BR0212927A - Formas pseudopolimórficas de carvedilol - Google Patents

Formas pseudopolimórficas de carvedilol

Info

Publication number
BR0212927A
BR0212927A BR0212927-2A BR0212927A BR0212927A BR 0212927 A BR0212927 A BR 0212927A BR 0212927 A BR0212927 A BR 0212927A BR 0212927 A BR0212927 A BR 0212927A
Authority
BR
Brazil
Prior art keywords
carvedilol
forms
pseudopolymorphic forms
pseudopolymorphic
pseudopolimorphic
Prior art date
Application number
BR0212927-2A
Other languages
English (en)
Inventor
Andre Gerard Bubendorf
Rolf-Dieter Gabel
Michael Henningsen
Siegfried Krimmer
Guenter Neugebauer
Walter Preis
Alexander Wirl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0212927A publication Critical patent/BR0212927A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"FORMAS PSEUDOPOLIMóRFICAS DE CARVEDILOL". A presente invenção refere-se a formas pseudopolimórficas de (<sym>) 1-(4-carbazolilóxi)-3-[2-metoxifenóxi) etilamino]-2-propanol (carvedilol) ou de formas opticamente ativas de sais farmaceuticamente aceitáveis do mesmo, aos processos para a preparação dos mesmos e a composições farmacêuticas que contêm as mesmas.
BR0212927-2A 2001-09-28 2002-09-18 Formas pseudopolimórficas de carvedilol BR0212927A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01123422 2001-09-28
PCT/EP2002/010451 WO2003029214A1 (en) 2001-09-28 2002-09-18 Pseudopolymorphic forms of carvedilol

Publications (1)

Publication Number Publication Date
BR0212927A true BR0212927A (pt) 2004-10-13

Family

ID=8178782

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212927-2A BR0212927A (pt) 2001-09-28 2002-09-18 Formas pseudopolimórficas de carvedilol

Country Status (20)

Country Link
US (3) US20030119893A1 (pt)
EP (1) EP1432681B1 (pt)
JP (1) JP2005507899A (pt)
KR (1) KR100752549B1 (pt)
CN (1) CN1308307C (pt)
AR (1) AR036689A1 (pt)
AT (1) ATE369339T1 (pt)
AU (1) AU2002338726B2 (pt)
BR (1) BR0212927A (pt)
CA (1) CA2460486A1 (pt)
DE (1) DE60221683T2 (pt)
ES (1) ES2291503T3 (pt)
GT (1) GT200200198A (pt)
MX (1) MXPA04002826A (pt)
PA (1) PA8555201A1 (pt)
PE (1) PE20030448A1 (pt)
PL (1) PL370412A1 (pt)
RU (1) RU2308449C2 (pt)
UY (1) UY27461A1 (pt)
WO (1) WO2003029214A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699997B2 (en) * 2000-06-28 2004-03-02 Teva Pharmaceutical Industries Ltd. Carvedilol
PL371409A1 (en) * 2002-01-15 2005-06-13 Teva Pharmaceutical Industries Ltd. Crystalline solids of carvedilol and processes for their preparation
JP2005533823A (ja) 2002-06-27 2005-11-10 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド リン酸カルベジロール塩および／またはその溶媒和物、対応する組成物、および／または治療方法
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
EP1781611A1 (en) * 2005-06-09 2007-05-09 Teva Pharmaceutical Industries Ltd. Crystalline forms of carvedilol and processes for their preparation
EP1991527A2 (en) * 2006-06-28 2008-11-19 Teva Pharmaceutical Industries Ltd Polymorphous forms of carvedilol phosphate
WO2008070072A2 (en) * 2006-12-01 2008-06-12 Mutual Pharmaceutical Company, Inc. Carvedilol forms, compositions, and methods of preparation thereof
US20090028935A1 (en) * 2006-12-01 2009-01-29 Kristin Arnold Carvedilol forms, compositions, and methods of preparation thereof
EP2114881A1 (en) * 2007-02-26 2009-11-11 Teva Pharmaceutical Industries Ltd. Process for the purification of carvedilol or its salts thereof
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
TWI415604B (zh) 2009-09-29 2013-11-21 Tsh Biopharm Corp Ltd 調控釋放卡菲蒂羅劑型
US20110229564A1 (en) * 2010-03-22 2011-09-22 Amneal Pharmaceuticals, L.L.C. Pharmaceutical Compositions Of Carvedilol Salts And Process For Preparation Thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
US5393772A (en) * 1993-11-24 1995-02-28 Boehringer Mannheim Pharmaceuticals Corporation Use of, and method of treatment using, hydroxycarbazole compounds for inhibition of smooth muscle migration and proliferation
EP0893440A1 (en) * 1997-07-22 1999-01-27 Roche Diagnostics GmbH Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
US6699997B2 (en) * 2000-06-28 2004-03-02 Teva Pharmaceutical Industries Ltd. Carvedilol

Also Published As

Publication number Publication date
CA2460486A1 (en) 2003-04-10
US20040198812A1 (en) 2004-10-07
JP2005507899A (ja) 2005-03-24
AR036689A1 (es) 2004-09-29
ATE369339T1 (de) 2007-08-15
EP1432681B1 (en) 2007-08-08
US20060148878A1 (en) 2006-07-06
UY27461A1 (es) 2003-06-30
DE60221683T2 (de) 2008-04-30
WO2003029214A1 (en) 2003-04-10
GT200200198A (es) 2003-06-19
AU2002338726B9 (en) 2003-04-14
PL370412A1 (en) 2005-05-30
RU2308449C2 (ru) 2007-10-20
RU2004113209A (ru) 2005-05-20
ES2291503T3 (es) 2008-03-01
CN1558900A (zh) 2004-12-29
PA8555201A1 (es) 2003-12-10
US20030119893A1 (en) 2003-06-26
AU2002338726B2 (en) 2007-03-15
MXPA04002826A (es) 2004-07-02
DE60221683D1 (en) 2007-09-20
KR100752549B1 (ko) 2007-08-30
PE20030448A1 (es) 2003-06-19
KR20040047872A (ko) 2004-06-05
CN1308307C (zh) 2007-04-04
EP1432681A1 (en) 2004-06-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010.