BR112012025844A2 - uso de nanofibras snag - Google Patents

uso de nanofibras snag

Info

Publication number
BR112012025844A2
BR112012025844A2 BR112012025844A BR112012025844A BR112012025844A2 BR 112012025844 A2 BR112012025844 A2 BR 112012025844A2 BR 112012025844 A BR112012025844 A BR 112012025844A BR 112012025844 A BR112012025844 A BR 112012025844A BR 112012025844 A2 BR112012025844 A2 BR 112012025844A2
Authority
BR
Brazil
Prior art keywords
compositions
snag nanofibers
bacterial
bacterial infection
treating
Prior art date
Application number
BR112012025844A
Other languages
English (en)
Inventor
N Vournakis John
Finkielsztein Sergio
Original Assignee
Marine Polymer Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marine Polymer Tech Inc filed Critical Marine Polymer Tech Inc
Publication of BR112012025844A2 publication Critical patent/BR112012025844A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

métodos para o tratamento de uma infecção bacteriana e de uma doença associada a uma infecção bacteriana ou um desequilíbrio bacteriano, para a prevenção de uma doença associada a uma infecção bacteriana e para o tratamento de uma ferida infectada com bactérias e composição - são descritas aqui composições compreendendo fibras encurtadas de poli-n-acetilglucosamina e/ou um derivado do mesmo ("nanofibras snag") e aplicações antibacterianas de tais composições. as nanofibras snag pode ser formuladas como composições para a prevenção e/ou o tratamento de infecções bacterianas e doenças associadas a tais infecções. também são descritos regimes empregando tais composições.
BR112012025844A 2010-04-15 2011-04-15 uso de nanofibras snag BR112012025844A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32465710P 2010-04-15 2010-04-15
PCT/US2011/032709 WO2011130646A1 (en) 2010-04-15 2011-04-15 Anti-bacterial applications of poly -n-acetylglucosamine nanofibers

Publications (1)

Publication Number Publication Date
BR112012025844A2 true BR112012025844A2 (pt) 2017-07-18

Family

ID=44799052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012025844A BR112012025844A2 (pt) 2010-04-15 2011-04-15 uso de nanofibras snag

Country Status (13)

Country Link
US (5) US8858964B2 (pt)
EP (1) EP2563371A4 (pt)
JP (3) JP2013523898A (pt)
KR (1) KR101883797B1 (pt)
CN (2) CN103108638B (pt)
AU (1) AU2011239466B2 (pt)
BR (1) BR112012025844A2 (pt)
CA (1) CA2796068C (pt)
HK (1) HK1185278A1 (pt)
IL (1) IL222375A (pt)
MX (1) MX342912B (pt)
NZ (2) NZ602909A (pt)
WO (1) WO2011130646A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3000487B8 (en) 2007-02-19 2022-06-15 Marine Polymer Technologies, Inc. Hemostatic compositions and therapeutic regimens
US8858964B2 (en) 2010-04-15 2014-10-14 Marine Polymer Technologies, Inc. Anti-bacterial applications of poly-N-acetylglucosamine nanofibers
NZ715595A (en) 2011-04-15 2017-06-30 Marine Polymer Tech Inc Treatment of disease with poly-n-acetyglucosamine nanofibers
US20140322722A1 (en) * 2011-09-30 2014-10-30 The Research Institute At Nationwide Children's Hospital Compositions and methods for detection of defensins in a patient sample
MX2014014067A (es) * 2012-05-22 2015-02-04 Novartis Ag Conjugado de serogrupo x de meningococo.
US20150237837A1 (en) * 2012-06-18 2015-08-27 Duke University Non-Human Model for Wound Healing
US10876161B2 (en) * 2012-12-20 2020-12-29 Hills Pet Nutrition, Inc. Pattern recognition receptor expression as a measure of systemic health
EP2968190B1 (en) * 2013-03-14 2018-10-17 Marine Polymer Technologies, Inc. Treatment of disease with poly-n-acetylglucosamine nanofibers
JP2015048436A (ja) * 2013-09-03 2015-03-16 公立大学法人福井県立大学 植物の耐病性を向上させる、生物由来キチン質含有物、その使用方法、及びその製造方法
EP3034612A1 (en) 2014-12-16 2016-06-22 Greenaltech, S.L. Chitin and chitosan producing methods
US10500222B2 (en) * 2015-10-19 2019-12-10 Wayne State University Compositions and methods relating to treatment of infection
CN107460140B (zh) * 2016-06-02 2020-11-13 浙江科技学院 一种芽孢杆菌hz16中抑制军团菌活性物的制备方法
WO2019046577A1 (en) * 2017-08-31 2019-03-07 Syngulon Sa METHODS AND COMPOSITIONS FOR THE PRODUCTION OF BACTERIOCIN AND ANTIMICROBIAL PEPTIDES
US20210169922A1 (en) * 2018-05-11 2021-06-10 Marine Polymer Technologies, Inc. Use of poly-n-acetylglucosamine nanofibers for the treatment of gingival recession
BR102021021376A2 (pt) * 2021-10-25 2023-05-09 União Brasileira De Educação Católica - Ubec Composição, processo de produção da composição e uso da composição de nanofibras que compreende pva, quitosana, antibiótico e peptídeo de defesa do hospedeiro
IT202200004574A1 (it) 2022-03-10 2023-09-10 Sergio Ammendola Nanoparticelle di N-acetilglucosammina e loro applicazioni
KR20230147412A (ko) * 2022-04-14 2023-10-23 충남대학교산학협력단 miRNA 24가 봉입된 키토산 나노입자를 유효성분으로 포함하는 에드워드시엘라 피스시시다에 대한 어류용 항생 조성물
CN115671368B (zh) * 2022-10-28 2024-03-22 东华大学 一种用于生物膜清除的纳米纤维复合贴片及其制备方法

