BR0114891A - Genes encoding new proteins with pesticide activity against beetles - Google Patents
Genes encoding new proteins with pesticide activity against beetlesInfo
- Publication number
- BR0114891A BR0114891A BR0114891-5A BR0114891A BR0114891A BR 0114891 A BR0114891 A BR 0114891A BR 0114891 A BR0114891 A BR 0114891A BR 0114891 A BR0114891 A BR 0114891A
- Authority
- BR
- Brazil
- Prior art keywords
- activity against
- pesticidal
- nucleic acids
- genes encoding
- pesticidal activity
- Prior art date
Links
- 230000000361 pesticidal effect Effects 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 241000254173 Coleoptera Species 0.000 title 1
- 241000607479 Yersinia pestis Species 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
- 108700003918 Bacillus Thuringiensis insecticidal crystal Proteins 0.000 abstract 1
- 241000193388 Bacillus thuringiensis Species 0.000 abstract 1
- 229940097012 bacillus thuringiensis Drugs 0.000 abstract 1
- 239000002158 endotoxin Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Insects & Arthropods (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"GENES CODIFICANDO NOVAS PROTEìNAS COM ATIVIDADE PESTICIDA CONTRA COLEóPTEROS". A invenção provê ácidos nucléicos, variantes e fragmentos dos mesmos, obtidos das cepas de Bacillus thuringiensis codificando endotoxinas delta possuindo atividade pesticida contra pragas da ordem dos Coleópteros. A invenção adicionalmente provê ácidos nucléicos mutagenizados que foram modificados para codificar endotoxinas possuindo atividade pesticida e/ou especificidade de praga alterada. Concretizações adicionais da invenção fornecem ácidos nucléicos isolados codificando proteínas pesticidas, composições pesticidas, cassetes de expressão, microorganismos transformados e plantas compreendendo um ácido nucléico da invenção. Estas composições encontram utilização nos processos para controle das pragas, especialmente pragas de plantas."GENES ENCODING NEW PROTEIN WITH PESTICIDAL ACTIVITY AGAINST COLLEOPTERS". The invention provides nucleic acids, variants and fragments thereof obtained from strains of Bacillus thuringiensis encoding delta endotoxins having pesticidal activity against Coleopteran pests. The invention further provides mutagenized nucleic acids which have been modified to encode endotoxins having pesticidal activity and / or altered pest specificity. Additional embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, expression cassettes, transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in pest control processes, especially plant pests.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24283800P | 2000-10-24 | 2000-10-24 | |
US10/032,717 US7605304B2 (en) | 2000-10-24 | 2001-10-23 | Genes encoding novel bacillus thuringiensis proteins with pesticidal activity against coleopterans |
PCT/US2001/045468 WO2002034774A2 (en) | 2000-10-24 | 2001-10-24 | Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0114891A true BR0114891A (en) | 2005-06-28 |
Family
ID=26708782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0114891-5A BR0114891A (en) | 2000-10-24 | 2001-10-24 | Genes encoding new proteins with pesticide activity against beetles |
Country Status (11)
Country | Link |
---|---|
US (3) | US7605304B2 (en) |
EP (1) | EP1356054B1 (en) |
AT (1) | ATE338820T1 (en) |
AU (1) | AU2002228705A1 (en) |
BR (1) | BR0114891A (en) |
CA (1) | CA2426793C (en) |
DE (1) | DE60122931T2 (en) |
ES (1) | ES2271098T3 (en) |
HU (1) | HU228699B1 (en) |
MX (1) | MXPA03003666A (en) |
WO (1) | WO2002034774A2 (en) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2490548A1 (en) | 2002-06-26 | 2004-01-08 | E.I. Du Pont De Nemours And Company | Genes encoding proteins with pesticidal activity |
US7462760B2 (en) * | 2002-06-26 | 2008-12-09 | Pioneer Hi-Bred International, Inc. | Genes encoding plant protease-resistant pesticidal proteins and method of their use |
