BR112012014164A2 - inibidores da esfingosina quinase - Google Patents

inibidores da esfingosina quinase

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Publication number
BR112012014164A2
BR112012014164A2 BR112012014164A BR112012014164A BR112012014164A2 BR 112012014164 A2 BR112012014164 A2 BR 112012014164A2 BR 112012014164 A BR112012014164 A BR 112012014164A BR 112012014164 A BR112012014164 A BR 112012014164A BR 112012014164 A2 BR112012014164 A2 BR 112012014164A2
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BR
Brazil
Prior art keywords
kinase inhibitors
sphingosine kinase
formulaq
tautomers
prodrugs
Prior art date
Application number
BR112012014164A
Other languages
English (en)
Inventor
Dirk Wienke
Frank Stieber
Original Assignee
Merck Patent Gmbh
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Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR112012014164A2 publication Critical patent/BR112012014164A2/pt

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    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Abstract

inibidores da esfingosina quinase a presente invenção refere-se a compostos da fórmulaq (i) em que r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, r11,r12, r13, r14, r15, r16, r17, m1, m2, m3, m4, y1, y2, v, w, n, m e o possuem os significados indicados na reivindicação 1, e sais fisiologicamente aceitáveis, derivados, pró-fármacos, solvatos, tautômeros e estereoisômeros desses, incluindo as suas misturas em todas as razões, para o uso no tratamento de doenças que são influenciadas pela inibição de sph quinase 1.
BR112012014164A 2009-12-14 2010-11-22 inibidores da esfingosina quinase BR112012014164A2 (pt)

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IL220187A0 (en) 2012-07-31
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