Family Cites Families (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038367A (en) 1963-05-28 1966-08-10 Beecham Group Ltd Penicillin derivatives
US3989535A (en) 1974-02-11 1976-11-02 American Cyanamid Company Solution of poly(N-acetyl-D-glucosamine)
US3988411A (en) 1974-02-11 1976-10-26 American Cyanamid Company Spinning and shaping poly-(N-acetyl-D-glucosamine)
US4068757A (en) 1976-11-03 1978-01-17 American Cyanamid Company Chitin derived powder in sterile surgical element package
US4195175A (en) 1978-01-03 1980-03-25 Johnson Edwin L Process for the manufacture of chitosan
JPS55152705A (en) 1979-05-18 1980-11-28 Mitsubishi Rayon Co Ltd Preparation of water-soluble alkali chitin
JPS56133344A (en) 1980-03-21 1981-10-19 Kureha Chem Ind Co Ltd Novel composite material
JPS56131639A (en) 1980-03-21 1981-10-15 Kureha Chem Ind Co Ltd Protein-chitosan composition
US4378017A (en) 1980-03-21 1983-03-29 Kureha Kagaku Kogyo Kabushiki Kaisha Composite material of de-N-acetylated chitin and fibrous collagen
US4532134A (en) 1981-04-06 1985-07-30 Malette William Graham Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound
US4394373A (en) 1981-04-06 1983-07-19 Malette William Graham Method of achieving hemostasis
US4470397A (en) 1981-11-11 1984-09-11 Lucas Industries Public Limited Company Fuel injection pumping apparatus
US4605623A (en) 1982-11-08 1986-08-12 Malette William Graham Method of altering growth and development and suppressing contamination microorganisms in cell or tissue culture
JPS5998660A (ja) 1982-11-26 1984-06-07 House Food Ind Co Ltd 麺類の乾燥方法
JPS59156770A (ja) 1983-02-25 1984-09-06 Canon Inc インパクト型プリンタ
JPS58220899A (ja) 1983-03-22 1983-12-22 工業技術院長 キチン系抄造体の製造方法
JPS6025003A (ja) 1983-07-20 1985-02-07 Shiro Okamura 光磁気記録装置
US4803168A (en) 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
US4749620A (en) 1984-02-15 1988-06-07 Massachusetts Institute Of Technology Encapsulated active material system
JPS60208302A (ja) 1984-03-31 1985-10-19 Unitika Ltd キチン成形体の製造方法
JPS60215003A (ja) 1984-04-10 1985-10-28 Unitika Ltd キトサン成形体の製造方法
DE3583263D1 (de) 1984-08-03 1991-07-25 Unitika Ltd Geformte gegenstaende aus chitin.
JPH0611810B2 (ja) 1984-08-23 1994-02-16 ユニチカ株式会社 多孔性キチン成形体及びその製造方法
JPS61253065A (ja) 1985-05-02 1986-11-10 片倉チツカリン株式会社 キトサン誘導体およびコラ−ゲンの複合材の医用材料およびその製造法
US4895724A (en) 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
JPS62288602A (ja) 1986-06-06 1987-12-15 Agency Of Ind Science & Technol キトサン変性物粒子の製造方法
JPH0776241B2 (ja) 1986-06-06 1995-08-16 ユニオン、カーバイド、コーポレーション アミノ多糖類及びそれらの誘導体の酸による非晶出化方法
JPH0441422Y2 (pt) 1986-10-17 1992-09-29
JPH0525289Y2 (pt) 1987-01-21 1993-06-25
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4942129A (en) 1987-07-28 1990-07-17 Queen's University At Kingston Multiple membrane microencapsulation
US5571821A (en) 1993-05-20 1996-11-05 Texas Biotechnology Corporation Sulfonamides and derivatives thereof that modulate the activity of endothelin
JPH0532702Y2 (pt) 1987-10-09 1993-08-20
JP2560363B2 (ja) 1987-12-23 1996-12-04 ライオン株式会社 キチン又はキトサン類の精製法
EP0330106A1 (de) 1988-02-25 1989-08-30 Akzo Nobel N.V. Modifizierte Cellulose für biocompatible Dialysemembranen II und Verfahren zu deren Herstellung
