BR0311578A - seqüências de receptores cdr3 de células t e métodos para detecção - Google Patents

seqüências de receptores cdr3 de células t e métodos para detecção

Info

Publication number
BR0311578A
BR0311578A BRPI0311578-0A BR0311578A BR0311578A BR 0311578 A BR0311578 A BR 0311578A BR 0311578 A BR0311578 A BR 0311578A BR 0311578 A BR0311578 A BR 0311578A
Authority
BR
Brazil
Prior art keywords
methods
detection
receptor sequences
cell
disclosed
Prior art date
Application number
BRPI0311578-0A
Other languages
English (en)
Inventor
Jingwu Z Zhang
Original Assignee
Baylor College Medicine
Opexa Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine, Opexa Pharmaceuticals Inc filed Critical Baylor College Medicine
Publication of BR0311578A publication Critical patent/BR0311578A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)

Abstract

"SEQüêNCIAS DE RECEPTORES CDR3 DE CéLULAS T E MéTODOS PARA DETECçãO". A presente invenção refere-se geneticamente ao campo do tratamento de doenças auto-imunes, tais como MS (MS), artrite reumatóide (RA) e outras. Descreve-se métodos para tratar e monitorar uma doença auto-imune utilizando peptídeos receptores de células T. Descreve-se também seqüências de ácidos nucléicos e peptídeos de receptores de células T encontrados em uma população de pacientes com MS.
BRPI0311578-0A 2002-06-05 2003-06-05 seqüências de receptores cdr3 de células t e métodos para detecção BR0311578A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38628702P 2002-06-05 2002-06-05
PCT/US2003/017873 WO2003104407A2 (en) 2002-06-05 2003-06-05 T cell receptor cdr3 sequences and methods for detection

Publications (1)

Publication Number Publication Date
BR0311578A true BR0311578A (pt) 2007-04-27

Family

ID=29736145

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0311578-0A BR0311578A (pt) 2002-06-05 2003-06-05 seqüências de receptores cdr3 de células t e métodos para detecção

Country Status (16)

Country Link
EP (1) EP1530483B1 (pt)
JP (3) JP2005528910A (pt)
CN (1) CN1674931A (pt)
AT (1) ATE453727T1 (pt)
AU (1) AU2003237437B2 (pt)
BR (1) BR0311578A (pt)
CA (1) CA2485874A1 (pt)
DE (1) DE60330780D1 (pt)
IL (2) IL165194A (pt)
MX (1) MXPA04011646A (pt)
NO (1) NO20044945L (pt)
NZ (1) NZ537403A (pt)
PL (1) PL213315B1 (pt)
RU (1) RU2004139045A (pt)
WO (1) WO2003104407A2 (pt)
ZA (1) ZA200409792B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101495146B1 (ko) 2006-03-16 2015-02-24 트리스 파마 인코포레이티드 약물 - 이온교환 수지 복합체를 함유하는 변형 방출 제제
BR112015003120B1 (pt) 2012-08-15 2022-08-09 Tris Pharma , Inc Tablete mastigável de liberação estendida de metilfenidato e seu uso
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
CN108070644B (zh) * 2016-11-08 2021-06-29 国家卫生计生委科学技术研究所 一种妊娠高血压的诊断***
WO2018168949A1 (ja) * 2017-03-15 2018-09-20 学校法人兵庫医科大学 がん免疫療法の新規バイオマーカ
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165071A (en) * 1990-03-30 2008-06-05 Autoimmune Inc A peptide with the ability to stimulate a subset of T cells from multiple sclerosis patients
CA2362099C (en) * 1999-02-23 2014-05-13 Baylor College Of Medicine T cell receptor v.beta.-d.beta.-j.beta. sequence and methods for its detection

