BR112014013671A2 - pirofosfato inorgânico e usos do mesmo - Google Patents

pirofosfato inorgânico e usos do mesmo

Info

Publication number
BR112014013671A2
BR112014013671A2 BR112014013671A BR112014013671A BR112014013671A2 BR 112014013671 A2 BR112014013671 A2 BR 112014013671A2 BR 112014013671 A BR112014013671 A BR 112014013671A BR 112014013671 A BR112014013671 A BR 112014013671A BR 112014013671 A2 BR112014013671 A2 BR 112014013671A2
Authority
BR
Brazil
Prior art keywords
ppi
addition
medium
inorganic pyrophosphate
fertilization
Prior art date
Application number
BR112014013671A
Other languages
English (en)
Other versions
BR112014013671A8 (pt
Inventor
Sutovsky Peter
Yi Young-Joo
Original Assignee
Univ Missouri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Missouri filed Critical Univ Missouri
Publication of BR112014013671A8 publication Critical patent/BR112014013671A8/pt
Publication of BR112014013671A2 publication Critical patent/BR112014013671A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/43—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0604—Whole embryos; Culture medium therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/061—Sperm cells, spermatogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0612—Germ cells sorting of gametes, e.g. according to sex or motility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)

Abstract

resumo patente de invenção: "pirofosfato inorgânico e usos do mesmo". a presente invenção proporciona um novo e melhorado estimulante aditivo de esperma que compreende uma certa quantidade de pirofosfato inorgânico (ppi). a adição de ppi no meio para a fertilização in vitro de ser humano/animal (ivf) melhora a taxa de fertilização; a adição de ppi no prolongador de sêmen para inseminação artificial de animal de fazenda (ai) pode melhorar as taxas de gravidez; além disso, os ovócitos de mamíferos maturados in vitro em um meio que inclui o ppi alcança a fertilização melhorada e o potencial de desenvolvimento, enquanto que os embriões cultivados em meio suplementado com ppi tem um desenvolvimento melhorado para o blastócito.
BR112014013671A 2011-12-09 2012-12-07 pirofosfato inorgânico e usos do mesmo BR112014013671A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161630345P 2011-12-09 2011-12-09
PCT/US2012/068592 WO2013086431A1 (en) 2011-12-09 2012-12-07 Inorganic pyrophosphate and uses thereof

Publications (2)

Publication Number Publication Date
BR112014013671A8 BR112014013671A8 (pt) 2017-06-13
BR112014013671A2 true BR112014013671A2 (pt) 2017-06-13

Family

ID=48574950

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014013671A BR112014013671A2 (pt) 2011-12-09 2012-12-07 pirofosfato inorgânico e usos do mesmo

Country Status (6)

Country Link
US (2) US8771934B2 (pt)
EP (1) EP2787810A4 (pt)
CN (1) CN104394689A (pt)
BR (1) BR112014013671A2 (pt)
RU (1) RU2626932C2 (pt)
WO (1) WO2013086431A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9361365B2 (en) 2008-05-01 2016-06-07 Primal Fusion Inc. Methods and apparatus for searching of content using semantic synthesis
WO2015183106A1 (en) * 2014-05-29 2015-12-03 Pacific Brands Use of allene oxide synthase for semen preservation and assisted reproduction

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267268A (en) * 1979-03-12 1981-05-12 Nelson Jr Robert A Spermatozoa extenders
US4362246A (en) * 1980-07-14 1982-12-07 Adair Edwin Lloyd Method of treating collected mammal semen and separating sperm into X Y components
US4329337A (en) * 1981-07-29 1982-05-11 The United States Of America As Represented By The Secretary Of Agriculture Turkey semen extender
JPS6027511B2 (ja) * 1982-02-26 1985-06-29 ユニバ−シテイ オブ ジヨ−ジア リサ−チ フアウンデ−シヨン，インコ−ポレ−テツド 無機ピロリン酸塩による細菌生育刺激
EP0230430A4 (en) * 1985-06-12 1989-03-09 Luminis Pty Ltd CULTURE MEDIUM FOR FERTILIZATION -i (IN VITRO) AND TRANSFER OF EMBRYOS.
JP2552582B2 (ja) * 1989-05-10 1996-11-13 アメリカ合衆国 子の性の前選択の方法
US5686114A (en) * 1995-06-02 1997-11-11 University Of Iowa Research Foundation Uses of inorganic pyrophosphates
RU2099025C1 (ru) * 1995-11-10 1997-12-20 Всероссийский научно-исследовательский и технологический институт птицеводства Синтетическая среда для разбавления спермы сельскохозяйственной птицы
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6309815B1 (en) * 1998-08-07 2001-10-30 University Of Kansas Medical Center Composition and method for preparation, storage and activation of large populations of immotile sperm
GB0001172D0 (en) * 2000-01-20 2000-03-08 Res Del International Limited Physiological medium for perfusing, preserving and storing isolated cell tissue and organ samples
EP2258174A3 (en) * 2000-05-09 2012-06-13 Xy, Llc High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
BR0005045A (pt) * 2000-09-28 2002-05-14 Marcos Fernando De Resende Mat Método para sexagem de espermatozóides usando a via clássica do sistema complemento, com eliminação da via alternativa pela inativação da proteina "b"
CA2532376C (en) * 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US7169548B2 (en) * 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
WO2006130884A2 (en) 2005-05-30 2006-12-07 Mirko Predojevic Medium for improving spermatozoa's vitality of domestic mammalian males and man
US8251887B2 (en) * 2009-01-24 2012-08-28 Xihe Li Reproductive technology of low dose semen production and in vitro/in vitro fertilization in domestic animals
US9474591B2 (en) * 2010-06-09 2016-10-25 Xy, Llc Heterogeneous inseminate system
CA2843837A1 (en) * 2011-08-11 2013-02-14 Androgenix Ltd Methods and compositions for improving sperm functionality

Also Published As

Publication number Publication date
RU2014127863A (ru) 2016-01-27
EP2787810A4 (en) 2015-05-27
US10070889B2 (en) 2018-09-11
US8771934B2 (en) 2014-07-08
EP2787810A1 (en) 2014-10-15
US20140350329A1 (en) 2014-11-27
WO2013086431A1 (en) 2013-06-13
BR112014013671A8 (pt) 2017-06-13
US20130164732A1 (en) 2013-06-27
CN104394689A (zh) 2015-03-04
RU2626932C2 (ru) 2017-08-02

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2492 DE 09/10/2018.

B350 Update of information on the portal [chapter 15.35 patent gazette]