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5008116A (en) 1988-11-14 1991-04-16 Frederick Cahn Immunostimulatory microsphere
DE3903797A1 (de) 1989-02-09 1990-08-16 Hoechst Ag Verfahren zur herstellung von aktivierten chitosanen und deren verwendung bei der herstellung von chitosanderivaten
JPH0657761B2 (ja) 1989-02-27 1994-08-03 富士紡績株式会社 多孔質キトサン成形物の製造法
JPH02240101A (ja) 1989-03-14 1990-09-25 Lion Corp 硫酸化キトサン誘導体及びその製造方法
EP0390481B1 (en) 1989-03-23 1996-02-28 Sanyo Chemical Industries Ltd. Surgical adhesive sheet
IT1229167B (it) 1989-04-10 1991-07-22 Texcontor Ets Complessi del ferro o di altri metalli con derivati solfonati del chitosano
US5071977A (en) 1989-05-10 1991-12-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Plaque inhibiting oligosaccharide
AU5885690A (en) 1989-07-11 1991-01-17 Union Carbide Chemicals And Plastics Company Inc. Emulsions comprising aminopolysaccharides
US5116747A (en) 1989-08-11 1992-05-26 University Of Waterloo Immobilization of biologically active material in capsules prepared from a water-soluble polymer and chitosan acetate
US5093319A (en) 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
IL96101A0 (en) 1989-10-31 1991-07-18 Pfizer Hospital Prod Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
JPH064531B2 (ja) 1990-06-04 1994-01-19 アイセロ化学株式会社 大腸崩壊性硬質カプセル
DK0544000T3 (da) 1990-08-17 1997-11-03 Drug Delivery System Inst Ltd N-acetylcarboxymethylchitosanderivater og fremgangsmåde til fremstilling deraf.
ES2103003T3 (es) 1990-08-30 1997-08-16 Warner Lambert Co Articulos formados de una fusion de almidon termoplastica.
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
JPH04126701U (ja) 1991-05-13 1992-11-18 株式会社日立製作所 潤滑機能を有する下部軸受
US5382569A (en) 1991-05-16 1995-01-17 Warner-Lambert Company Endotherlin antagonists
JPH0691819B2 (ja) 1991-05-27 1994-11-16 工業技術院長 デアセチラーゼの製造方法
JP3046099B2 (ja) 1991-06-19 2000-05-29 ユニチカ株式会社 キチン又はキトサンの綿状物
CA2072395A1 (en) 1991-07-01 1993-01-02 John T. Hunt Bicyclic endothelin analogues
JPH0525289A (ja) 1991-07-19 1993-02-02 Unitika Ltd キチン成形体の製造法
JPH0532702A (ja) 1991-08-01 1993-02-09 Unitika Ltd 細胞接着性キチン
JPH0551465A (ja) 1991-08-23 1993-03-02 Unitika Ltd 球状キチンの製造方法
US5229123A (en) 1991-10-09 1993-07-20 Hoffmann-La Roche Inc. Antifungal agents
US5219749A (en) 1991-10-09 1993-06-15 Institute For Molecular Biology & Biotechnology/Forth Process for isolating and preparing purified chitin deacetylase
EP0610441A4 (en) 1991-10-29 1996-01-10 Clover Cons Ltd CROSSLINKABLE POLYSACCHARIDES, POLYCATIONS AND LIPIDS CAN BE USED TO ENCODE AND DISPENSE MEDICINAL PRODUCTS.
HUT67665A (en) 1991-11-05 1995-04-28 Smithkline Beckman Corp Indane and indene deriv.s as endothelin receptor antagonists, pharmaceutical compn.s contg. them and process for prepg. them
IL100096A (en) 1991-11-20 1996-03-31 Univ Ramot Method for entrapment of active materials in chitosan
US5260002A (en) 1991-12-23 1993-11-09 Vanderbilt University Method and apparatus for producing uniform polymeric spheres
DE4200080A1 (de) 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
