BR0312273A - Composição imunogênica, vacina, método para a preparação da mesma, e, uso de uma composição imunogênica - Google Patents
Composição imunogênica, vacina, método para a preparação da mesma, e, uso de uma composição imunogênicaInfo
- Publication number
- BR0312273A BR0312273A BR0312273-5A BR0312273A BR0312273A BR 0312273 A BR0312273 A BR 0312273A BR 0312273 A BR0312273 A BR 0312273A BR 0312273 A BR0312273 A BR 0312273A
- Authority
- BR
- Brazil
- Prior art keywords
- immunogenic composition
- vaccine
- preparation
- composition
- vaccines
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
- A61K39/018—Babesia antigens, e.g. Theileria antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/012—Coccidia antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
"COMPOSIçãO IMUNOGêNICA, VACINA, MéTODO PARA A PREPARAçãO DA MESMA, E, USO DE UMA COMPOSIçãO IMUNOGêNICA". A presente invenção proporciona uma composição imunogênica compreendendo uma proteína de fusão e um adjuvante saponina. A proteína de fusão compreende um peptídeo hidrofóbico heterólogo que está fundido na terminação N e/ou na terminação C de um polipeptídeo núcleo. O polipeptídeo núcleo compreende pelo menos um epitopo protetor. O adjuvante saponina nesta composição está presente em uma forma livre. Também são proporcionadas vacinas compreendendo a composição imunogênica e opcionalmente um componente imunorreativo adicional. Métodos para a preparação de tais vacinas, e uso da composição imunogênica para a manufatura de uma vacina também são proporcionados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02077800 | 2002-07-10 | ||
PCT/EP2003/007477 WO2004007525A2 (en) | 2002-07-10 | 2003-07-09 | Immunogenic composition comprising a fusion protein and a saponin adjuvant |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0312273A true BR0312273A (pt) | 2005-04-26 |
Family
ID=30011185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312273-5A BR0312273A (pt) | 2002-07-10 | 2003-07-09 | Composição imunogênica, vacina, método para a preparação da mesma, e, uso de uma composição imunogênica |
Country Status (8)
Country | Link |
---|---|
US (1) | US20060051365A1 (pt) |
EP (1) | EP1531858A2 (pt) |
JP (1) | JP2005532405A (pt) |
CN (1) | CN100421730C (pt) |
AU (1) | AU2003246674B2 (pt) |
BR (1) | BR0312273A (pt) |
CA (1) | CA2491704A1 (pt) |
WO (1) | WO2004007525A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140248273A1 (en) | 2001-09-08 | 2014-09-04 | Jos van Strijp | Vaccine based on staphylococcal superantigen-like 3 protein (ssl3) |
CA2738682A1 (en) * | 2004-04-15 | 2005-10-15 | Eng-Hong Lee | Soft gel delivery system for treating poultry |
EP2658568A1 (en) | 2010-12-29 | 2013-11-06 | Intervet International B.V. | Canine babesiosis vaccine antigen |
WO2015179840A1 (en) | 2014-05-23 | 2015-11-26 | Phibro Animal Health Corporation | Combination, composition, and method of administering the combination or composition to animals |
CN104845981B (zh) * | 2015-05-25 | 2018-06-19 | 中国疾病预防控制中心寄生虫病预防控制所 | 田鼠巴贝虫Bm1524抗原及其应用 |
CN104845982B (zh) * | 2015-05-25 | 2018-06-19 | 中国疾病预防控制中心寄生虫病预防控制所 | 田鼠巴贝虫Bm186抗原及其应用 |
CN110650750A (zh) * | 2017-04-04 | 2020-01-03 | 阿维迪科技公司 | 基于肽的疫苗、其制造方法及其用于诱导免疫应答的用途 |
WO2020056229A1 (en) * | 2018-09-14 | 2020-03-19 | Prommune, Inc. | Anti-parasitic immunological compositions |
CN109825514A (zh) * | 2019-01-24 | 2019-05-31 | 华中农业大学 | 田鼠巴贝斯虫gpi10基因及其编码的蛋白和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5109113A (en) * | 1986-05-02 | 1992-04-28 | Genentech, Inc. | Membrane anchor fusion polypeptides |
ZA872203B (en) * | 1986-04-28 | 1988-02-24 | New York Blood Center Inc | Complex immunogen containing synthetic peptides |
US6069230A (en) * | 1994-11-10 | 2000-05-30 | Promega Corporation | High level expression and facile purification of proteins, peptides and conjugates for immunization, purification and detection applications |
US5854051A (en) * | 1997-09-15 | 1998-12-29 | Heska Corporation | Parasitic helminth asparaginase proteins, nucleic acid molecules, and uses thereof |
DK1104306T3 (da) * | 1998-08-10 | 2006-05-22 | Antigenics Inc | Præparater af CpG- og saponinadjuvanser og fremgangsmåder til anvendelse deraf |
TW586935B (en) * | 1998-09-14 | 2004-05-11 | Kitasato Inst | Saponin-containing vaccine preparation |
GB0025577D0 (en) * | 2000-10-18 | 2000-12-06 | Smithkline Beecham Biolog | Vaccine |
-
2003
- 2003-07-09 WO PCT/EP2003/007477 patent/WO2004007525A2/en active Application Filing
- 2003-07-09 EP EP03763786A patent/EP1531858A2/en not_active Withdrawn
- 2003-07-09 CN CNB038160943A patent/CN100421730C/zh not_active Expired - Fee Related
- 2003-07-09 AU AU2003246674A patent/AU2003246674B2/en not_active Ceased
- 2003-07-09 BR BR0312273-5A patent/BR0312273A/pt not_active IP Right Cessation
- 2003-07-09 CA CA002491704A patent/CA2491704A1/en not_active Abandoned
- 2003-07-09 JP JP2004520565A patent/JP2005532405A/ja not_active Withdrawn
- 2003-09-07 US US10/520,698 patent/US20060051365A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1665530A (zh) | 2005-09-07 |
EP1531858A2 (en) | 2005-05-25 |
AU2003246674A1 (en) | 2004-02-02 |
CN100421730C (zh) | 2008-10-01 |
CA2491704A1 (en) | 2004-01-22 |
WO2004007525A2 (en) | 2004-01-22 |
JP2005532405A (ja) | 2005-10-27 |
WO2004007525A3 (en) | 2004-03-11 |
US20060051365A1 (en) | 2006-03-09 |
AU2003246674B2 (en) | 2008-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: INTERVET INTERNATIONAL B.V. (NL) Free format text: TRANSFERIDO DE: AKZO NOBEL N.V. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE 10A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2207 DE 24/04/2013. |