BR0311578A - seqüências de receptores cdr3 de células t e métodos para detecção - Google Patents
seqüências de receptores cdr3 de células t e métodos para detecçãoInfo
- Publication number
- BR0311578A BR0311578A BRPI0311578-0A BR0311578A BR0311578A BR 0311578 A BR0311578 A BR 0311578A BR 0311578 A BR0311578 A BR 0311578A BR 0311578 A BR0311578 A BR 0311578A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- detection
- receptor sequences
- cell
- disclosed
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
Abstract
"SEQüêNCIAS DE RECEPTORES CDR3 DE CéLULAS T E MéTODOS PARA DETECçãO". A presente invenção refere-se geneticamente ao campo do tratamento de doenças auto-imunes, tais como MS (MS), artrite reumatóide (RA) e outras. Descreve-se métodos para tratar e monitorar uma doença auto-imune utilizando peptídeos receptores de células T. Descreve-se também seqüências de ácidos nucléicos e peptídeos de receptores de células T encontrados em uma população de pacientes com MS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38628702P | 2002-06-05 | 2002-06-05 | |
PCT/US2003/017873 WO2003104407A2 (en) | 2002-06-05 | 2003-06-05 | T cell receptor cdr3 sequences and methods for detection |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0311578A true BR0311578A (pt) | 2007-04-27 |
Family
ID=29736145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0311578-0A BR0311578A (pt) | 2002-06-05 | 2003-06-05 | seqüências de receptores cdr3 de células t e métodos para detecção |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1530483B1 (pt) |
JP (3) | JP2005528910A (pt) |
CN (1) | CN1674931A (pt) |
AT (1) | ATE453727T1 (pt) |
AU (1) | AU2003237437B2 (pt) |
BR (1) | BR0311578A (pt) |
CA (1) | CA2485874A1 (pt) |
DE (1) | DE60330780D1 (pt) |
IL (2) | IL165194A (pt) |
MX (1) | MXPA04011646A (pt) |
NO (1) | NO20044945L (pt) |
NZ (1) | NZ537403A (pt) |
PL (1) | PL213315B1 (pt) |
RU (1) | RU2004139045A (pt) |
WO (1) | WO2003104407A2 (pt) |
ZA (1) | ZA200409792B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101495146B1 (ko) | 2006-03-16 | 2015-02-24 | 트리스 파마 인코포레이티드 | 약물 - 이온교환 수지 복합체를 함유하는 변형 방출 제제 |
BR112015003120B1 (pt) | 2012-08-15 | 2022-08-09 | Tris Pharma , Inc | Tablete mastigável de liberação estendida de metilfenidato e seu uso |
US11590228B1 (en) | 2015-09-08 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine compositions |
CN108070644B (zh) * | 2016-11-08 | 2021-06-29 | 国家卫生计生委科学技术研究所 | 一种妊娠高血压的诊断*** |
WO2018168949A1 (ja) * | 2017-03-15 | 2018-09-20 | 学校法人兵庫医科大学 | がん免疫療法の新規バイオマーカ |
US11590081B1 (en) | 2017-09-24 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine tablets |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL165071A (en) * | 1990-03-30 | 2008-06-05 | Autoimmune Inc | A peptide with the ability to stimulate a subset of T cells from multiple sclerosis patients |
CA2362099C (en) * | 1999-02-23 | 2014-05-13 | Baylor College Of Medicine | T cell receptor v.beta.-d.beta.-j.beta. sequence and methods for its detection |
-
2003
- 2003-06-05 EP EP03736888A patent/EP1530483B1/en not_active Expired - Lifetime
- 2003-06-05 WO PCT/US2003/017873 patent/WO2003104407A2/en active Application Filing
- 2003-06-05 NZ NZ537403A patent/NZ537403A/en not_active IP Right Cessation
- 2003-06-05 BR BRPI0311578-0A patent/BR0311578A/pt not_active IP Right Cessation
- 2003-06-05 DE DE60330780T patent/DE60330780D1/de not_active Expired - Lifetime
- 2003-06-05 CA CA002485874A patent/CA2485874A1/en not_active Abandoned
- 2003-06-05 AU AU2003237437A patent/AU2003237437B2/en not_active Ceased
- 2003-06-05 RU RU2004139045/13A patent/RU2004139045A/ru not_active Application Discontinuation
- 2003-06-05 JP JP2004511467A patent/JP2005528910A/ja not_active Withdrawn
- 2003-06-05 CN CNA038186314A patent/CN1674931A/zh active Pending
- 2003-06-05 AT AT03736888T patent/ATE453727T1/de not_active IP Right Cessation
- 2003-06-05 MX MXPA04011646A patent/MXPA04011646A/es not_active Application Discontinuation
- 2003-06-05 PL PL374723A patent/PL213315B1/pl unknown
-
2004
- 2004-11-12 NO NO20044945A patent/NO20044945L/no not_active Application Discontinuation
- 2004-11-14 IL IL165194A patent/IL165194A/en not_active IP Right Cessation
- 2004-12-02 ZA ZA200409792A patent/ZA200409792B/en unknown
-
2010
- 2010-04-01 JP JP2010085593A patent/JP2010207226A/ja not_active Withdrawn
- 2010-06-27 IL IL206650A patent/IL206650A/en not_active IP Right Cessation
-
2013
- 2013-03-05 JP JP2013042552A patent/JP2013126420A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1530483A4 (en) | 2006-05-17 |
ATE453727T1 (de) | 2010-01-15 |
CN1674931A (zh) | 2005-09-28 |
JP2005528910A (ja) | 2005-09-29 |
PL374723A1 (en) | 2005-10-31 |
AU2003237437A1 (en) | 2003-12-22 |
EP1530483A2 (en) | 2005-05-18 |
IL165194A (en) | 2010-11-30 |
IL165194A0 (en) | 2005-12-18 |
NZ537403A (en) | 2009-10-30 |
WO2003104407A2 (en) | 2003-12-18 |
CA2485874A1 (en) | 2003-12-18 |
RU2004139045A (ru) | 2005-09-10 |
EP1530483B1 (en) | 2009-12-30 |
WO2003104407A3 (en) | 2005-03-24 |
IL206650A0 (en) | 2011-07-31 |
MXPA04011646A (es) | 2005-03-07 |
PL213315B1 (pl) | 2013-02-28 |
NO20044945L (no) | 2004-12-28 |
AU2003237437B2 (en) | 2010-11-25 |
ZA200409792B (en) | 2006-07-26 |
JP2013126420A (ja) | 2013-06-27 |
DE60330780D1 (de) | 2010-02-11 |
IL206650A (en) | 2016-10-31 |
JP2010207226A (ja) | 2010-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2064 DE 27/07/2010. |