JPH05235905A (ja) 1992-02-21 1993-09-10 Toshiba Corp Crc演算装置
JPH076126A (ja) 1992-02-26 1995-01-10 Nec Corp プロセッサ間バス伝送方式
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
JPH05271094A (ja) 1992-03-26 1993-10-19 Fuji Photo Film Co Ltd カルボキシメチル化キチン誘導体を用いる癌転移抑制剤
US5550110A (en) 1992-04-22 1996-08-27 Warner-Lambert Company Endothelin Antagonists II
WO1994003483A1 (en) 1992-07-30 1994-02-17 Chiron Corporation Endothelin receptor-binding compounds
US5871985A (en) 1992-09-28 1999-02-16 Brown University Research Foundation Particulate non cross-linked chitosan core matrices for encapsulated cells
TW394761B (en) 1993-06-28 2000-06-21 Hoffmann La Roche Novel Sulfonylamino Pyrimidines
US5447505A (en) 1993-08-04 1995-09-05 Merocel Corporation Wound treatment method
JPH07102458A (ja) 1993-09-30 1995-04-18 Unitika Ltd キチンウェブ状物
US5622834A (en) 1993-12-01 1997-04-22 Marine Polymer Technologies, Inc. Method of isolating poly-β-1-4-N-acetylglucosamine from microalgal culture
US6063911A (en) 1993-12-01 2000-05-16 Marine Polymer Technologies, Inc. Methods and compositions for treatment of cell proliferative disorders
US5846952A (en) 1993-12-01 1998-12-08 Marine Polymer Technologies, Inc. Methods and compositions for poly-β-1-4-N-acetylglucosamine drug delivery
US5686115A (en) 1993-12-01 1997-11-11 Marine Polymer Technologies, Inc. Poly-β-1→4-N-acetylucosamine copolymer composition with collagen
US5635493A (en) 1993-12-01 1997-06-03 Marine Polymer Technologies, Inc. Methods and compositions for poly-β-1-4-N-acetylglucosamine chemotherapeutics
US6743783B1 (en) 1993-12-01 2004-06-01 Marine Polymer Technologies, Inc. Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine
US5858350A (en) 1993-12-01 1999-01-12 Marine Polymer Technologies Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system
US5624679A (en) 1993-12-01 1997-04-29 Marine Polymer Technologies, Inc. Methods and compositions for poly-β-1-4-N-acetylglucosamine biological barriers
US5811416A (en) 1994-06-06 1998-09-22 Board Of Regents The University Of Texas System Endothelin antagonist and/or endothelin synthase inhibitor in combination with a progestin, an estrogen, a cyclooxygenase inhibitor, or a nitric acid donor or substrate
WO1996011927A1 (en) 1994-10-12 1996-04-25 Abbott Laboratories Endothelin antagonists
TW313568B (pt) 1994-12-20 1997-08-21 Hoffmann La Roche
US5658943A (en) 1995-01-05 1997-08-19 Warner-Lambert Company Phenylalanine derivatives as endothelin antagonists
US5510102A (en) 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
AU5917896A (en) 1995-06-06 1996-12-24 Marine Polymer Technologies, Inc. Poly-beta-1-4-N-acetylglucosamine
FR2736835B1 (fr) 1995-07-17 1997-10-10 Aber Technologies Pansement pour plaies chroniques, notamment escarres, en gel de chitine
WO1997008169A1 (en) 1995-08-24 1997-03-06 Warner-Lambert Company Furanone endothelin antagonists
US6043241A (en) 1996-04-10 2000-03-28 Warner-Lambert Company Ketoacid endothelin antagonists
US5804594A (en) 1997-01-22 1998-09-08 Murad; Howard Pharmaceutical compositions and methods for improving wrinkles and other skin conditions
