BR0313792A - Utilização de proteìna de eritropoetina, método para tratamento de distúrbios de distribuição de ferro em diabetes e medicamento para o seu tratamento - Google Patents
Utilização de proteìna de eritropoetina, método para tratamento de distúrbios de distribuição de ferro em diabetes e medicamento para o seu tratamentoInfo
- Publication number
- BR0313792A BR0313792A BR0313792-9A BR0313792A BR0313792A BR 0313792 A BR0313792 A BR 0313792A BR 0313792 A BR0313792 A BR 0313792A BR 0313792 A BR0313792 A BR 0313792A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- diabetes
- medicine
- iron distribution
- erythropoietin protein
- Prior art date
Links
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title abstract 6
- 229910052742 iron Inorganic materials 0.000 title abstract 3
- 102000003951 Erythropoietin Human genes 0.000 title abstract 2
- 108090000394 Erythropoietin Proteins 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 abstract 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
"UTILIZAçãO DE PROTEìNA DE ERITROPOETINA, MéTODO PARA TRATAMENTO DE DISTúRBIOS DE DISTRIBUIçãO DE FERRO EM DIABETES E MEDICAMENTO PARA O SEU TRATAMENTO". A presente invenção refere-se ao uso de eritropoetina para o tratamento de distúrbios de distribuição de ferro em diabetes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02019100 | 2002-08-29 | ||
PCT/EP2003/009194 WO2004019972A1 (en) | 2002-08-29 | 2003-08-20 | Use of erythopoietin |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0313792A true BR0313792A (pt) | 2005-07-12 |
BRPI0313792B1 BRPI0313792B1 (pt) | 2016-10-18 |
BRPI0313792B8 BRPI0313792B8 (pt) | 2021-05-25 |
Family
ID=31970265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0313792A BRPI0313792B8 (pt) | 2002-08-29 | 2003-08-20 | utilização de proteína de eritropoetina, método para tratamento de distúrbios de distribuição de ferro em diabetes e medicamento para o seu tratamento |
Country Status (15)
Country | Link |
---|---|
US (1) | US7459435B2 (pt) |
EP (1) | EP1536823B1 (pt) |
JP (1) | JP5128048B2 (pt) |
KR (1) | KR20050057054A (pt) |
CN (1) | CN1311866C (pt) |
AR (1) | AR041061A1 (pt) |
AT (1) | ATE510556T1 (pt) |
AU (1) | AU2003251713B2 (pt) |
BR (1) | BRPI0313792B8 (pt) |
CA (1) | CA2496581C (pt) |
ES (1) | ES2364651T3 (pt) |
MX (1) | MXPA05002067A (pt) |
PL (1) | PL209699B1 (pt) |
RU (1) | RU2305554C2 (pt) |
WO (1) | WO2004019972A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1901934B (zh) * | 2003-12-19 | 2013-09-11 | 弗·哈夫曼-拉罗切有限公司 | ***在治疗慢性炎症性肠病中铁分布紊乱中的用途 |
KR101100059B1 (ko) * | 2004-06-30 | 2011-12-29 | 넥타르 테라퓨틱스 | 중합체인자 ix 부분의 접합체 |
WO2006061853A2 (en) * | 2004-12-10 | 2006-06-15 | Serum Institute Of India Limited | Novel erythropoietic compounds and a process for producing erythropoietic compounds |
US8759292B2 (en) | 2006-02-03 | 2014-06-24 | Prolor Biotech, Llc | Long-acting coagulation factors and methods of producing same |
US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
US7553940B2 (en) | 2006-02-03 | 2009-06-30 | Modigene Inc | Long-acting EPO polypeptides and derivatives thereof and methods thereof |
US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
US8450269B2 (en) | 2006-02-03 | 2013-05-28 | Prolor Biotech Ltd. | Long-acting growth hormone and methods of producing same |
US8476234B2 (en) * | 2006-02-03 | 2013-07-02 | Prolor Biotech Inc. | Long-acting coagulation factors and methods of producing same |
US8304386B2 (en) * | 2006-02-03 | 2012-11-06 | Prolor Biotech, Inc. | Long-acting growth hormone and methods of producing same |
US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
US8048848B2 (en) | 2006-02-03 | 2011-11-01 | Prolor Biotech Ltd. | Long-acting interferons and derivatives thereof and methods thereof |
