 2013-09-26

Similar Documents

Publication Publication Date Title
BR112014023603A8 (en) METHOD FOR BUTANOL PRODUCTION AND COMPOSITION
MX2019004568A (en) Improved production of fatty acid derivatives.
BR112014026206A2 (en) cellular systems and methods for improving fatty acid synthesis through the expression of dehydrogenase
BR112015010134A2 (en) PROCESS FOR CONSUMPTION OF ACETATE DURING THE ETHANOL FERMENTATION OF CELLULOSIC RAW MATERIALS
WO2013006479A3 (en) Mammalian cell culture
EP4269584A3 (en) Selective antisense compounds and uses thereof
IN2015DN01606A (en)
MX347843B (en) A microorganism for methionine production with enhanced glucose import.
MX2015007361A (en) Acp-mediated production of fatty acid derivatives.
MX2022002057A (en) Enzyme variants with improved ester synthase properties.
SG10201805087VA (en) Artificial match-type mirna for controlling gene expression and use therefor
MY182946A (en) Production of organic acids by fermentation at low ph
SG10201809452RA (en) Cell culture compositions with antioxidants and methods for polypeptide production
MX2020001357A (en) Microbial production of fatty amines.
EA201491785A1 (en) METHOD OF ENZYMATION
BR112015030105A2 (en) CONSTRUCTION OF A CHIMERIC GENE, RECOMBINANT VECTOR, THEIR USES, AS WELL AS A METHOD FOR THE PRODUCTION OF A MONOCOTYLEDONOUS PLANT WITH HIGHER YIELD COMPARED TO A MONOCOTYLEDONOUS PLANT OF THE CORRESPONDING WILD TYPE
GB201009882D0 (en) Yeast strains modified in their sophorolipid production and uses thereof
BR112016005456A2 (en) A manufacturing method of L-amino acid from the seaweed origin biomass
WO2012151071A3 (en) Regulatory sequences to control gene expression in plants
WO2014049382A3 (en) Ethylenediamine fermentative production by a recombinant microorganism
EP4282972A3 (en) Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
WO2015103001A8 (en) Expression of a hap transcriptional complex subunit
WO2014100742A3 (en) Modulation of expression of acyltransferases to modify hydroxycinnamic acid content
MX2014007760A (en) Bacteria with reconstructed transcriptional units and the uses thereof.
WO2012129449A3 (en) High level production of recombinant proteins

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]