BR0308506A - Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas - Google Patents

Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas

Info

Publication number
BR0308506A
BR0308506A BR0308506-6A BR0308506A BR0308506A BR 0308506 A BR0308506 A BR 0308506A BR 0308506 A BR0308506 A BR 0308506A BR 0308506 A BR0308506 A BR 0308506A
Authority
BR
Brazil
Prior art keywords
coenzyme
molecules
biological samples
analyzing
concentrations
Prior art date
Application number
BR0308506-6A
Other languages
English (en)
Inventor
Mitsuru Sakai
Yoshinori Sugimoto
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of BR0308506A publication Critical patent/BR0308506A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N2030/062—Preparation extracting sample from raw material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"MéTODO PARA ANALISAR CONCENTRAçõES DE MOLéCULAS DE COENZIMA A NAS AMOSTRAS BIOLóGICAS". A invenção é destinada a fornecer um método altamente sensível e altamente reprodutível para análise de coenzimas A (CoA) em uma amostra biológica caracterizado pelo fato de envolver a etapa de extrair a amostra biológica mediante o uso de uma solução fortemente ácida, a etapa de extração na fase sólida, a etapa de adicionar um padrão interno, e a etapa de detecção com o uso de LC-MS.
BR0308506-6A 2002-03-25 2003-03-24 Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas BR0308506A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002082821 2002-03-25
PCT/JP2003/003521 WO2003081229A1 (fr) 2002-03-25 2003-03-24 Technique de dosage de coenzymes dans un echantillon biologique

Publications (1)

Publication Number Publication Date
BR0308506A true BR0308506A (pt) 2004-12-21

Family

ID=28449161

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308506-6A BR0308506A (pt) 2002-03-25 2003-03-24 Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas

Country Status (10)

Country Link
US (1) US20050118666A1 (pt)
EP (1) EP1489411A4 (pt)
JP (1) JP3780283B2 (pt)
KR (1) KR20040094856A (pt)
CN (1) CN1329730C (pt)
AU (1) AU2003221008B2 (pt)
BR (1) BR0308506A (pt)
CA (1) CA2480306A1 (pt)
MX (1) MXPA04008788A (pt)
WO (1) WO2003081229A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009110873A2 (en) * 2007-12-05 2009-09-11 The Gov. Of The Usa, As Represented By The Secretary Dept. Of Health & Human Services Improved viral protein quantification and vaccine quality control therewith
JP5624709B2 (ja) * 2008-03-13 2014-11-12 大日本住友製薬株式会社 内因性代謝物の分析方法
CN102326073B (zh) * 2009-03-05 2013-11-13 株式会社日立高新技术 分析装置
JP5859310B2 (ja) * 2009-10-29 2016-02-10 学校法人 埼玉医科大学 母乳または飲食品がアトピー性皮膚炎の発症を誘導する危険性を評価する方法、およびアトピー性皮膚炎の発症を誘導する危険性が減少された母乳または飲食品
JP6311387B2 (ja) * 2014-03-26 2018-04-18 株式会社島津製作所 化合物分析方法、化合物分析装置、及び化合物分析用プログラム
CN106324165A (zh) * 2015-07-02 2017-01-11 中国科学院大连化学物理研究所 一种微量细胞培养液中离脂肪酸的测定方法
CN107515261A (zh) * 2017-08-18 2017-12-26 开封康诺药业有限公司 一种高效液相色谱法测定辅酶i的方法
CN109270202B (zh) * 2018-10-11 2020-12-01 中国药科大学 一种动物肝脏内乙酰辅酶a的液质联用测定方法
CA3179966A1 (en) * 2020-04-09 2021-10-14 HepQuant, LLC Improved methods for evaluating liver function
CN115407002A (zh) * 2021-05-28 2022-11-29 中国科学院遗传与发育生物学研究所 一种检测植物材料中植物内源小肽激素的纯化富集方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338686A (en) * 1992-04-29 1994-08-16 Hellerstein Marc K Method for measuring in vivo synthesis of biopolymers
CA2292768C (en) * 1997-06-05 2011-11-29 Calgene Llc Fatty acyl-coa: fatty alcohol acyltransferases
ATE253126T1 (de) * 1998-08-25 2003-11-15 Univ Washington Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
US6391649B1 (en) * 1999-05-04 2002-05-21 The Rockefeller University Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy

Also Published As

Publication number Publication date
CN1643375A (zh) 2005-07-20
KR20040094856A (ko) 2004-11-10
CN1329730C (zh) 2007-08-01
AU2003221008B2 (en) 2007-08-16
EP1489411A1 (en) 2004-12-22
AU2003221008A1 (en) 2003-10-08
MXPA04008788A (es) 2005-06-20
JP3780283B2 (ja) 2006-05-31
JPWO2003081229A1 (ja) 2005-07-28
CA2480306A1 (en) 2003-10-02
US20050118666A1 (en) 2005-06-02
WO2003081229A1 (fr) 2003-10-02
EP1489411A4 (en) 2007-03-14

Similar Documents

Publication Publication Date Title
Saar-Reismaa et al. In situ determination of illegal drugs in oral fluid by portable capillary electrophoresis with deep UV excited fluorescence detection
BRPI0509068A (pt) métodos para determinar quantitativamente heparinas de constituição especìfica ou heparinas de baixo peso molecular usando hplc
Kubáň et al. In situ determination of nerve agents in various matrices by portable capillary electropherograph with contactless conductivity detection
BRPI0613478B8 (pt) dispositivo para análise quantitativa de um perfil de metabólito
BRPI0519119A2 (pt) sistema colorimÉtrico e mÉtodo para detectar um analito
BR9906357A (pt) Aparelho e processo para detectar um gás em um fluido dielétrico.
DK1570274T3 (da) Analysator og analysefremgangsmåde og en væskekassette
ATE408813T1 (de) Nachweis von analyten
CY1107490T1 (el) Μεθοδος για την ταυτοποιηση δειγματος σε θηλαστικα καθως και κιτ για την εκτελεση αυτης της μεθοδου
Zhang et al. A direct and rapid method to determine cyanide in urine by capillary electrophoresis
ATE466659T1 (de) Probenahmesystem mit phosphataseinhibitor
BR0308506A (pt) Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas
WO2009013884A1 (ja) 鉛濃度測定用試薬及び鉛濃度測定方法
WO2006047662A3 (en) Method and apparatus for sediment characterization
Švagera et al. Study of disulfide reduction and alkyl chloroformate derivatization of plasma sulfur amino acids using gas chromatography–mass spectrometry
BR0317394A (pt) Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal
Saar-Reismaa et al. Rapid and sensitive capillary electrophoresis method for the analysis of Ecstasy in an oral fluid
BRPI0400082A (pt) Método analìtico para a detecção e quantificação de aditivos de combustìvel
Thredgold et al. Direct detection of histamine in fish flesh using microchip electrophoresis with capacitively coupled contactless conductivity detection
BRPI0416296A (pt) aparelho e método para remover gás antes de detecção e/ou da análise de amostra
Tanaka et al. Quantitative analysis of sulfur-related metabolites during cadmium stress response in yeast by capillary electrophoresis–mass spectrometry
Teixeira et al. Cannabis and driving: the use of LC–MS to detect Δ9-tetrahydrocannabinol (Δ9-THC) in oral fluid samples
Hui et al. Analysis of ammonia and aliphatic amines in environmental water by micellar electrokinetic chromatography and QSPR modeling of electrophoretic migration time
Chen et al. Separation and determination of peptide hormones by capillary electrophoresis with laser-induced fluorescence coupled with transient pseudo-isotachophoresis preconcentration
EA200500157A1 (ru) Хранение и обнаружение нуклеиновой кислоты, нанесенной на твердый носитель

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. E 8A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2125 DE 27/09/2011.