CA2551011C (en) | 2003-12-23 | 2013-04-16 | Pioneer Hi-Bred International, Inc. | Plant activation of insect toxin |
US20060212964A9 (en) * | 2004-02-20 | 2006-09-21 | Pioneer Hi-Bred International, Inc. | Methods for enhancing insect resistance in plants |
CN100532555C (en) * | 2004-11-16 | 2009-08-26 | 中国农业科学院植物保护研究所 | Highly efficient cry8F gene for Coleoptera pest, expression protein and application thereof |
CN1323159C (en) * | 2004-11-16 | 2007-06-27 | 中国农业科学院植物保护研究所 | Bacillus thringiensis strain and gene with high effect on coleoptera pests |
US7781648B2 (en) * | 2005-05-18 | 2010-08-24 | Board Of Trustees Of Michigan State University | Resistance to soybean aphid in early maturing soybean germplasm |
MX2007015538A (en) * | 2005-06-08 | 2008-03-06 | Pionner Hi Bred International | Insect-specific protease recognition sequences. |
US7449552B2 (en) * | 2006-04-14 | 2008-11-11 | Pioneer Hi-Bred International, Inc. | Bacillus thuringiensis cry gene and protein |
US7329736B2 (en) * | 2006-04-14 | 2008-02-12 | Pioneer Hi-Bred International, Inc. | Bacillus thuringiensis cry gene and protein |
US9133475B2 (en) | 2008-11-26 | 2015-09-15 | Board Of Trustees Of Michigan State University | Aphid resistant soybean plants |
US20100210460A1 (en) | 2009-02-19 | 2010-08-19 | Pioneer Hi-Bred International, Inc. | Blended refuge deployment via manipulation during hybrid seed production |
JP2012529910A (en) * | 2009-06-16 | 2012-11-29 | ダウ アグロサイエンシィズ エルエルシー | DIG-5 insecticidal CRY toxin |
WO2011009182A2 (en) | 2009-07-24 | 2011-01-27 | Embrapa - Empresa Brasileira De Pesquisa Agropecuária | Isolated nucleic acid molecule, genetic construct, vector, transgenic cell, method for producing a transgenic cell and plant, isolated and purified polypeptide, biodegradable pesticide composition, pest control method, method for producing transgenic strains resistant to insect pests |
WO2012055982A2 (en) * | 2010-10-27 | 2012-05-03 | Devgen Nv | Down-regulating gene expression in insect pests |
US9125419B2 (en) * | 2012-08-14 | 2015-09-08 | Marrone Bio Innovations, Inc. | Bacillus sp. strain with antifungal, antibacterial and growth promotion activity |
CA2836403A1 (en) | 2013-01-04 | 2014-07-04 | Board Of Trustees Of Michigan State University | New sources of aphid resistance in soybean plants |
WO2014159306A1 (en) | 2013-03-13 | 2014-10-02 | Pioneer Hi-Bred International, Inc. | Glyphosate application for weed control in brassica |
CN105339380A (en) | 2013-03-14 | 2016-02-17 | 先锋国际良种公司 | Compositions and methods to control insect pests |
BR112015023709A2 (en) | 2013-03-15 | 2017-07-18 | Pioneer Hi Bred Int | phi-4 polypeptide, polynucleotide, composition, method for inhibiting growth, method for controlling a population, plant, seed, expression cassette, method for expressing a polynucleotide in a plant, method for protecting a plant, fusion protein |
WO2015023846A2 (en) | 2013-08-16 | 2015-02-19 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
BR122020001770B1 (en) | 2013-09-13 | 2022-11-29 | Pioneer Hi-Bred International, Inc | DNA CONSTRUCTION, METHOD FOR OBTAINING A TRANSGENIC PLANT, FUSION PROTEIN, METHOD FOR CONTROLLING AN INSECT PEST POPULATION, METHOD FOR INHIBITING THE GROWTH OR KILLING AN INSECT PEST |
WO2015120270A1 (en) | 2014-02-07 | 2015-08-13 | Pioneer Hi Bred International, Inc. | Insecticidal proteins and methods for their use |
CN106536545A (en) | 2014-02-07 | 2017-03-22 | 先锋国际良种公司 | Insecticidal proteins and methods for their use |
JP5839644B1 (en) * | 2014-02-18 | 2016-01-06 | 日本写真印刷株式会社 | Pest control sheet |
UY36057A (en) * | 2014-03-28 | 2015-10-30 | Monsanto Technology Llc | ACTIVE PESTICIDE PROTEINS AGAINST COLEOPTER INSECTS, RECOMBINATING NUCLEIC ACID, POLYPEPTIDE, COMPOSITION, METHOD FOR CONTROLLING INSECTS, PLANTS AND THEIR PARTS |
