BR112012015386B8 - composição oftálmica tópica - Google Patents

composição oftálmica tópica

Info

Publication number
BR112012015386B8
BR112012015386B8 BR112012015386A BR112012015386A BR112012015386B8 BR 112012015386 B8 BR112012015386 B8 BR 112012015386B8 BR 112012015386 A BR112012015386 A BR 112012015386A BR 112012015386 A BR112012015386 A BR 112012015386A BR 112012015386 B8 BR112012015386 B8 BR 112012015386B8
Authority
BR
Brazil
Prior art keywords
ophthalmic composition
topical ophthalmic
ocular diseases
topical
prevention
Prior art date
Application number
BR112012015386A
Other languages
English (en)
Other versions
BR112012015386A2 (pt
BR112012015386B1 (pt
Inventor
Ponsati Obiols Berta
HERNÁNDEZ PASCUAL Cristina
FERNÁNDEZ CARNEADO Jimena
Farrera Sinfreu Josep
GÓMEZ CAMINALS Marc
SIMÓ CANONGE Rafael
Jordana I Lluch Ribera
Original Assignee
Bcn Peptides Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43928893&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012015386(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bcn Peptides Sa filed Critical Bcn Peptides Sa
Publication of BR112012015386A2 publication Critical patent/BR112012015386A2/pt
Publication of BR112012015386B1 publication Critical patent/BR112012015386B1/pt
Publication of BR112012015386B8 publication Critical patent/BR112012015386B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composição oftálmica tópica. trata-se de uma formulação oftálmica de peptídeos e seu uso para o tratamento e/ou prevenção local de doenças oculares, de preferência, doenças oculares do segmento posterior.
BR112012015386A 2009-12-22 2010-12-17 composição oftálmica tópica BR112012015386B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200931242A ES2362604B1 (es) 2009-12-22 2009-12-22 Formulación tópica oftálmica de péptidos.
ESP200931242 2009-12-23
PCT/EP2010/007737 WO2011076368A2 (en) 2009-12-22 2010-12-17 Topical ophthalmic peptide formulation

Publications (3)

Publication Number Publication Date
BR112012015386A2 BR112012015386A2 (pt) 2018-07-24
BR112012015386B1 BR112012015386B1 (pt) 2021-02-23
BR112012015386B8 true BR112012015386B8 (pt) 2021-05-25

Family

ID=43928893

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012015386A BR112012015386B8 (pt) 2009-12-22 2010-12-17 composição oftálmica tópica

Country Status (34)

