BR112012026224A2 - métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia - Google Patents
métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapiaInfo
- Publication number
- BR112012026224A2 BR112012026224A2 BR112012026224A BR112012026224A BR112012026224A2 BR 112012026224 A2 BR112012026224 A2 BR 112012026224A2 BR 112012026224 A BR112012026224 A BR 112012026224A BR 112012026224 A BR112012026224 A BR 112012026224A BR 112012026224 A2 BR112012026224 A2 BR 112012026224A2
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- methods
- effectiveness
- evaluating
- treating alzheimer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia. a presente invenção se refere ao uso de monitoramento de mri de taxa de dilatação ventricular como uma medida objetiva para o propósito de avaliar a progressão da doença em indivíduos que sofrem do mal de alzheimer e para o propósito de determinar a eficácia terapêutica de um regime de tratamento para indivíduos com alzheimer. métodos para tratar mal de alzheimer e monitorar a eficácia terapêutica são fornecidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32373910P | 2010-04-13 | 2010-04-13 | |
PCT/US2011/032232 WO2011130355A1 (en) | 2010-04-13 | 2011-04-13 | Use of ventricular enlargement rate in intravenous immunoglobulin treatment of alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012026224A2 true BR112012026224A2 (pt) | 2016-07-12 |
Family
ID=44761427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012026224A BR112012026224A2 (pt) | 2010-04-13 | 2011-04-13 | métodos para tratar mal de alzheimer e para avaliar a eficácia de uma terapia |
Country Status (17)
Country | Link |
---|---|
US (2) | US8066993B2 (pt) |
EP (1) | EP2451348A4 (pt) |
JP (2) | JP2013509985A (pt) |
KR (1) | KR20130114563A (pt) |
CN (1) | CN102946799A (pt) |
AR (1) | AR081534A1 (pt) |
AU (1) | AU2011240556B2 (pt) |
BR (1) | BR112012026224A2 (pt) |
CA (1) | CA2795651A1 (pt) |
CL (1) | CL2012002852A1 (pt) |
CO (1) | CO6592030A2 (pt) |
EA (1) | EA201291040A1 (pt) |
IL (1) | IL222245A0 (pt) |
MX (1) | MX2012011924A (pt) |
SG (1) | SG184820A1 (pt) |
TW (1) | TW201138807A (pt) |
WO (1) | WO2011130355A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090280114A1 (en) * | 2002-04-12 | 2009-11-12 | Ramot At Tel Aviv University Ltd. | Prevention of brain inflammation as a result of induced autoimmune response |
EP2742855A1 (en) * | 2012-12-11 | 2014-06-18 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Brain functional magnetic resonance activity is associated with response to tumor necrosis factor inhibition |
PT2994160T (pt) * | 2013-05-06 | 2019-08-07 | Baxalta Inc | Tratamento de sub-populações com doença de alzheimer com imunoglobulina g combinada |
RU2724190C2 (ru) * | 2014-02-08 | 2020-06-23 | Дженентек, Инк. | Способы лечения болезни альцгеймера |
JP6548615B2 (ja) * | 2016-08-23 | 2019-07-24 | 富士フイルム株式会社 | 磁場歪み算出装置、方法およびプログラム |
CN108830830A (zh) * | 2018-05-11 | 2018-11-16 | 深圳博脑医疗科技有限公司 | 一种脑萎缩程度的定量检测方法、检测装置及终端设备 |
KR102276545B1 (ko) * | 2019-09-05 | 2021-07-15 | 고려대학교 산학협력단 | Ct 영상 기반 부위별 대뇌 피질 수축율 예측 방법 및 장치 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003064395A1 (fr) * | 2002-01-31 | 2003-08-07 | President Of National Center Of Neurology And Psychiatry | Agents preventifs et therapeutiques destines a lutter contre des maladies neurodegeneratives |
BRPI0517672A (pt) * | 2004-11-05 | 2008-10-14 | Wyeth Corp | modalidades de formação de imagens para seleção terapêutica de doença de alzheimer |
PL2182983T3 (pl) | 2007-07-27 | 2014-10-31 | Janssen Alzheimer Immunotherap | Leczenie chorób amyloidowych z wykorzystaniem humanizowanych przeciwciał specyficznych względem Abeta |
EP2522755B1 (en) * | 2007-08-13 | 2014-04-02 | Baxter International Inc. | IVIG modulation of chemokines for treatment of Multiple Sclerosis, Alzheimer's disease, and Parkinson's disease |
JO3076B1 (ar) * | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
-
2011
- 2011-04-13 MX MX2012011924A patent/MX2012011924A/es not_active Application Discontinuation
- 2011-04-13 KR KR1020127029420A patent/KR20130114563A/ko not_active Application Discontinuation
- 2011-04-13 WO PCT/US2011/032232 patent/WO2011130355A1/en active Application Filing
- 2011-04-13 EA EA201291040A patent/EA201291040A1/ru unknown
- 2011-04-13 TW TW100112770A patent/TW201138807A/zh unknown
- 2011-04-13 AU AU2011240556A patent/AU2011240556B2/en not_active Ceased
- 2011-04-13 EP EP11769496.8A patent/EP2451348A4/en not_active Withdrawn
- 2011-04-13 JP JP2012539095A patent/JP2013509985A/ja active Pending
- 2011-04-13 CA CA2795651A patent/CA2795651A1/en not_active Abandoned
- 2011-04-13 SG SG2012075479A patent/SG184820A1/en unknown
- 2011-04-13 CN CN2011800191696A patent/CN102946799A/zh active Pending
- 2011-04-13 US US13/086,285 patent/US8066993B2/en not_active Expired - Fee Related
- 2011-04-13 BR BR112012026224A patent/BR112012026224A2/pt not_active IP Right Cessation
- 2011-04-14 AR ARP110101285A patent/AR081534A1/es unknown
- 2011-10-17 US US13/274,886 patent/US8722042B2/en not_active Expired - Fee Related
-
2012
- 2012-05-21 JP JP2012115203A patent/JP2012210413A/ja active Pending
- 2012-10-09 IL IL222245A patent/IL222245A0/en unknown
- 2012-10-11 CL CL2012002852A patent/CL2012002852A1/es unknown
- 2012-11-13 CO CO12203213A patent/CO6592030A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SG184820A1 (en) | 2012-11-29 |
EP2451348A1 (en) | 2012-05-16 |
CO6592030A2 (es) | 2013-01-02 |
US8066993B2 (en) | 2011-11-29 |
CA2795651A1 (en) | 2011-10-20 |
TW201138807A (en) | 2011-11-16 |
US20110251479A1 (en) | 2011-10-13 |
CN102946799A (zh) | 2013-02-27 |
EA201291040A1 (ru) | 2013-04-30 |
MX2012011924A (es) | 2013-03-05 |
EP2451348A4 (en) | 2013-07-31 |
KR20130114563A (ko) | 2013-10-17 |
US8722042B2 (en) | 2014-05-13 |
JP2013509985A (ja) | 2013-03-21 |
AU2011240556A1 (en) | 2012-04-19 |
JP2012210413A (ja) | 2012-11-01 |
WO2011130355A1 (en) | 2011-10-20 |
CL2012002852A1 (es) | 2013-04-05 |
AR081534A1 (es) | 2012-10-03 |
US20120071747A1 (en) | 2012-03-22 |
AU2011240556B2 (en) | 2012-06-21 |
IL222245A0 (en) | 2012-12-31 |
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Legal Events
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A E 5A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |