BR0110616A - Sequências de nucleotìdeos envolvidas no aumento ou diminuição da taxa de ovulação em mamìferos - Google Patents

Sequências de nucleotìdeos envolvidas no aumento ou diminuição da taxa de ovulação em mamìferos

Info

Publication number
BR0110616A
BR0110616A BR0110616-3A BR0110616A BR0110616A BR 0110616 A BR0110616 A BR 0110616A BR 0110616 A BR0110616 A BR 0110616A BR 0110616 A BR0110616 A BR 0110616A
Authority
BR
Brazil
Prior art keywords
mammals
increasing
ovulation rate
female
nucleotide sequences
Prior art date
Application number
BR0110616-3A
Other languages
English (en)
Inventor
George Henry Davis
Susan May Galloway
Kenneth Pattrick Mcnatty
Olli Visa-Pekka Ritvos
Original Assignee
Agres Ltd
Olli Visa-Pekka Ritvos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agres Ltd, Olli Visa-Pekka Ritvos filed Critical Agres Ltd
Publication of BR0110616A publication Critical patent/BR0110616A/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"SEQuêNCIAS DE NUCLEOTìDEOS ENVOLVIDAS NO AUMENTO OU DIMINUIçãO DA TAXA DE OVULAçãO EM MAMìFEROS". A presente invenção está relacionada a seq³ências de nucleotídeos que estão envolvidas no aumento ou diminuição da taxa de ovulação em mamíferos. Em particular, essa invenção diz respeito de forma ampla a novas mutações em um gene que está envolvido no aumento da taxa de ovulação em mamíferos fêmeas heterozigóticos; essas mutações causam esterilidade em mamíferos fêmea homozigóticos. O conhecimento da seq³ência de gene que sofreu mutação pode ser aplicado a um teste para identificar heterozigotos de mamíferos fêmeas e machos homozigóticos que carregam o gene que sofreu mutação. Esse conhecimento da função biológica do gene e de sua mutação pode ser também utilizado para aumentar ou diminuir a taxa de ovulação em mamíferos fêmea ou para induzir a esterilidade ou reduzir a fertilidade em mamíferos fêmea.
BR0110616-3A 2000-05-05 2001-05-04 Sequências de nucleotìdeos envolvidas no aumento ou diminuição da taxa de ovulação em mamìferos BR0110616A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ500844A NZ500844A (en) 2000-05-05 2000-05-05 Nucleotide sequences (mutated GDF-9B polypeptides) involved in increasing and decreasing mammalian ovulation rate
PCT/NZ2001/000073 WO2001085926A2 (en) 2000-05-05 2001-05-04 Nucleotide sequences involved in increasing or decreasing mammalian ovulation rate

Publications (1)

Publication Number Publication Date
BR0110616A true BR0110616A (pt) 2004-04-06

Family

ID=19927611

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110616-3A BR0110616A (pt) 2000-05-05 2001-05-04 Sequências de nucleotìdeos envolvidas no aumento ou diminuição da taxa de ovulação em mamìferos

Country Status (15)

Country Link
US (1) US20040092007A1 (pt)
EP (1) EP1292674B1 (pt)
JP (1) JP2003532414A (pt)
CN (1) CN1436237A (pt)
AR (1) AR028411A1 (pt)
AT (1) ATE401403T1 (pt)
AU (2) AU2001260821B2 (pt)
BR (1) BR0110616A (pt)
CA (1) CA2408051A1 (pt)
DE (1) DE60134852D1 (pt)
MX (1) MXPA02010868A (pt)
NZ (1) NZ500844A (pt)
RU (1) RU2283866C2 (pt)
WO (1) WO2001085926A2 (pt)
ZA (1) ZA200208963B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ502796A (en) * 2000-06-15 2003-02-28 Agres Ltd Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9
NZ519330A (en) * 2002-05-30 2004-12-24 George Henry Davis New sequences for altering mammalian ovarian function and ovulation rate
EP1819726A1 (en) * 2004-12-02 2007-08-22 Agresearch Limited Modulation of ovulation
EP1947195B1 (en) * 2005-09-13 2010-11-10 Neocodex, S.L. Method for the in vitro detection of a predisposition to the development of alterations in ovarian function
ES2338960B1 (es) * 2007-11-23 2011-04-19 Carnes Oviaragon S.C.L. Procedimiento de mejora de la productividad en ganado ovino.
CN105210981B (zh) * 2015-09-15 2018-09-28 中国科学院生物物理研究所 建立可应用于人类疾病研究的雪貂模型的方法及其应用
CN105941325A (zh) * 2016-06-17 2016-09-21 安徽省农业科学院畜牧兽医研究所 小尾寒羊母羊与澳洲白公羊杂交生产澳寒杂交母羊的方法
CN106614366A (zh) * 2016-12-29 2017-05-10 李振民 一种无抗生猪养殖方法
CN108753835A (zh) * 2018-05-30 2018-11-06 中山大学 一种利用CRISPR/Cas9编辑猪BMP15基因的方法
CN111500744A (zh) * 2020-04-27 2020-08-07 内蒙古大学 一种基于gdf9基因编码区突变的蒙古羊繁殖力提高方法
CN111440879A (zh) * 2020-04-27 2020-07-24 内蒙古大学 一种利用gdf9基因提高蒙古羊繁殖力的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635372A (en) * 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions

Also Published As

Publication number Publication date
CN1436237A (zh) 2003-08-13
AU2001260821B2 (en) 2006-04-13
US20040092007A1 (en) 2004-05-13
RU2283866C2 (ru) 2006-09-20
EP1292674A2 (en) 2003-03-19
WO2001085926A2 (en) 2001-11-15
MXPA02010868A (es) 2004-09-06
AU6082101A (en) 2001-11-20
NZ500844A (en) 2003-06-30
WO2001085926A3 (en) 2002-08-08
JP2003532414A (ja) 2003-11-05
CA2408051A1 (en) 2001-11-15
ATE401403T1 (de) 2008-08-15
EP1292674B1 (en) 2008-07-16
AR028411A1 (es) 2003-05-07
DE60134852D1 (de) 2008-08-28
ZA200208963B (en) 2004-07-26

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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