Country Link
US (1) US9216208B2 (pt)
EP (1) EP2515870B1 (pt)
JP (1) JP5920928B2 (pt)
KR (1) KR101657737B1 (pt)
CN (1) CN102753153B (pt)
AR (1) AR079683A1 (pt)
AU (1) AU2010335595B2 (pt)
BR (1) BR112012015386B8 (pt)
CA (1) CA2785104C (pt)
CL (1) CL2012001737A1 (pt)
CO (1) CO6592047A2 (pt)
CY (1) CY1117854T1 (pt)
DK (1) DK2515870T3 (pt)
ES (2) ES2362604B1 (pt)
HK (1) HK1178049A1 (pt)
HR (1) HRP20160954T1 (pt)
HU (1) HUE028193T2 (pt)
IL (1) IL220584A (pt)
LT (1) LT2515870T (pt)
MX (1) MX338323B (pt)
MY (1) MY178169A (pt)
NZ (1) NZ600627A (pt)
PL (1) PL2515870T3 (pt)
PT (1) PT2515870T (pt)
RS (1) RS54953B1 (pt)
RU (1) RU2561585C2 (pt)
SG (1) SG181727A1 (pt)
SI (1) SI2515870T1 (pt)
SM (1) SMT201600277B (pt)
TW (1) TWI548416B (pt)
UA (1) UA108484C2 (pt)
UY (1) UY33153A (pt)
WO (1) WO2011076368A2 (pt)
ZA (1) ZA201204522B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9707273B2 (en) 2013-03-01 2017-07-18 Fundació Hospital Universitari Vall D'hebron—Institut De Recerca Peptides for use in the topical treatment of retinal neurodegenerative diseases, in particular in early stages of diabetic retinopathy and other retinal diseases in which neurodegeneration plays an essential role
GB201516066D0 (en) * 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
CN106822182A (zh) * 2016-12-27 2017-06-13 广州姿生生物科技有限公司 一种细胞提取物及其用途
RU2729079C1 (ru) 2017-01-31 2020-08-04 Кимберли-Кларк Ворлдвайд, Инк. Антибактериальная композиция, содержащая сложный эфир бензойной кислоты, и способы подавления бактериального роста посредством ее применения
US20180325993A1 (en) 2017-05-15 2018-11-15 Sun Pharmaceutical Industries Limited Octreotide injection
EP4052694A4 (en) * 2019-11-21 2023-09-20 Samjin Pharmaceutical Co., Ltd. EYE DROPS COMPOSITION FOR PREVENTING OR TREATING EYE DISEASES
KR20230133595A (ko) * 2022-03-11 2023-09-19 한국한의약진흥원 등검은말벌독에 함유된 세로토닌의 안정성을 유지하기 위한 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182258A (en) 1989-03-20 1993-01-26 Orbon Corporation Systemic delivery of polypeptides through the eye
AU1307399A (en) * 1997-11-06 1999-05-31 Orbon Corporation Stabilized, dry pharmaceutical compositions for drug delivery and methods of preparing same
CA2263042A1 (en) * 1999-02-25 2000-08-25 Robert W.A. Kuijpers Treatment of edema
EP1040837A3 (en) * 1999-02-26 2002-01-02 Erasmus Universiteit Rotterdam Medicaments for the treatment of a choroidal neovascularization (CNV) related disorder
AU2001283957A1 (en) 2000-07-27 2002-02-13 Novartis Ag Treatment of ocular disorders with somatostatin analogues
TWI260228B (en) 2002-12-31 2006-08-21 Ind Tech Res Inst Delivery carrier of presenting cell of somatostatin receptor
US20050074497A1 (en) 2003-04-09 2005-04-07 Schultz Clyde L. Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US8871269B2 (en) 2003-07-15 2014-10-28 Evonik Corporation Method for the preparation of controlled release formulations
US20070082841A1 (en) * 2005-09-27 2007-04-12 Aciont, Inc. Ocular administration of immunosuppressive agents
US20100216724A1 (en) * 2007-09-11 2010-08-26 Dorian Bevec Use of fibronectin fragment (196-203 ) as a therapeutic agent
EP2886105B1 (en) * 2007-10-24 2018-12-05 Camurus Ab Controlled-release formulations

Also Published As

Publication number Publication date
MX2012007282A (es) 2012-10-15
RU2561585C2 (ru) 2015-08-27
SG181727A1 (en) 2012-07-30
ES2362604B1 (es) 2012-06-28
IL220584A0 (en) 2012-08-30
DK2515870T3 (en) 2016-09-05
PT2515870T (pt) 2016-08-29
UY33153A (es) 2011-06-30
KR20120120255A (ko) 2012-11-01
ES2587828T3 (es) 2016-10-27
IL220584A (en) 2016-10-31
ZA201204522B (en) 2013-09-25
TWI548416B (zh) 2016-09-11
AU2010335595B2 (en) 2015-08-27
WO2011076368A3 (en) 2012-03-15
CO6592047A2 (es) 2013-01-02
CL2012001737A1 (es) 2012-11-16
BR112012015386A2 (pt) 2018-07-24
HK1178049A1 (zh) 2013-09-06
MY178169A (en) 2020-10-06
LT2515870T (lt) 2016-10-10
RS54953B1 (sr) 2016-11-30
KR101657737B1 (ko) 2016-09-19
HRP20160954T1 (hr) 2016-10-07
CA2785104A1 (en) 2011-06-30
ES2362604A1 (es) 2011-07-08
AR079683A1 (es) 2012-02-15
TW201141514A (en) 2011-12-01
EP2515870B1 (en) 2016-05-25
CY1117854T1 (el) 2017-05-17
CA2785104C (en) 2016-11-01
CN102753153B (zh) 2015-11-25
EP2515870A2 (en) 2012-10-31
RU2012126028A (ru) 2014-01-27
JP5920928B2 (ja) 2016-05-18
MX338323B (es) 2016-04-12
SI2515870T1 (sl) 2016-09-30
CN102753153A (zh) 2012-10-24
AU2010335595A1 (en) 2012-07-12
US20130210728A1 (en) 2013-08-15
WO2011076368A2 (en) 2011-06-30
HUE028193T2 (en) 2016-12-28
PL2515870T3 (pl) 2016-11-30
UA108484C2 (en) 2015-05-12
BR112012015386B1 (pt) 2021-02-23
JP2013515687A (ja) 2013-05-09
US9216208B2 (en) 2015-12-22
NZ600627A (en) 2014-08-29
SMT201600277B (it) 2016-11-10

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/02/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/12/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF