BR112014015578A2 - composições farmacêuticas tópicas compreendendo bexaroteno e um corticosteróide - Google Patents

composições farmacêuticas tópicas compreendendo bexaroteno e um corticosteróide

Info

Publication number
BR112014015578A2
BR112014015578A2 BR112014015578A BR112014015578A BR112014015578A2 BR 112014015578 A2 BR112014015578 A2 BR 112014015578A2 BR 112014015578 A BR112014015578 A BR 112014015578A BR 112014015578 A BR112014015578 A BR 112014015578A BR 112014015578 A2 BR112014015578 A2 BR 112014015578A2
Authority
BR
Brazil
Prior art keywords
bexarotene
corticosteroid
pharmaceutical compositions
topical pharmaceutical
carrier
Prior art date
Application number
BR112014015578A
Other languages
English (en)
Other versions
BR112014015578A8 (pt
Inventor
Willers Christoph
Evers Fritjof
Trommer Hagen
Mallwitz Henning
Fielhauer Sabine
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48781060&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014015578(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP12000077.3A external-priority patent/EP2612665A1/en
Application filed by Almirall Sa filed Critical Almirall Sa
Publication of BR112014015578A2 publication Critical patent/BR112014015578A2/pt
Publication of BR112014015578A8 publication Critical patent/BR112014015578A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

resumo patente de invenção: "composições farmacêuticas tópicas compreendendo bexaroteno e um corticosteróide". a presente invenção descreve composições farmacêuticas tópicas, úteis para o tratamento de distúrbios da pele, que compreendem: a) um bexaroteno, b) pelo menos um corticosteróide ou qualquer sal ou éster farmaceuticamente aceitável do mesmo, e c) um carreador ou um veículo, bem como o uso das mesmas para a fabricação de um medicamento. 21628281v1 1/1 21628281v1
BR112014015578A 2012-01-09 2012-12-18 composições farmacêuticas tópicas compreendendo bexaroteno e um corticosteróide BR112014015578A8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12000077.3A EP2612665A1 (en) 2012-01-09 2012-01-09 Topical pharmaceutical compositions comprising bexarotene and a corticosteroide
US201261585786P 2012-01-12 2012-01-12
US201261598095P 2012-02-13 2012-02-13
EP12000909 2012-02-13
PCT/EP2012/005237 WO2013104399A1 (en) 2012-01-09 2012-12-18 Topical pharmaceutical compositions comprising bexarotene and a corticosteroids

Publications (2)

Publication Number Publication Date
BR112014015578A2 true BR112014015578A2 (pt) 2017-06-13
BR112014015578A8 BR112014015578A8 (pt) 2017-07-04

Family

ID=48781060

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014015578A BR112014015578A8 (pt) 2012-01-09 2012-12-18 composições farmacêuticas tópicas compreendendo bexaroteno e um corticosteróide

Country Status (21)

Country Link
US (1) US20140349981A1 (pt)
EP (1) EP2802321A1 (pt)
JP (1) JP2015503573A (pt)
KR (1) KR20140107370A (pt)
CN (1) CN104053437A (pt)
AU (1) AU2012365658A1 (pt)
BR (1) BR112014015578A8 (pt)
CA (1) CA2857207A1 (pt)
CL (1) CL2014001776A1 (pt)
CO (1) CO7000772A2 (pt)
CR (1) CR20140326A (pt)
EA (1) EA201400806A1 (pt)
GT (1) GT201400146A (pt)
HK (1) HK1198423A1 (pt)
IL (1) IL232765A0 (pt)
MX (1) MX2014007300A (pt)
PE (1) PE20142375A1 (pt)
PH (1) PH12014501573A1 (pt)
SG (1) SG11201403762PA (pt)
WO (1) WO2013104399A1 (pt)
ZA (1) ZA201403483B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4083029A1 (en) 2013-08-20 2022-11-02 University of Washington through its Center for Commercialization Novel and specific inhibitors of cytochrome p450 26 retinoic acid hydroxylase
WO2016205001A1 (en) 2015-06-18 2016-12-22 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases
CN113453670A (zh) * 2018-09-28 2021-09-28 乔·斯图丁 类固醇和大分子的透孔递送
WO2020084548A1 (en) * 2018-10-26 2020-04-30 Viramal Limited Mucoadhesive gel composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4387463B2 (ja) 1997-02-20 2009-12-16 アラーガン、インコーポレイテッド タザロテンおよびコルチコステロイドによる乾癬の処置
CN1210034C (zh) * 2002-12-06 2005-07-13 重庆华邦制药股份有限公司 治疗银屑病的药物组合物
CN1210035C (zh) 2003-09-29 2005-07-13 中国医学科学院皮肤病研究所 治疗银屑病的复方外用药物

Also Published As

Publication number Publication date
JP2015503573A (ja) 2015-02-02
EP2802321A1 (en) 2014-11-19
PE20142375A1 (es) 2015-01-11
US20140349981A1 (en) 2014-11-27
CA2857207A1 (en) 2013-07-18
WO2013104399A1 (en) 2013-07-18
BR112014015578A8 (pt) 2017-07-04
IL232765A0 (en) 2014-07-31
HK1198423A1 (en) 2015-04-24
EA201400806A1 (ru) 2015-02-27
CR20140326A (es) 2015-01-16
CL2014001776A1 (es) 2014-08-29
CN104053437A (zh) 2014-09-17
CO7000772A2 (es) 2014-07-21
GT201400146A (es) 2015-10-12
KR20140107370A (ko) 2014-09-04
AU2012365658A1 (en) 2014-07-03
PH12014501573A1 (en) 2014-10-08
ZA201403483B (en) 2015-06-24
SG11201403762PA (en) 2014-07-30
MX2014007300A (es) 2014-07-28

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]