BR112014005864A2 - compostos de beta-lactama para tratar diabetes - Google Patents
compostos de beta-lactama para tratar diabetesInfo
- Publication number
- BR112014005864A2 BR112014005864A2 BR112014005864A BR112014005864A BR112014005864A2 BR 112014005864 A2 BR112014005864 A2 BR 112014005864A2 BR 112014005864 A BR112014005864 A BR 112014005864A BR 112014005864 A BR112014005864 A BR 112014005864A BR 112014005864 A2 BR112014005864 A2 BR 112014005864A2
- Authority
- BR
- Brazil
- Prior art keywords
- beta
- treat diabetes
- lactam compounds
- diabetes
- lactam
- Prior art date
Links
- -1 beta-lactam compounds Chemical class 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 1
- 229960000723 ampicillin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
resumo são fornecidas composições e métodos compreendendo ampicilina ou sais e derivado destes para o tratamento ou atraso no início de ação de diabetes tipo i.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161537105P | 2011-09-21 | 2011-09-21 | |
PCT/IL2012/050378 WO2013042121A1 (en) | 2011-09-21 | 2012-09-20 | Beta-lactam compounds for treating diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014005864A2 true BR112014005864A2 (pt) | 2017-03-28 |
Family
ID=47913973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014005864A BR112014005864A2 (pt) | 2011-09-21 | 2012-09-20 | compostos de beta-lactama para tratar diabetes |
Country Status (8)
Country | Link |
---|---|
US (1) | US9474744B2 (pt) |
EP (1) | EP2758054B1 (pt) |
CN (1) | CN104023721A (pt) |
AU (1) | AU2012311050A1 (pt) |
BR (1) | BR112014005864A2 (pt) |
CA (1) | CA2850558A1 (pt) |
HK (1) | HK1201466A1 (pt) |
WO (1) | WO2013042121A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2020210983B2 (en) * | 2019-01-23 | 2024-05-16 | Glycolysis Biomed Co., Ltd | Beta-lactam compounds or salts thereof for use in long-acting prevention or treatment of a glucose metabolism disorder |
JOP20210298A1 (ar) | 2019-05-14 | 2023-01-30 | Provention Bio Inc | طرق وتركيبات للوقاية من مرض السكري من النوع الأول |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA94128B (en) | 1993-02-01 | 1994-08-19 | Univ New York State Res Found | Process for the preparation of taxane derivatives and betalactam intermediates therefor |
WO1997021675A1 (en) | 1995-12-08 | 1997-06-19 | Smithkline Beecham Plc | Monocyclic beta-lactame derivatives for treatment of atherosclerosis |
US6130087A (en) | 1996-10-07 | 2000-10-10 | Fordham University | Methods for generating cytotoxic T cells in vitro |
US6255467B1 (en) | 1997-11-06 | 2001-07-03 | Pathobiotek Diagnostics Inc. | Human blood bacterium |
LV12403B (lv) | 1998-06-10 | 2000-02-20 | Latvijas Organiskās Sintēzes Institūts | Citotoksiskie penicilānskābes atvasinājumi |
US6015809A (en) * | 1998-08-17 | 2000-01-18 | American Home Products Corporation | Photocyclized rapamycin |
AU781218B2 (en) | 1999-08-16 | 2005-05-12 | Revaax Pharmaceuticals, Llc | Pharmaceutical compositions comprising clavulanic acid or derivative thereof for the treatment of behavioral diseases |
US7638326B2 (en) | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
AU2003202942A1 (en) | 2002-01-17 | 2003-09-02 | R.E.D. Laboratories, N.V./S.A. | Methods of treatment of chronic immune disease |
US7026472B2 (en) | 2002-05-06 | 2006-04-11 | University Of South Florida | Methods for preventing and treating cancer using N-thiolated β-lactam compounds and analogs thereof |
US7250438B2 (en) | 2004-06-08 | 2007-07-31 | Nereus Pharmaceuticals, Inc. | Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams |
ES2357800T3 (es) | 2004-10-30 | 2011-04-29 | Universidad Del Pais Vasco-Euskal Herriko Unibersitatea | Ciclopéptidos rgd beta-lactámicos que contienen giros gamma. |
CA2611577A1 (en) | 2005-06-07 | 2007-09-07 | Foamix Ltd. | Antibiotic kit and composition and uses thereof |
KR100697312B1 (ko) | 2005-08-31 | 2007-03-20 | 한국생명공학연구원 | 세프트리악손을 포함하는 stat3 활성 저해 활성을가지는 조성물 |
WO2010057647A2 (en) * | 2008-11-21 | 2010-05-27 | Universita' Degli Studi Di Milano | Methods and compositions for the diagnosis and treatment of diabetes |
CN101524517A (zh) | 2009-04-28 | 2009-09-09 | 李红彬 | 一种治疗上呼吸道感染的中西复合药物 |
WO2011047153A1 (en) * | 2009-10-15 | 2011-04-21 | President And Fellows Of Harvard College | Methods for modulating autoimmunity |
WO2012103456A2 (en) | 2011-01-27 | 2012-08-02 | Board Of Regents, The University Of Texas System | Polycyclic beta lactam derivatives for the treatment of cancer |
-
2012
- 2012-09-20 AU AU2012311050A patent/AU2012311050A1/en not_active Abandoned
- 2012-09-20 EP EP12833374.7A patent/EP2758054B1/en not_active Not-in-force
- 2012-09-20 US US14/346,219 patent/US9474744B2/en not_active Expired - Fee Related
- 2012-09-20 BR BR112014005864A patent/BR112014005864A2/pt not_active IP Right Cessation
- 2012-09-20 CA CA2850558A patent/CA2850558A1/en not_active Abandoned
- 2012-09-20 WO PCT/IL2012/050378 patent/WO2013042121A1/en active Application Filing
- 2012-09-20 CN CN201280046027.3A patent/CN104023721A/zh active Pending
-
2015
- 2015-03-02 HK HK15102059.7A patent/HK1201466A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2850558A1 (en) | 2013-03-28 |
CN104023721A (zh) | 2014-09-03 |
HK1201466A1 (en) | 2015-09-04 |
US20140234282A1 (en) | 2014-08-21 |
AU2012311050A1 (en) | 2014-03-06 |
EP2758054A1 (en) | 2014-07-30 |
EP2758054B1 (en) | 2017-04-12 |
WO2013042121A1 (en) | 2013-03-28 |
US9474744B2 (en) | 2016-10-25 |
EP2758054A4 (en) | 2015-03-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/43 (2006.01), A61K 35/17 (2015.01), A61K 3 |