BR112014016389A8 - composições e uso das mesmas para o tratamento de distúrbios e doenças hepáticas - Google Patents
composições e uso das mesmas para o tratamento de distúrbios e doenças hepáticasInfo
- Publication number
- BR112014016389A8 BR112014016389A8 BR112014016389A BR112014016389A BR112014016389A8 BR 112014016389 A8 BR112014016389 A8 BR 112014016389A8 BR 112014016389 A BR112014016389 A BR 112014016389A BR 112014016389 A BR112014016389 A BR 112014016389A BR 112014016389 A8 BR112014016389 A8 BR 112014016389A8
- Authority
- BR
- Brazil
- Prior art keywords
- diseases
- compositions
- treatment
- liver disorders
- disorders
- Prior art date
Links
- 208000019423 liver disease Diseases 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21043—Classical-complement-pathway C3/C5 convertase (3.4.21.43)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biotechnology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261586975P | 2012-01-16 | 2012-01-16 | |
PCT/US2013/021752 WO2013109635A1 (en) | 2012-01-16 | 2013-01-16 | Compositions and methods for the treatment of hepatic diseases and disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014016389A2 BR112014016389A2 (pt) | 2017-06-13 |
BR112014016389A8 true BR112014016389A8 (pt) | 2021-06-08 |
Family
ID=48799623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014016389A BR112014016389A8 (pt) | 2012-01-16 | 2013-01-16 | composições e uso das mesmas para o tratamento de distúrbios e doenças hepáticas |
Country Status (19)
Country | Link |
---|---|
US (4) | US9713630B2 (pt) |
EP (1) | EP2804613A4 (pt) |
JP (1) | JP6632802B2 (pt) |
KR (3) | KR20220042485A (pt) |
CN (2) | CN113813294A (pt) |
AP (1) | AP2014007804A0 (pt) |
AU (2) | AU2013209887B2 (pt) |
BR (1) | BR112014016389A8 (pt) |
CA (2) | CA3208225A1 (pt) |
CR (1) | CR20140342A (pt) |
EA (1) | EA201491081A1 (pt) |
HK (1) | HK1198909A1 (pt) |
IL (1) | IL233639B (pt) |
NI (1) | NI201400076A (pt) |
NZ (1) | NZ625592A (pt) |
PE (1) | PE20142295A1 (pt) |
PH (1) | PH12014501620A1 (pt) |
SG (3) | SG10202013014RA (pt) |
WO (1) | WO2013109635A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2804613A4 (en) | 2012-01-16 | 2015-12-09 | Elizabeth Mckenna | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND HEPATIC DISORDERS |
US20140086849A1 (en) | 2012-09-21 | 2014-03-27 | Elizabeth McKenna | Naturally-Occurring CpG Oligonucleotide Compositions and Therapeutic Applications Thereof |
US20170232047A1 (en) * | 2012-01-16 | 2017-08-17 | Elizabeth McKenna | Control of Cellular Redox Levels |
EP3033091B1 (en) * | 2013-08-16 | 2022-09-07 | Versitech Limited | Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma |
KR20170128247A (ko) * | 2015-01-23 | 2017-11-22 | 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 암 예방에서 단쇄 지방산의 용도 |
KR20170032815A (ko) | 2015-09-15 | 2017-03-23 | 경희대학교 산학협력단 | 신규 유산균 및 퇴행성 뇌질환 또는 인지기능의 예방, 개선 또는 치료용 조성물 |
EA201891142A1 (ru) * | 2015-11-10 | 2018-11-30 | Элизабет Маккенна | Контроль клеточных окислительно-восстановительных уровней |
US20170143972A1 (en) * | 2015-11-19 | 2017-05-25 | Boston Scientific Neuromodulation Corporation | Neuromodulation for neuroinflammation treatments with parameters controlled using biomarkers |
CN107080755A (zh) * | 2017-04-28 | 2017-08-22 | 青岛东海药业有限公司 | 凝结芽孢杆菌在制备预防或治疗慢性阻塞性肺疾病制剂中的应用 |
KR102265538B1 (ko) * | 2018-02-02 | 2021-06-16 | 주식회사 고바이오랩 | 락토바실러스 플란타럼 kbl396 균주 및 그 용도 |
RU2696773C1 (ru) * | 2018-08-13 | 2019-08-06 | Алексей Николаевич Осинцев | Способ получения лекарственного препарата пептидной природы с контролируемым и последовательным высвобождением |
CN110694069B (zh) * | 2019-11-08 | 2022-02-25 | 重庆医科大学附属第二医院 | 一种防治爆发性肝炎的药物 |
CN110898063A (zh) * | 2019-12-06 | 2020-03-24 | 湘北威尔曼制药股份有限公司 | 哌拉西林和舒巴坦的药物组合治疗细菌感染合并乙肝的新适应症 |
CN111494431B (zh) * | 2020-04-28 | 2021-06-22 | 苏州大学 | 益生菌在制备治疗肝脏疾病制剂中的应用 |
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US4322405A (en) | 1981-04-06 | 1982-03-30 | Laboratoires Om Societe Anonyme | Method for treating rheumatoid arthritis |
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US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
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JPH09301878A (ja) | 1996-05-13 | 1997-11-25 | Youshindou:Kk | 腫瘍増殖抑制剤 |
AR022986A1 (es) | 1996-08-12 | 2002-09-04 | Gist Brocades Bv | Produccion y uso de composiciones que comprenden concentraciones altas de actividad de vitamina b12 |
