BR112012026224A2 - métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia - Google Patents

métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia

Info

Publication number
BR112012026224A2
BR112012026224A2 BR112012026224A BR112012026224A BR112012026224A2 BR 112012026224 A2 BR112012026224 A2 BR 112012026224A2 BR 112012026224 A BR112012026224 A BR 112012026224A BR 112012026224 A BR112012026224 A BR 112012026224A BR 112012026224 A2 BR112012026224 A2 BR 112012026224A2
Authority
BR
Brazil
Prior art keywords
disease
methods
effectiveness
evaluating
treating alzheimer
Prior art date
Application number
BR112012026224A
Other languages
English (en)
Inventor
Norman R Relkin
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44761427&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012026224(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of BR112012026224A2 publication Critical patent/BR112012026224A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia. a presente invenção se refere ao uso de monitoramento de mri de taxa de dilatação ventricular como uma medida objetiva para o propósito de avaliar a progressão da doença em indivíduos que sofrem do mal de alzheimer e para o propósito de determinar a eficácia terapêutica de um regime de tratamento para indivíduos com alzheimer. métodos para tratar mal de alzheimer e monitorar a eficácia terapêutica são fornecidos.
BR112012026224A 2010-04-13 2011-04-13 métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia BR112012026224A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32373910P 2010-04-13 2010-04-13
PCT/US2011/032232 WO2011130355A1 (en) 2010-04-13 2011-04-13 Use of ventricular enlargement rate in intravenous immunoglobulin treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
BR112012026224A2 true BR112012026224A2 (pt) 2016-07-12

Family

ID=44761427

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012026224A BR112012026224A2 (pt) 2010-04-13 2011-04-13 métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia

Country Status (17)

Country Link
US (2) US8066993B2 (pt)
EP (1) EP2451348A4 (pt)
JP (2) JP2013509985A (pt)
KR (1) KR20130114563A (pt)
CN (1) CN102946799A (pt)
AR (1) AR081534A1 (pt)
AU (1) AU2011240556B2 (pt)
BR (1) BR112012026224A2 (pt)
CA (1) CA2795651A1 (pt)
CL (1) CL2012002852A1 (pt)
CO (1) CO6592030A2 (pt)
EA (1) EA201291040A1 (pt)
IL (1) IL222245A0 (pt)
MX (1) MX2012011924A (pt)
SG (1) SG184820A1 (pt)
TW (1) TW201138807A (pt)
WO (1) WO2011130355A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090280114A1 (en) * 2002-04-12 2009-11-12 Ramot At Tel Aviv University Ltd. Prevention of brain inflammation as a result of induced autoimmune response
EP2742855A1 (en) * 2012-12-11 2014-06-18 Friedrich-Alexander-Universität Erlangen-Nürnberg Brain functional magnetic resonance activity is associated with response to tumor necrosis factor inhibition
PT2994160T (pt) * 2013-05-06 2019-08-07 Baxalta Inc Tratamento de sub-populações com doença de alzheimer com imunoglobulina g combinada
RU2724190C2 (ru) * 2014-02-08 2020-06-23 Дженентек, Инк. Способы лечения болезни альцгеймера
JP6548615B2 (ja) * 2016-08-23 2019-07-24 富士フイルム株式会社 磁場歪み算出装置、方法およびプログラム
CN108830830A (zh) * 2018-05-11 2018-11-16 深圳博脑医疗科技有限公司 一种脑萎缩程度的定量检测方法、检测装置及终端设备
KR102276545B1 (ko) * 2019-09-05 2021-07-15 고려대학교 산학협력단 Ct 영상 기반 부위별 대뇌 피질 수축율 예측 방법 및 장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003064395A1 (fr) * 2002-01-31 2003-08-07 President Of National Center Of Neurology And Psychiatry Agents preventifs et therapeutiques destines a lutter contre des maladies neurodegeneratives
BRPI0517672A (pt) * 2004-11-05 2008-10-14 Wyeth Corp modalidades de formação de imagens para seleção terapêutica de doença de alzheimer
PL2182983T3 (pl) 2007-07-27 2014-10-31 Janssen Alzheimer Immunotherap Leczenie chorób amyloidowych z wykorzystaniem humanizowanych przeciwciał specyficznych względem Abeta
EP2522755B1 (en) * 2007-08-13 2014-04-02 Baxter International Inc. IVIG modulation of chemokines for treatment of Multiple Sclerosis, Alzheimer's disease, and Parkinson's disease
JO3076B1 (ar) * 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe

Also Published As

Publication number Publication date
SG184820A1 (en) 2012-11-29
EP2451348A1 (en) 2012-05-16
CO6592030A2 (es) 2013-01-02
US8066993B2 (en) 2011-11-29
CA2795651A1 (en) 2011-10-20
TW201138807A (en) 2011-11-16
US20110251479A1 (en) 2011-10-13
CN102946799A (zh) 2013-02-27
EA201291040A1 (ru) 2013-04-30
MX2012011924A (es) 2013-03-05
EP2451348A4 (en) 2013-07-31
KR20130114563A (ko) 2013-10-17
US8722042B2 (en) 2014-05-13
JP2013509985A (ja) 2013-03-21
AU2011240556A1 (en) 2012-04-19
JP2012210413A (ja) 2012-11-01
WO2011130355A1 (en) 2011-10-20
CL2012002852A1 (es) 2013-04-05
AR081534A1 (es) 2012-10-03
US20120071747A1 (en) 2012-03-22
AU2011240556B2 (en) 2012-06-21
IL222245A0 (en) 2012-12-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A E 5A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.