BR0208812A - Derivados fenil heterociclil éter como inibidores de recaptação de serotonina - Google Patents

Derivados fenil heterociclil éter como inibidores de recaptação de serotonina

Info

Publication number
BR0208812A
BR0208812A BR0208812-6A BR0208812A BR0208812A BR 0208812 A BR0208812 A BR 0208812A BR 0208812 A BR0208812 A BR 0208812A BR 0208812 A BR0208812 A BR 0208812A
Authority
BR
Brazil
Prior art keywords
serotonin reuptake
reuptake inhibitors
ether derivatives
phenyl heterocyclyl
phenyl
Prior art date
Application number
BR0208812-6A
Other languages
English (en)
Inventor
Mavis Diane Adam
Mark David Andrews
Geoffrey Edward Gymer
David Hepworth
Harry Ralph Howard Jr
Donald Stuart Middleton
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR0208812A publication Critical patent/BR0208812A/pt

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

"DERIVADOS FENIL HETEROCICLIL éTER COMO INIBIDORES DE RECAPTAçãO DE SEROTONINA". A presente invenção refere-se a compostos de fórmula I que exibem inibidores seletivos de recaptação de serotonina.
BR0208812-6A 2001-04-11 2002-03-27 Derivados fenil heterociclil éter como inibidores de recaptação de serotonina BR0208812A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0109103.2A GB0109103D0 (en) 2001-04-11 2001-04-11 Novel compounds
PCT/IB2002/001032 WO2002083643A1 (en) 2001-04-11 2002-03-27 Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors

Publications (1)

Publication Number Publication Date
BR0208812A true BR0208812A (pt) 2004-03-09

Family

ID=9912700

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208812-6A BR0208812A (pt) 2001-04-11 2002-03-27 Derivados fenil heterociclil éter como inibidores de recaptação de serotonina

Country Status (44)

Country Link
EP (1) EP1377550B9 (pt)
JP (1) JP2005504728A (pt)
KR (1) KR100570376B1 (pt)
CN (1) CN1656072A (pt)
AP (1) AP1543A (pt)
AR (1) AR035818A1 (pt)
AT (1) ATE281435T1 (pt)
AU (1) AU2002244898B2 (pt)
BG (1) BG108204A (pt)
BR (1) BR0208812A (pt)
CA (1) CA2443699A1 (pt)
CZ (1) CZ20032677A3 (pt)
DE (1) DE60201819T2 (pt)
DO (1) DOP2002000371A (pt)
EA (1) EA008936B1 (pt)
EC (1) ECSP034802A (pt)
EE (1) EE200300498A (pt)
ES (1) ES2227448T3 (pt)
GB (1) GB0109103D0 (pt)
GE (1) GEP20053590B (pt)
GT (1) GT200200071A (pt)
HR (1) HRP20030824A2 (pt)
HU (1) HUP0303880A2 (pt)
IL (2) IL158141A0 (pt)
IS (1) IS6960A (pt)
MA (1) MA27010A1 (pt)
MX (1) MXPA03009383A (pt)
MY (1) MY136262A (pt)
NO (1) NO20034525L (pt)
NZ (1) NZ528481A (pt)
OA (1) OA12500A (pt)
PA (1) PA8543701A1 (pt)
PE (1) PE20021003A1 (pt)
PL (1) PL373533A1 (pt)
PT (1) PT1377550E (pt)
RS (1) RS79703A (pt)
SI (1) SI1377550T1 (pt)
SK (1) SK12452003A3 (pt)
SV (1) SV2003000981A (pt)
TN (1) TNSN03090A1 (pt)
UA (1) UA74430C2 (pt)
UY (1) UY27250A1 (pt)
WO (1) WO2002083643A1 (pt)
ZA (1) ZA200307507B (pt)

Families Citing this family (13)

