BR112014016971A2 - pirimidinas e triazinas fundidas substituídas e seus usos - Google Patents
pirimidinas e triazinas fundidas substituídas e seus usosInfo
- Publication number
- BR112014016971A2 BR112014016971A2 BR112014016971A BR112014016971A BR112014016971A2 BR 112014016971 A2 BR112014016971 A2 BR 112014016971A2 BR 112014016971 A BR112014016971 A BR 112014016971A BR 112014016971 A BR112014016971 A BR 112014016971A BR 112014016971 A2 BR112014016971 A2 BR 112014016971A2
- Authority
- BR
- Brazil
- Prior art keywords
- triazines
- substituted fused
- prophylaxis
- treatment
- fused pyrimidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
resumo da patente de invenção para: pirimidinas e triazinas fundidas substituídas e seus usos o presente pedido se refere a novas pirimidinas e triazinas fundidas substituídas, aos processos para a sua preparação, ao seu uso por si só ou em combinações para o tratamento e/ou profilaxia de doenças, e à sua utilização para a produção de medicamentos para o tratamento e/ou profilaxia de doenças, em particular para o tratamento e/ou profilaxia de distúrbios cardiovasculares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012200349A DE102012200349A1 (de) | 2012-01-11 | 2012-01-11 | Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung |
PCT/EP2013/050381 WO2013104703A1 (de) | 2012-01-11 | 2013-01-10 | Substituierte annellierte pyrimidine und triazine und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014016971A2 true BR112014016971A2 (pt) | 2017-06-13 |
BR112014016971A8 BR112014016971A8 (pt) | 2017-07-04 |
Family
ID=47559479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014016971A BR112014016971A8 (pt) | 2012-01-11 | 2013-01-10 | pirimidinas e triazinas fundidas substituídas e seus usos |
Country Status (29)
Country | Link |
---|---|
US (2) | US20140357637A1 (pt) |
EP (1) | EP2802592A1 (pt) |
JP (1) | JP6251183B2 (pt) |
KR (1) | KR20140114416A (pt) |
CN (1) | CN104812762B (pt) |
AP (1) | AP2014007844A0 (pt) |
AU (1) | AU2013208968A1 (pt) |
BR (1) | BR112014016971A8 (pt) |
CA (1) | CA2860855A1 (pt) |
CL (1) | CL2014001779A1 (pt) |
CO (1) | CO7000776A2 (pt) |
CR (1) | CR20140327A (pt) |
CU (1) | CU20140082A7 (pt) |
DE (1) | DE102012200349A1 (pt) |
DO (1) | DOP2014000160A (pt) |
EA (1) | EA025837B1 (pt) |
EC (1) | ECSP14008556A (pt) |
GT (1) | GT201400147A (pt) |
HK (1) | HK1211585A1 (pt) |
IL (1) | IL233460A0 (pt) |
MA (1) | MA35844B1 (pt) |
MX (1) | MX2014008201A (pt) |
NZ (1) | NZ626394A (pt) |
PE (1) | PE20142293A1 (pt) |
PH (1) | PH12014501595A1 (pt) |
SG (2) | SG10201605655UA (pt) |
TN (1) | TN2014000298A1 (pt) |
WO (1) | WO2013104703A1 (pt) |
ZA (1) | ZA201405042B (pt) |
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DE102012200349A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung |
DE102012200360A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Triazine und ihre Verwendung |
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WO2017013010A1 (de) | 2015-07-23 | 2017-01-26 | Bayer Pharma Aktiengesellschaft | Stimulatoren und/oder aktivatoren der löslichen guanylatzyklase (sgc) in kombination mit einem inhibitor der neutralen endopeptidase (nep inhibitor) und/oder einem angiotensin aii-antagonisten und ihre verwendung |
KR101753652B1 (ko) * | 2015-10-21 | 2017-07-05 | 한국화학연구원 | N-아릴-1h-피라졸로피리딘-3-아민 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 melk 관련 질환의 예방 또는 치료용 약학적 조성물 |
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CA2866213A1 (en) | 2012-03-06 | 2013-09-12 | Bayer Intellectual Property Gmbh | Substituted azabicycles and use thereof |
AU2014222739A1 (en) | 2013-03-01 | 2015-09-03 | Bayer Pharma Aktiengesellschaft | Trifluormethyl-substituted ring-fused pyrimidines and use thereof |
WO2014131741A1 (de) | 2013-03-01 | 2014-09-04 | Bayer Pharma Aktiengesellschaft | Benzyl-substituierte pyrazolopyridine und ihre verwendung |
WO2015004105A1 (de) | 2013-07-10 | 2015-01-15 | Bayer Pharma Aktiengesellschaft | Benzyl-1h-pyrazolo[3,4-b]pyridine und ihre verwendung |
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2012
- 2012-01-11 DE DE102012200349A patent/DE102012200349A1/de not_active Withdrawn
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2013
- 2013-01-10 SG SG10201605655UA patent/SG10201605655UA/en unknown
- 2013-01-10 CA CA2860855A patent/CA2860855A1/en not_active Abandoned
- 2013-01-10 US US14/371,046 patent/US20140357637A1/en not_active Abandoned
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- 2013-01-10 AU AU2013208968A patent/AU2013208968A1/en not_active Abandoned
- 2013-01-10 EP EP13700288.7A patent/EP2802592A1/de not_active Withdrawn
- 2013-01-10 MX MX2014008201A patent/MX2014008201A/es not_active Application Discontinuation
- 2013-01-10 KR KR1020147021969A patent/KR20140114416A/ko not_active Application Discontinuation
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- 2013-01-10 CN CN201380013679.1A patent/CN104812762B/zh not_active Expired - Fee Related
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- 2014-07-09 EC ECIEPI20148556A patent/ECSP14008556A/es unknown
- 2014-07-09 TN TNP2014000298A patent/TN2014000298A1/fr unknown
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- 2014-07-10 PH PH12014501595A patent/PH12014501595A1/en unknown
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2015
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