BR112014006788A2 - derivados de metanossulfonamida substituídos com arila ou n-heteroarila como ligantes de receptor vaniloide - Google Patents
derivados de metanossulfonamida substituídos com arila ou n-heteroarila como ligantes de receptor vaniloideInfo
- Publication number
- BR112014006788A2 BR112014006788A2 BR112014006788A BR112014006788A BR112014006788A2 BR 112014006788 A2 BR112014006788 A2 BR 112014006788A2 BR 112014006788 A BR112014006788 A BR 112014006788A BR 112014006788 A BR112014006788 A BR 112014006788A BR 112014006788 A2 BR112014006788 A2 BR 112014006788A2
- Authority
- BR
- Brazil
- Prior art keywords
- aryl
- heteroaryl substituted
- receptor ligands
- methanesulfonamide derivatives
- substituted methanesulfonamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P1/12—Antidiarrhoeals
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
Abstract
resumo patente de invenção: "derivados de metanossulfonamida substituídos com arila ou n-heteroarila como ligantes de receptor vaniloide". a invenção refere-se a derivados de metanossulfonamida de fórmula (i) substituídos com arila ou n-heteroarila como ligantes de receptor vaniloide, a composições farmacêuticas contendo esses compostos e também a esses compostos para uso no tratamento e/ou profilaxia de dor e doenças e/ou distúrbios adicionais.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11007807 | 2011-09-26 | ||
PCT/EP2012/068877 WO2013045447A1 (en) | 2011-09-26 | 2012-09-25 | Aryl or n-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014006788A2 true BR112014006788A2 (pt) | 2017-06-13 |
Family
ID=46888474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014006788A BR112014006788A2 (pt) | 2011-09-26 | 2012-09-25 | derivados de metanossulfonamida substituídos com arila ou n-heteroarila como ligantes de receptor vaniloide |
Country Status (13)
Country | Link |
---|---|
US (1) | US8937092B2 (pt) |
EP (1) | EP2760835A1 (pt) |
JP (1) | JP2014531451A (pt) |
KR (1) | KR20140074363A (pt) |
CN (1) | CN103958472A (pt) |
AR (1) | AR088002A1 (pt) |
AU (1) | AU2012314587A1 (pt) |
BR (1) | BR112014006788A2 (pt) |
CA (1) | CA2849960A1 (pt) |
HK (1) | HK1200456A1 (pt) |
MX (1) | MX2014003455A (pt) |
TW (1) | TW201317214A (pt) |
WO (1) | WO2013045447A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015004035A1 (en) * | 2013-07-09 | 2015-01-15 | Lonza Ltd | Method for preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from trifluoroacetylacetic acid |
CA2953019A1 (en) * | 2014-06-26 | 2015-12-30 | Lonza Ltd | Method for preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2- ones from 1,1,1-trifluoroacetone |
JP6422589B2 (ja) | 2014-11-24 | 2018-11-14 | メディフロン・ディービーティー・インコーポレイテッド | バニロイド受容体リガンドiiとしての置換されたオキサゾール系およびチアゾール系カルボキサミドおよび尿素誘導体 |
EP3130589A1 (en) | 2015-08-13 | 2017-02-15 | Grünenthal GmbH | Heterocyclic aza compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7135575B2 (en) | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
JP2005314407A (ja) | 2004-03-31 | 2005-11-10 | Nippon Nohyaku Co Ltd | 新規なハロアルキルスルホンアニリド誘導体、除草剤及びその使用方法並びにその中間体 |
JP5323485B2 (ja) | 2005-10-19 | 2013-10-23 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 新規バニロイド受容体リガンド及医薬の製造へのその使用 |
CA2791680A1 (en) * | 2010-03-01 | 2011-09-09 | Myrexis, Inc. | Compounds and therapeutic uses thereof |
-
2012
- 2012-09-25 MX MX2014003455A patent/MX2014003455A/es not_active Application Discontinuation
- 2012-09-25 AR ARP120103517A patent/AR088002A1/es unknown
- 2012-09-25 TW TW101135070A patent/TW201317214A/zh unknown
- 2012-09-25 KR KR1020147011303A patent/KR20140074363A/ko not_active Application Discontinuation
- 2012-09-25 WO PCT/EP2012/068877 patent/WO2013045447A1/en active Application Filing
- 2012-09-25 JP JP2014531270A patent/JP2014531451A/ja not_active Withdrawn
- 2012-09-25 US US13/626,315 patent/US8937092B2/en not_active Expired - Fee Related
- 2012-09-25 CN CN201280046993.5A patent/CN103958472A/zh active Pending
- 2012-09-25 AU AU2012314587A patent/AU2012314587A1/en not_active Abandoned
- 2012-09-25 CA CA2849960A patent/CA2849960A1/en not_active Abandoned
- 2012-09-25 EP EP12762014.4A patent/EP2760835A1/en not_active Withdrawn
- 2012-09-25 BR BR112014006788A patent/BR112014006788A2/pt unknown
-
2015
- 2015-01-29 HK HK15101022.3A patent/HK1200456A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR20140074363A (ko) | 2014-06-17 |
US20130079377A1 (en) | 2013-03-28 |
WO2013045447A1 (en) | 2013-04-04 |
MX2014003455A (es) | 2014-06-04 |
HK1200456A1 (en) | 2015-08-07 |
US8937092B2 (en) | 2015-01-20 |
AU2012314587A1 (en) | 2014-03-06 |
EP2760835A1 (en) | 2014-08-06 |
AR088002A1 (es) | 2014-04-30 |
CA2849960A1 (en) | 2013-04-04 |
JP2014531451A (ja) | 2014-11-27 |
CN103958472A (zh) | 2014-07-30 |
TW201317214A (zh) | 2013-05-01 |
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