US10028510B2 (en) * | 2014-08-28 | 2018-07-24 | Dow Agrosciences Llc | DIG-17 insecticidal cry toxins |
CA2961733A1 (en) | 2014-09-17 | 2016-03-24 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
MX2017004745A (en) | 2014-10-16 | 2017-10-20 | Pioner Hi-Bred Int Inc | Insecticidal proteins and methods for their use. |
EP3212000B1 (en) | 2014-10-27 | 2020-11-25 | Newleaf Symbiotics, Inc. | Methods and compositions for controlling corn rootworm |
WO2016099916A1 (en) | 2014-12-19 | 2016-06-23 | E. I. Du Pont De Nemours And Company | Polylactic acid compositions with accelerated degradation rate and increased heat stability |
WO2016186986A1 (en) | 2015-05-19 | 2016-11-24 | Pioneer Hi Bred International Inc | Insecticidal proteins and methods for their use |
CA2986265A1 (en) | 2015-06-16 | 2016-12-22 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
CN116003550A (en) | 2015-08-06 | 2023-04-25 | 先锋国际良种公司 | Insecticidal proteins of plant origin and methods of use thereof |
JP2018527931A (en) | 2015-08-28 | 2018-09-27 | パイオニア ハイ−ブレッド インターナショナル, インコーポレイテッド | OCRROBACTRUM-mediated transformation of plants |
US11028407B2 (en) | 2016-04-19 | 2021-06-08 | Pioneer Hi-Bred International, Inc. | Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof |
CA3018384A1 (en) | 2016-05-04 | 2017-11-09 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
EP3472323A1 (en) | 2016-06-16 | 2019-04-24 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
UA127388C2 (en) | 2016-06-24 | 2023-08-09 | Піонір Хай-Бред Інтернешнл, Інк. | Plant regulatory elements and methods of use thereof |
EP3478052B1 (en) | 2016-07-01 | 2021-08-25 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
US20210292778A1 (en) | 2016-07-12 | 2021-09-23 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
BR112019008800A2 (en) | 2016-11-01 | 2019-07-16 | Pioneer Hi Bred Int | insecticidal polypeptide, insecticidal composition, recombinant polynucleotide, dna construct, plant cell or transgenic plant, method for inhibiting growth or exterminating an agricultural insect pest population, method for inhibiting growth or exterminating an insect pest, method for controlling lepidoptera and / or coleoptera insect infestation in a transgenic plant and provide insect resistance management and use of at least one insecticide polypeptide |
WO2018111551A1 (en) | 2016-12-14 | 2018-06-21 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
CA3046226A1 (en) | 2016-12-22 | 2018-06-28 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
WO2018140214A1 (en) | 2017-01-24 | 2018-08-02 | Pioneer Hi-Bred International, Inc. | Nematicidal protein from pseudomonas |
US20190390219A1 (en) | 2017-02-08 | 2019-12-26 | Pioneer Hi-Bred International, Inc. | Insecticidal combinations of plant derived insecticidal proteins and methods for their use |
EP3622076A1 (en) | 2017-05-11 | 2020-03-18 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
US20200165626A1 (en) | 2017-10-13 | 2020-05-28 | Pioneer Hi-Bred International, Inc. | Virus-induced gene silencing technology for insect control in maize |
EP3759489A1 (en) | 2018-03-02 | 2021-01-06 | Pioneer Hi-Bred International, Inc. | Plant health assay |
CN111867377B (en) | 2018-03-14 | 2023-05-23 | 先锋国际良种公司 | Insecticidal proteins from plants and methods of use thereof |
BR112020018675A2 (en) | 2018-03-14 | 2021-01-05 | Pioneer Hi-Bred International, Inc. | INSECTICIDE PROTEINS OF PLANTS AND METHODS FOR THEIR USE |
BR112020023800A2 (en) | 2018-05-22 | 2021-02-23 | Pioneer Hi-Bred International, Inc. | plant regulatory elements and methods of using them |
CA3106444A1 (en) | 2018-08-29 | 2020-03-05 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for conferring pesticidal activity to plants |
TW202142114A (en) | 2020-02-04 | 2021-11-16 | 美商陶氏農業科學公司 | Compositions having pesticidal utility and processes related thereto |
BR112022027035A2 (en) | 2020-07-14 | 2023-04-11 | Pioneer Hi Bred Int | INSECTICIDAL PROTEINS AND METHODS FOR THE USE OF THEM |
BR112023002603A2 (en) | 2020-08-10 | 2023-04-04 | Pioneer Hi Bred Int | REGULATORY ELEMENTS OF PLANT AND METHODS OF THEIR USE |
TW202345696A (en) | 2022-05-18 | 2023-12-01 | 美商科迪華農業科技有限責任公司 | Compositions having pesticidal utility and processes related thereto |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554534A (en) * | 1991-12-16 | 1996-09-10 | Mycogen Corporation | Bacillus thuringiensis toxins active against scarab pests |
US5185148A (en) | 1991-12-16 | 1993-02-09 | Mycogen Corporation | Process for controlling scarab pests with Bacillus thuringiensis isolates |
US5837458A (en) * | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
US5659123A (en) | 1994-08-26 | 1997-08-19 | Plant Genetic Systems, N.V. | Diabrotica toxins |
US5942664A (en) | 1996-11-27 | 1999-08-24 | Ecogen, Inc. | Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants |
US7462760B2 (en) * | 2002-06-26 | 2008-12-09 | Pioneer Hi-Bred International, Inc. | Genes encoding plant protease-resistant pesticidal proteins and method of their use |
CA2490548A1 (en) * | 2002-06-26 | 2004-01-08 | E.I. Du Pont De Nemours And Company | Genes encoding proteins with pesticidal activity |
CA2551011C (en) | 2003-12-23 | 2013-04-16 | Pioneer Hi-Bred International, Inc. | Plant activation of insect toxin |
MX2007015538A (en) * | 2005-06-08 | 2008-03-06 | Pionner Hi Bred International | Insect-specific protease recognition sequences. |
-
2001
- 2001-10-23 US US10/032,717 patent/US7605304B2/en not_active Expired - Fee Related
- 2001-10-24 AT AT01988728T patent/ATE338820T1/en not_active IP Right Cessation
- 2001-10-24 CA CA2426793A patent/CA2426793C/en not_active Expired - Fee Related
- 2001-10-24 HU HU0302523A patent/HU228699B1/en not_active IP Right Cessation
- 2001-10-24 AU AU2002228705A patent/AU2002228705A1/en not_active Abandoned
- 2001-10-24 MX MXPA03003666A patent/MXPA03003666A/en active IP Right Grant
- 2001-10-24 WO PCT/US2001/045468 patent/WO2002034774A2/en active IP Right Grant
- 2001-10-24 DE DE60122931T patent/DE60122931T2/en not_active Expired - Lifetime
- 2001-10-24 ES ES01988728T patent/ES2271098T3/en not_active Expired - Lifetime
- 2001-10-24 BR BR0114891-5A patent/BR0114891A/en not_active Application Discontinuation
- 2001-10-24 EP EP01988728A patent/EP1356054B1/en not_active Expired - Lifetime
-
2003
- 2003-04-16 US US10/414,637 patent/US7696412B2/en not_active Expired - Fee Related
-
2009
- 2009-05-27 US US12/472,997 patent/US8188036B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20090291896A1 (en) | 2009-11-26 |
US7696412B2 (en) | 2010-04-13 |
ES2271098T3 (en) | 2007-04-16 |
HUP0302523A3 (en) | 2005-11-28 |
WO2002034774A3 (en) | 2003-08-14 |
DE60122931D1 (en) | 2006-10-19 |
CA2426793C (en) | 2012-03-20 |
DE60122931T2 (en) | 2007-06-21 |
WO2002034774A2 (en) | 2002-05-02 |
ATE338820T1 (en) | 2006-09-15 |
HUP0302523A2 (en) | 2003-10-28 |
US20020151709A1 (en) | 2002-10-17 |
US7605304B2 (en) | 2009-10-20 |
US8188036B2 (en) | 2012-05-29 |
US20030177528A1 (en) | 2003-09-18 |
EP1356054A2 (en) | 2003-10-29 |
AU2002228705A1 (en) | 2002-05-06 |
CA2426793A1 (en) | 2002-05-02 |
EP1356054B1 (en) | 2006-09-06 |
MXPA03003666A (en) | 2005-01-25 |
HU228699B1 (en) | 2013-05-28 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8) C/C 13, 10, 18, 25 E 32 DA LPI. |
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B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
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B15K | Others concerning applications: alteration of classification |
Ipc: C07H 21/04 (2006.01), C12N 15/31 (2006.01), C07K 1 |