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US7087758B2 (en) * 2001-04-06 2006-08-08 Smithkline Beecham Corporation Quinoline inhibitors of hyaki and hyak3 kinases
CA2499690C (en) * 2002-09-19 2011-05-24 Eli Lilly And Company Diaryl ethers as opioid receptor antagonist
GB0318706D0 (en) * 2003-08-08 2003-09-10 Pfizer Ltd Selective serotonin reuptake inhibitors in the treatment of disease
WO2006008635A1 (en) * 2004-07-14 2006-01-26 Pfizer Limited Process for the preparation of a 3-phenoxy-pyridine derivative
NZ564759A (en) 2005-06-30 2011-08-26 Prosidion Ltd GPCR agonists
EP1999119A2 (en) 2006-02-15 2008-12-10 Abbott Laboratories Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome
US7928243B2 (en) * 2006-12-21 2011-04-19 Abbott Laboratories Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
ATE523507T1 (de) 2007-01-04 2011-09-15 Prosidion Ltd Piperidin-gpcr-agonisten
DE102008053242A1 (de) 2008-10-25 2010-05-06 Saltigo Gmbh Heteroaryl-Arylether
JP2014001199A (ja) * 2012-01-25 2014-01-09 Ishihara Sangyo Kaisha Ltd 有害生物防除剤
KR102192554B1 (ko) 2013-03-13 2020-12-18 에스케이바이오팜 주식회사 탈력발작의 치료
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
US20220185815A1 (en) 2019-03-06 2022-06-16 Daiichi Sankyo Company, Limited Pyrrolopyrazole derivative

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Publication number Priority date Publication date Assignee Title
NZ512910A (en) * 1999-02-23 2003-11-28 Pfizer Prod Inc Monoamine reuptake inhibitors for treatment of CNS disorders
EA005820B1 (ru) * 1999-05-21 2005-06-30 Биовитрум Аб Агонисты и антагонисты рецепторов 5-ht
PL355289A1 (en) * 1999-10-13 2004-04-05 Pfizer Products Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors

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NO20034525D0 (no) 2003-10-09
IL158141A0 (en) 2004-03-28
CZ20032677A3 (cs) 2004-06-16
EP1377550B9 (en) 2005-11-23
KR100570376B1 (ko) 2006-04-11
EE200300498A (et) 2004-02-16
JP2005504728A (ja) 2005-02-17
WO2002083643A1 (en) 2002-10-24
EP1377550A1 (en) 2004-01-07
MA27010A1 (fr) 2004-12-20
MXPA03009383A (es) 2004-01-29
ZA200307507B (en) 2004-11-19
DE60201819T2 (de) 2005-11-03
UA74430C2 (uk) 2005-12-15
PE20021003A1 (es) 2002-11-12
HRP20030824A2 (en) 2005-08-31
GEP20053590B (en) 2005-07-25
IL158141A (en) 2007-10-31
SK12452003A3 (sk) 2004-08-03
PL373533A1 (en) 2005-09-05
SI1377550T1 (en) 2005-02-28
KR20030088133A (ko) 2003-11-17
RS79703A (en) 2006-12-15
PA8543701A1 (es) 2004-05-26
CN1656072A (zh) 2005-08-17
TNSN03090A1 (fr) 2005-12-23
EP1377550B1 (en) 2004-11-03
ATE281435T1 (de) 2004-11-15
SV2003000981A (es) 2003-07-29
GT200200071A (es) 2003-01-31
EA200300988A1 (ru) 2004-04-29
ES2227448T3 (es) 2005-04-01
MY136262A (en) 2008-09-30
HUP0303880A2 (hu) 2004-04-28
BG108204A (bg) 2004-12-30
CA2443699A1 (en) 2002-10-24
EA008936B1 (ru) 2007-10-26
NZ528481A (en) 2006-02-24
AP2002002468A0 (en) 2002-06-30
AP1543A (en) 2006-01-11
GB0109103D0 (en) 2001-05-30
AR035818A1 (es) 2004-07-14
UY27250A1 (es) 2002-12-31
NO20034525L (no) 2003-12-08
DE60201819D1 (en) 2004-12-09
PT1377550E (pt) 2005-01-31
ECSP034802A (es) 2003-12-01
IS6960A (is) 2003-09-18
AU2002244898B2 (en) 2007-05-24
DOP2002000371A (es) 2002-10-15
OA12500A (en) 2006-05-24

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