WO1998033781A1 (en) 1997-01-30 1998-08-06 Bristol-Myers Squibb Company Method for preventing or treating low renin hypertension by administering an endothelin antagonist
US20030060434A1 (en) 1997-02-18 2003-03-27 Loretta Nielsen Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms
US6162241A (en) 1997-08-06 2000-12-19 Focal, Inc. Hemostatic tissue sealants
ES2221696T3 (es) 1997-08-19 2005-01-01 F. Hoffmann-La Roche Ag Procedimiento para la preparacion de piridinas 2,5.disustituidas.
CA2234936C (en) 1998-04-17 2004-06-29 Glucogenics Pharmaceuticals Inc. Composition for and treatment of inflammatory bowel disease by colon administration of n-acetylglucosamine
US6046179A (en) 1998-04-17 2000-04-04 Murch; Simon Composition for and treatment of inflammatory bowel disease by colon administration of N-acetylglucosamine
DE19821598A1 (de) 1998-05-14 1999-11-18 Henkel Kgaa Verfahren zum Abbau von Biopolymeren
TW585762B (en) 1999-11-11 2004-05-01 Tanabe Seiyaku Co Pharmaceutical composition for prophylaxis or treatment of inflammatory bowel diseases
US7041657B2 (en) 2001-02-12 2006-05-09 Marine Polymer Technologies Inc. Compositions and methods for modulation of vascular structure and/or function
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
US7371403B2 (en) 2002-06-14 2008-05-13 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
JP2003128704A (ja) 2001-10-24 2003-05-08 Matsumoto Shika Univ キチン・キトサンの低分子化方法及び骨伝導物の製造方法
GB0126923D0 (en) 2001-11-09 2002-01-02 Procter & Gamble Chitosan compositions
US20030144347A1 (en) 2001-11-14 2003-07-31 Ralph Ryback Method for treating autoimmune disease
JP3947391B2 (ja) 2001-11-28 2007-07-18 独立行政法人 日本原子力研究開発機構 橋かけ構造を有するキチン誘導体及び/又はキトサン誘導体の製造方法
US20090130186A1 (en) * 2002-06-14 2009-05-21 Hemcon Medical Technologies, Inc. Wound dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan and incorporating silver nanoparticles
US7037983B2 (en) 2002-06-14 2006-05-02 Kimberly-Clark Worldwide, Inc. Methods of making functional biodegradable polymers
FR2843125B1 (fr) 2002-08-02 2012-11-16 Coletica Principes actifs stimulant les beta-defensives humaines de type 2 et/ou de type 3, et compositions cosmetiques ou pharmaceutiques comprenant de tels principes actifs
WO2004024196A1 (en) 2002-09-11 2004-03-25 Johnson & Johnson Medical Limited Wound dressings for the treatment of wound infection
GB2393120A (en) 2002-09-18 2004-03-24 Johnson & Johnson Medical Ltd Compositions for wound treatment
US20070237812A1 (en) 2006-04-11 2007-10-11 Tyco Healthcare Group Multi-layer wound dressings
EP1587424A4 (en) 2002-12-31 2012-01-25 Marinepolymer Tech Inc Bleeding Compounds and their uses
WO2004076637A2 (en) 2003-02-24 2004-09-10 Marine Polymer Technologies, Inc. Cell-polymer fiber compositions and use thereof
NZ546204A (en) 2003-09-12 2009-12-24 Marinepolymer Tech Inc Vascular access preservation in haemodialysis patients
BRPI0414543A (pt) 2003-09-19 2006-11-07 Otsuka Pharma Co Ltd promotor de secreção de beta-defensina humana
RU2240830C1 (ru) 2003-12-26 2004-11-27 ФГУП Государственный научно-исследовательский институт особо чистых биопрепаратов Раневое покрытие и способ его получения