WO2007108505A1 (ja) * | 2006-03-22 | 2007-09-27 | Chugai Seiyaku Kabushiki Kaisha | エリスロポエチン溶液製剤 |
US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
BR112014025951A2 (pt) | 2012-04-19 | 2017-07-11 | Opko Biologics Ltd | variantes de oxintomodulina de longa ação e métodos de produção do mesmo |
BR112015011583B1 (pt) | 2012-11-20 | 2023-03-14 | Opko Biologics Ltd | Métodos para aumentar o tamanho ou volume hidrodinâmico de hormônio de crescimento humano, método para aumentar o peso molecular aparente de um polipeptídeo e método para aumentar a meia-vida de um polipeptídeo |
US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
IL301728A (en) | 2015-06-19 | 2023-05-01 | Opko Biologics Ltd | Long-term coagulation factors and methods for their preparation |
CA3030533A1 (en) | 2016-07-11 | 2018-01-18 | Oren HERSHKOVITZ | Long-acting coagulation factor vii and methods of producing same |
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US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin |
US4745099A (en) * | 1985-02-06 | 1988-05-17 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of malignant tumors |
JP2858752B2 (ja) * | 1987-04-10 | 1999-02-17 | オーソ・フアーマシユーチカル・コーポレーシヨン | 正常な哺乳動物のヘマトクリツト値の増大方法 |
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US5733761A (en) * | 1991-11-05 | 1998-03-31 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
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-
2003
- 2003-08-04 US US10/634,477 patent/US7459435B2/en not_active Expired - Lifetime
- 2003-08-20 JP JP2004532098A patent/JP5128048B2/ja not_active Expired - Lifetime
- 2003-08-20 PL PL375784A patent/PL209699B1/pl unknown
- 2003-08-20 WO PCT/EP2003/009194 patent/WO2004019972A1/en active Search and Examination
- 2003-08-20 RU RU2005108976/15A patent/RU2305554C2/ru active
- 2003-08-20 CN CNB038205459A patent/CN1311866C/zh not_active Expired - Lifetime
- 2003-08-20 AT AT03790911T patent/ATE510556T1/de active
- 2003-08-20 CA CA2496581A patent/CA2496581C/en not_active Expired - Lifetime
- 2003-08-20 MX MXPA05002067A patent/MXPA05002067A/es active IP Right Grant
- 2003-08-20 EP EP03790911A patent/EP1536823B1/en not_active Expired - Lifetime
- 2003-08-20 KR KR1020057003501A patent/KR20050057054A/ko active Search and Examination
- 2003-08-20 AU AU2003251713A patent/AU2003251713B2/en not_active Expired
- 2003-08-20 ES ES03790911T patent/ES2364651T3/es not_active Expired - Lifetime
- 2003-08-20 BR BRPI0313792A patent/BRPI0313792B8/pt not_active IP Right Cessation
- 2003-08-27 AR ARP030103092A patent/AR041061A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1311866C (zh) | 2007-04-25 |
ATE510556T1 (de) | 2011-06-15 |
AU2003251713B2 (en) | 2006-12-21 |
JP2006503821A (ja) | 2006-02-02 |
EP1536823A1 (en) | 2005-06-08 |
CA2496581C (en) | 2019-09-03 |
MXPA05002067A (es) | 2005-06-08 |
CN1678341A (zh) | 2005-10-05 |
RU2305554C2 (ru) | 2007-09-10 |
AR041061A1 (es) | 2005-04-27 |
AU2003251713A1 (en) | 2004-03-19 |
RU2005108976A (ru) | 2006-01-27 |
US7459435B2 (en) | 2008-12-02 |
PL375784A1 (en) | 2005-12-12 |
EP1536823B1 (en) | 2011-05-25 |
CA2496581A1 (en) | 2004-03-11 |
WO2004019972A1 (en) | 2004-03-11 |
BRPI0313792B8 (pt) | 2021-05-25 |
JP5128048B2 (ja) | 2013-01-23 |
KR20050057054A (ko) | 2005-06-16 |
ES2364651T3 (es) | 2011-09-08 |
US20040110679A1 (en) | 2004-06-10 |
PL209699B1 (pl) | 2011-10-31 |
BRPI0313792B1 (pt) | 2016-10-18 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/10/2016, OBSERVADAS AS CONDICOES LEGAIS. |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/08/2003 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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