BR112013023539A2 - derivados de isoxazolidina - Google Patents

derivados de isoxazolidina

Info

Publication number: BR112013023539A2
Authority: BR; Brazil
Prior art keywords: isoxazolidine derivatives; isoxazolidine; derivatives
Prior art date: 2011-03-15

Application number

BR112013023539A

Other languages

English (en)

Other versions

BR112013023539B1 (pt

Inventor

Andrea Rizzi

Eleonora Ghidini

Original Assignee

Chiesi Farma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-03-15

Filing date

2012-03-14

Publication date

2017-01-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44351355&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013023539(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-03-14 Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa

2017-01-24 Publication of BR112013023539A2 publication Critical patent/BR112013023539A2/pt

2022-03-03 Publication of BR112013023539B1 publication Critical patent/BR112013023539B1/pt

Links

150000002546 isoxazolidines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0068—Nitrogen and oxygen at position 16(17)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)

BR112013023539-0A 2011-03-15 2012-03-14 Composto, composição farmacêutica, combinação de um composto, uso de um composto e dispositivo BR112013023539B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP11158230		2011-03-15
EP11158230.0		2011-03-15
PCT/EP2012/054439 WO2012123482A2 (en)	2011-03-15	2012-03-14	Isoxazolidine derivatives

Publications (2)

Publication Number	Publication Date
BR112013023539A2 true BR112013023539A2 (pt)	2017-01-24
BR112013023539B1 BR112013023539B1 (pt)	2022-03-03

Family

ID=44351355

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR112013023539-0A BR112013023539B1 (pt)	2011-03-15	2012-03-14	Composto, composição farmacêutica, combinação de um composto, uso de um composto e dispositivo

Country Status (22)

Country	Link
US (3)	US20120234316A1 (pt)
EP (2)	EP2716648B1 (pt)
JP (1)	JP6053700B2 (pt)
KR (1)	KR101956937B1 (pt)
CN (1)	CN103391945B (pt)
AR (1)	AR085817A1 (pt)
AU (1)	AU2012228334B2 (pt)
BR (1)	BR112013023539B1 (pt)
CA (1)	CA2850081C (pt)
CL (1)	CL2013002629A1 (pt)
EA (1)	EA028904B1 (pt)
GE (1)	GEP201606566B (pt)
IL (1)	IL228382A (pt)
MX (1)	MX345400B (pt)
MY (1)	MY194140A (pt)
PE (1)	PE20140890A1 (pt)
SG (1)	SG193262A1 (pt)
TN (1)	TN2013000313A1 (pt)
TW (1)	TWI658047B (pt)
UA (1)	UA113508C2 (pt)
WO (1)	WO2012123482A2 (pt)
ZA (2)	ZA201306881B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2843782A1 (en)	2011-08-01	2013-02-07	Chiesi Farmaceutici S.P.A.	Anti-inflammatory steroids condensed in position 16,17 with pyrrolidine ring
US9155747B2 (en) *	2012-09-13	2015-10-13	Chiesi Farmaceutici S.P.A.	Isoxazolidine derivatives
EP2902382A1 (en) *	2014-01-30	2015-08-05	Fundació Institut de Recerca Biomèdica IRB (Barcelona)	Primary hydroxylamines and uses thereof
JP6756435B2 (ja) *	2014-03-31	2020-09-16	ザスクリプスリサーチインスティテュート	Ｔｒａｉｌ誘導のためのファーマコフォア
EA202092492A1 (ru)	2014-09-03	2021-07-30	Ризен Фармасьютикалз Са	Способ лечения и композиции, содержащие двойной ингибитор киназ pi3k дельта-гамма и кортикостероид
CN104262440B (zh) *	2014-09-10	2016-08-17	江西赣亮医药原料有限公司	一种16ɑ-羟基***龙的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL31997A (en) *	1968-05-03	1974-03-14	Lepetit Spa	Process for the preparation of pregnano(17alpha,16alpha-d)oxazolines and 16alpha,21-dihydroxy-17alpha-aminopregnanes
US4018774A (en)	1976-02-13	1977-04-19	E. R. Squibb & Sons, Inc.	Steroidal [16α,17-d]isoxazolidines
AR224124A1 (es) *	1978-04-05	1981-10-30	Syntex Inc	Procedimiento para preparar 4-halo-pregna-1,4-dieno-3,20-dionas
WO2005028495A1 (en) *	2003-09-24	2005-03-31	Glaxo Group Limited	Anti-inflammatory glucocorticoids
GB0415747D0 (en) *	2004-07-14	2004-08-18	Novartis Ag	Organic compounds
CA2592971A1 (en)	2005-01-03	2006-07-13	Myriad Genetics Inc.	Method of treating brain cancer
MX2010005861A (es) *	2007-11-30	2010-06-11	Pfizer Ltd	Agonistas novedosos de los receptores de glucocorticoides.
RU2010133722A (ru) *	2008-02-27	2012-04-10	Астразенека Аб (Se)	16-альфа, 17-альфа-ацетальглюкокортикостероидные производные и их применение
CN101926805A (zh) *	2009-06-24	2010-12-29	天津金耀集团有限公司	一种含有16,17异恶唑烷类甾体化合物的药物组合物
WO2011029547A2 (en) *	2009-09-11	2011-03-17	Chiesi Farmaceutici S.P.A.	Pregnane derivatives condensed in the 16, 17 position with an n-substituted isoxazolidine ring as anti-inflammatory agents
TW201139369A (en)	2010-02-05	2011-11-16	Chiesi Farma Spa	Pyrrolidine derivatives
WO2012123493A2 (en)	2011-03-15	2012-09-20	Chiesi Farmaceutici S.P.A.	Isoxazolidine derivatives
CA2843782A1 (en)	2011-08-01	2013-02-07	Chiesi Farmaceutici S.P.A.	Anti-inflammatory steroids condensed in position 16,17 with pyrrolidine ring
US9155747B2 (en)	2012-09-13	2015-10-13	Chiesi Farmaceutici S.P.A.	Isoxazolidine derivatives