Also Published As

Publication number Publication date
EP1530483A4 (en) 2006-05-17
ATE453727T1 (de) 2010-01-15
CN1674931A (zh) 2005-09-28
JP2005528910A (ja) 2005-09-29
PL374723A1 (en) 2005-10-31
AU2003237437A1 (en) 2003-12-22
EP1530483A2 (en) 2005-05-18
IL165194A (en) 2010-11-30
IL165194A0 (en) 2005-12-18
NZ537403A (en) 2009-10-30
WO2003104407A2 (en) 2003-12-18
CA2485874A1 (en) 2003-12-18
RU2004139045A (ru) 2005-09-10
EP1530483B1 (en) 2009-12-30
WO2003104407A3 (en) 2005-03-24
IL206650A0 (en) 2011-07-31
MXPA04011646A (es) 2005-03-07
PL213315B1 (pl) 2013-02-28
NO20044945L (no) 2004-12-28
AU2003237437B2 (en) 2010-11-25
ZA200409792B (en) 2006-07-26
JP2013126420A (ja) 2013-06-27
DE60330780D1 (de) 2010-02-11
IL206650A (en) 2016-10-31
JP2010207226A (ja) 2010-09-24

Similar Documents

Publication Publication Date Title
IL206650A0 (en) T cell receptor cdr3 peptide for treating an autoimmune disease
IL129299A0 (en) Monoclonal antibodies antigens and diagnosis of malignant diseases
DE602005009856D1 (de) Verfahren zur reinigung von fsh
CY1112953T1 (el) Χρηση των αντι-cd100 αντισωματων
EA200300381A1 (ru) Нуклеиновые кислоты и полипептиды нового рецептора
BRPI0513135A (pt) bibliotecas de polinucleotìdeos, método de produção das mesmas, método de identificação de um polinucleotìdeo, região de ligação, meio adequado para uso em um, dispositivo eletrÈnico e dispositivo
DE69831007D1 (de) Humane checkpointkinase, hcds1, zusammensetzungen und verfahren
DK1100922T3 (da) Anvendelser af én eller flere borreliacide epitoper på ydermembranprotein C fra Borrelia burgdorferi (OspC) som vaccine
CY1105380T1 (el) Προτιμωμενα τμηματα της νευρικης νηματικης πρωτεϊνης και μεθοδοι χρησης αυτων
RU2007115411A (ru) Пептиды hsp60 и их apl-производные и фармацевтические композиции
DE69931482D1 (de) Isolierte peptide die aminosäuresequenzen von ny-eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen
EA200600738A1 (ru) Способ
ATE316577T1 (de) Das goodpasture-antigen bindende protein
CY1109946T1 (el) Τροποποιημενα πεπτιδια και η χρηση τους για τη θεραπεια αυτοανοσων νοσων
IL165364A (en) A method for identifying peptides that mimic an autoimmune antibody idiotype associated with autoimmune disease, peptides identified by the above method and their use
WO2004039334A3 (en) CALCIUM-SENSING RECEPTOR 2 (CaR2) AND METHODS FOR USING
HUP0400499A2 (hu) T-sejt-receptor Vbéta-Dbéta-Jbéta-szekvenciája és eljárások detektálására
AU2003235988A1 (en) Polynucleotide sequences encoding alkaline a-galactosidases and methods of using same
WO2004113566A3 (en) Disease related protein network
Kalliolias et al. Immunological basis of inflammatory arthritides
HUP0301111A2 (hu) Potenciálisan immundomináns acetilkolin-receptor oligopeptideket tartalmazó gyógyszerkészítmények és alkalmazásuk
AU2003302440A8 (en) Nucleic acid probes and method for detecting a target nucleic acid sequence comprise two or more cis- located nucleic acid regions
EP1986011A3 (en) Peptide epitopes recognized by disease promoting CD4+ T lymphocytes
GB0426960D0 (en) TGR-3 like protein receptor
AU4956901A (en) Novel human 7tm proteins and polynucleotides encoding the same

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2064 DE 27/07/2010.