AU738513B2 (en) | 1997-02-28 | 2001-09-20 | University Of Iowa Research Foundation, The | Use of nucleic acids containing unmethylated CpG dinucleotide in the treatment of LPS-associated disorders |
US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
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ATE370740T1 (de) | 1997-05-20 | 2007-09-15 | Ottawa Health Research Inst | Verfahren zur herstellung von nukleinsäurekonstrukten |
US6281191B1 (en) * | 1997-12-29 | 2001-08-28 | Vladimir I. Slesarev | Compositions and methods for treating hepatitis-C |
ATE356630T1 (de) | 1998-04-03 | 2007-04-15 | Univ Iowa Res Found | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
JP4074006B2 (ja) | 1998-06-24 | 2008-04-09 | アサマ化成株式会社 | IgE抗体産生抑制物質の製造方法並びにそれを用いた食品 |
EP1178118A1 (en) | 2000-08-02 | 2002-02-06 | Dsm N.V. | Isolation of microbial oils |
ATE391496T1 (de) | 2001-03-05 | 2008-04-15 | Ortho Mcneil Pharm Inc | Geschmacksmaskierte pharmazeutische formulierungen |
JP3853673B2 (ja) | 2001-03-09 | 2006-12-06 | 森永乳業株式会社 | C型慢性肝炎治療剤 |
EA007232B1 (ru) | 2001-08-17 | 2006-08-25 | Коли Фармасьютикал Гмбх | Иммуностимулирующие олигонуклеотиды, содержащие комбинацию мотивов и обладающие повышенной активностью |
US20030119774A1 (en) | 2001-09-25 | 2003-06-26 | Marianna Foldvari | Compositions and methods for stimulating an immune response |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
GB0203306D0 (en) | 2002-02-12 | 2002-03-27 | Norferm Da | Method |
JP2006507362A (ja) | 2002-10-22 | 2006-03-02 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 癌転移の活性な特異的免疫治療法 |
US7265152B2 (en) | 2002-11-01 | 2007-09-04 | Viropharma Incorporated | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases |
US7674467B2 (en) | 2003-09-03 | 2010-03-09 | Intralytix, Inc. | Salmonella bacteriophage and uses thereof |
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WO2007013613A1 (ja) | 2005-07-29 | 2007-02-01 | Suntory Limited | フコイダン又はフコイダン加水分解生成物と免疫賦活素材とを含む組成物 |
PT2405002E (pt) | 2006-02-15 | 2015-01-05 | Adiutide Pharmaceuticals Gmbh | Composições e métodos para formulações de oligonucleotídeos |
EP1872792A1 (en) | 2006-06-29 | 2008-01-02 | Biotech Tools S.A. | A method for the production of hydrolyzed allergen |
US8304226B2 (en) | 2006-08-22 | 2012-11-06 | Carl Miller | Quality of life of hepatitis C patients with a formulation for administration to the oral mucosa including freeze dried lysate of selected Lactobacillus or Bifidobacterium species and N-acetyl D-glucosamine |
US8007783B2 (en) | 2006-08-22 | 2011-08-30 | Carl Miller | Quality of life for hepatitis C patients with a formulation for administration to the oral mucosa including Lactobacillus delbrueckii subsp. bulgaricus and N-acetyl D-glucosamine |
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EP2804613A4 (en) | 2012-01-16 | 2015-12-09 | Elizabeth Mckenna | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND HEPATIC DISORDERS |
US20140086849A1 (en) | 2012-09-21 | 2014-03-27 | Elizabeth McKenna | Naturally-Occurring CpG Oligonucleotide Compositions and Therapeutic Applications Thereof |
-
2013
- 2013-01-16 EP EP13738189.3A patent/EP2804613A4/en active Pending
- 2013-01-16 WO PCT/US2013/021752 patent/WO2013109635A1/en active Application Filing
- 2013-01-16 SG SG10202013014RA patent/SG10202013014RA/en unknown
- 2013-01-16 JP JP2014552395A patent/JP6632802B2/ja active Active
- 2013-01-16 KR KR1020227009659A patent/KR20220042485A/ko not_active Application Discontinuation
- 2013-01-16 AP AP2014007804A patent/AP2014007804A0/xx unknown
- 2013-01-16 KR KR1020147018038A patent/KR20140121818A/ko not_active IP Right Cessation
- 2013-01-16 SG SG11201402650RA patent/SG11201402650RA/en unknown
- 2013-01-16 CN CN202110783573.6A patent/CN113813294A/zh active Pending
- 2013-01-16 SG SG10201605350UA patent/SG10201605350UA/en unknown
- 2013-01-16 US US13/743,194 patent/US9713630B2/en active Active
- 2013-01-16 EA EA201491081A patent/EA201491081A1/ru unknown
- 2013-01-16 BR BR112014016389A patent/BR112014016389A8/pt not_active Application Discontinuation
- 2013-01-16 KR KR1020207024890A patent/KR20200106088A/ko not_active Application Discontinuation
- 2013-01-16 CN CN201380004625.9A patent/CN104144693A/zh active Pending
- 2013-01-16 CA CA3208225A patent/CA3208225A1/en active Pending
- 2013-01-16 CA CA2860311A patent/CA2860311A1/en active Pending
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