2012
- 2012-03-14 CA CA2850081A patent/CA2850081C/en active Active
- 2012-03-14 CN CN201280008928.3A patent/CN103391945B/zh not_active Expired - Fee Related
- 2012-03-14 GE GEAP201213223A patent/GEP201606566B/en unknown
- 2012-03-14 JP JP2013558416A patent/JP6053700B2/ja not_active Expired - Fee Related
- 2012-03-14 AU AU2012228334A patent/AU2012228334B2/en not_active Ceased
- 2012-03-14 TW TW101108588A patent/TWI658047B/zh not_active IP Right Cessation
- 2012-03-14 BR BR112013023539-0A patent/BR112013023539B1/pt not_active IP Right Cessation
- 2012-03-14 MX MX2013010354A patent/MX345400B/es active IP Right Grant
- 2012-03-14 KR KR1020137022976A patent/KR101956937B1/ko active IP Right Grant
- 2012-03-14 EP EP13197855.3A patent/EP2716648B1/en active Active
- 2012-03-14 WO PCT/EP2012/054439 patent/WO2012123482A2/en active Application Filing
- 2012-03-14 EA EA201391173A patent/EA028904B1/ru not_active IP Right Cessation
- 2012-03-14 UA UAA201310933A patent/UA113508C2/uk unknown
- 2012-03-14 SG SG2013065974A patent/SG193262A1/en unknown
- 2012-03-14 MY MYPI2013002925A patent/MY194140A/en unknown
- 2012-03-14 EP EP12711601.0A patent/EP2686332A2/en not_active Withdrawn
- 2012-03-14 AR ARP120100843A patent/AR085817A1/es active IP Right Grant
- 2012-03-14 PE PE2013002015A patent/PE20140890A1/es active IP Right Grant
- 2012-03-15 US US13/421,150 patent/US20120234316A1/en not_active Abandoned
2013
- 2013-07-24 TN TNP2013000313A patent/TN2013000313A1/fr unknown
- 2013-09-12 CL CL2013002629A patent/CL2013002629A1/es unknown
- 2013-09-12 IL IL228382A patent/IL228382A/en active IP Right Grant
- 2013-09-12 ZA ZA2013/06881A patent/ZA201306881B/en unknown
2014
- 2014-07-31 ZA ZA2014/05681A patent/ZA201405681B/en unknown
- 2014-11-10 US US14/537,184 patent/US9845337B2/en active Active
2017
- 2017-11-08 US US15/807,066 patent/US10280193B2/en active Active

Also Published As

Publication number	Publication date
KR101956937B1 (ko)	2019-03-11
AR085817A1 (es)	2013-10-30
EA201391173A1 (ru)	2014-01-30
ZA201405681B (en)	2015-12-23
CN103391945A (zh)	2013-11-13
US9845337B2 (en)	2017-12-19
SG193262A1 (en)	2013-10-30
EA028904B1 (ru)	2018-01-31
MX345400B (es)	2017-01-30
IL228382A0 (en)	2013-12-31
CA2850081C (en)	2020-01-07
EP2716648B1 (en)	2017-06-14
TW201247697A (en)	2012-12-01
ZA201306881B (en)	2014-11-26
KR20140006016A (ko)	2014-01-15
IL228382A (en)	2017-08-31
TWI658047B (zh)	2019-05-01
PE20140890A1 (es)	2014-08-05
US20180066010A1 (en)	2018-03-08
US20150057257A1 (en)	2015-02-26
WO2012123482A2 (en)	2012-09-20
MY194140A (en)	2022-11-14
EP2716648A1 (en)	2014-04-09
JP6053700B2 (ja)	2016-12-27
UA113508C2 (xx)	2017-02-10
WO2012123482A3 (en)	2013-02-07
GEP201606566B (en)	2016-11-10
CN103391945B (zh)	2016-11-09
CL2013002629A1 (es)	2014-01-10
NZ615423A (en)	2015-08-28
US20120234316A1 (en)	2012-09-20
AU2012228334A1 (en)	2013-10-03
CA2850081A1 (en)	2012-09-20
AU2012228334B2 (en)	2017-03-23
JP2014508181A (ja)	2014-04-03
EP2686332A2 (en)	2014-01-22
US10280193B2 (en)	2019-05-07
BR112013023539B1 (pt)	2022-03-03
MX2013010354A (es)	2013-12-06
TN2013000313A1 (en)	2015-01-20

Legal Events

Date	Code	Title	Description
2018-01-23	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-03	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-07-02	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-10-29	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2020-10-06	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2021-06-08	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2021-10-05	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2022-01-11	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2022-03-03	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/03/2012, OBSERVADAS AS CONDICOES LEGAIS.
2024-01-09	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 12A ANUIDADE.
2024-04-30	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2766 DE 09-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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