EP1722630A4 (en) 2004-01-20 2009-05-27 Richard F Harty COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASES
US7780873B2 (en) 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
JP2005281239A (ja) 2004-03-30 2005-10-13 Nippon Zeon Co Ltd 鶏用dnaワクチン
US7704522B2 (en) 2004-09-08 2010-04-27 Clyde Morgan Topical medicament
US20060105049A1 (en) 2004-11-12 2006-05-18 Valorisation Recherche Hscm & Universite De Montreal Folic acid-chitosan-DNA nanoparticles
DE102004061406A1 (de) 2004-12-21 2006-07-06 Bayer Innovation Gmbh Infektionsresistente Polyurethanschäume, Verfahren zu ihrer Herstellung und Verwendung in antiseptisch ausgestatteten Wundauflagen
US20070036846A1 (en) * 2005-08-15 2007-02-15 Tsang Wing W M Wound dressing and method of manufacture thereof
WO2007059605A1 (en) 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
US8277849B2 (en) 2006-01-19 2012-10-02 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
ES2536426T3 (es) 2006-03-23 2015-05-25 Novartis Ag Compuestos de imidazoquinoxalina como inmunomoduladores
WO2007109812A2 (en) 2006-03-23 2007-09-27 Novartis Ag Immunopotentiating compounds
EP2068917A2 (en) 2006-09-22 2009-06-17 Government of the USA, as Represented by the Secretary, Department of Health and Human Services Compositions and methods for chitosan enhanced immune response
JP2010506908A (ja) 2006-10-20 2010-03-04 スーヨル キム, グルコサミンまたはグルコサミン誘導体を含むアトピー性皮膚炎治療用組成物およびこれらを使用しアトピー性皮膚炎を治療する方法
KR100882611B1 (ko) 2006-11-14 2009-02-12 주식회사 키토라이프 표적 리간드로서 폴릭산이 도입된 유전자 전달체용저분자량 수용성 키토산 나노입자 및 이의 제조방법
JP5541926B2 (ja) 2007-01-31 2014-07-09 アラーガン、インコーポレイテッド 眼薬物送達用の新規生体材料ならびにその製造および使用方法
EP3000487B8 (en) * 2007-02-19 2022-06-15 Marine Polymer Technologies, Inc. Hemostatic compositions and therapeutic regimens
ES2324192B1 (es) * 2008-01-30 2010-06-17 PUIG BEAUTY & FASHION GROUP, S.L. Derivados peptidicos utiles en el tratamiento, cuidado o limpieza de la piel, mucosa, cuero cabelludo o uñas.
US8436157B2 (en) 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
JP2011528332A (ja) 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物ベータ・デフェンシンを用いた炎症性疾患の処置
US20100086613A1 (en) 2008-10-03 2010-04-08 Chang-Jer Wu Chitosan vehicle and method for making same
US20100105139A1 (en) 2008-10-27 2010-04-29 Remco Alexander Spanjaard Ligand Targeted Nanocapsules for the delivery of RNAi and other Agents
US8858964B2 (en) 2010-04-15 2014-10-14 Marine Polymer Technologies, Inc. Anti-bacterial applications of poly-N-acetylglucosamine nanofibers
US20130210717A1 (en) 2010-05-10 2013-08-15 Corporation De L'ecole Polytechnique De Montreal Gene therapy for diabetes with chitosan-delivered plasmid encoding glucagon-like peptide 1
ES2763432T3 (es) 2010-11-06 2020-05-28 Marine Polymer Tech Inc Composiciones y métodos para la administración de ácidos nucleicos a base de nanopolímeros
NZ715595A (en) 2011-04-15 2017-06-30 Marine Polymer Tech Inc Treatment of disease with poly-n-acetyglucosamine nanofibers
JP5496427B2 (ja) 2011-09-15 2014-05-21 国立大学法人鳥取大学 炎症性腸疾患治療剤
EP2968190B1 (en) 2013-03-14 2018-10-17 Marine Polymer Technologies, Inc. Treatment of disease with poly-n-acetylglucosamine nanofibers

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