BR0109946A - Derivados de eritromicina substituìda em 6-o tendo tolerância gastrointestinal - Google Patents

Derivados de eritromicina substituìda em 6-o tendo tolerância gastrointestinal

Info

Publication number
BR0109946A
BR0109946A BR0109946-9A BR0109946A BR0109946A BR 0109946 A BR0109946 A BR 0109946A BR 0109946 A BR0109946 A BR 0109946A BR 0109946 A BR0109946 A BR 0109946A
Authority
BR
Brazil
Prior art keywords
erythromycin derivatives
gastrointestinal tolerance
compounds
substituted erythromycin
gastrointestinal
Prior art date
Application number
BR0109946-9A
Other languages
English (en)
Inventor
Zhenkun Ma
Ly Tam Phan
Richard F Clark
Souming Zhang
Stevan Djuric
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR0109946A publication Critical patent/BR0109946A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

"DERIVADOS DE ERITROMICINA SUBSTITUìDA EM 6-O TENDO TOLERâNCIA GASTROINTESTINAL". Os compostos tendo a fórmula (I) são úteis para o tratamento de infecções bacterianas, ao mesmo tempo evitando o risco concomitante de intolerância gastrointestinal. As composições contendo os compostos e os métodos de tratamento usando os compostos são também divulgados.
BR0109946-9A 2000-10-16 2001-10-16 Derivados de eritromicina substituìda em 6-o tendo tolerância gastrointestinal BR0109946A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24077700P 2000-10-16 2000-10-16
PCT/US2001/032278 WO2002032919A2 (en) 2000-10-16 2001-10-16 6-o-substituted erythromycin derivatives having improved gastrointestinal tolerance

Publications (1)

Publication Number Publication Date
BR0109946A true BR0109946A (pt) 2005-08-02

Family

ID=22907903

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109946-9A BR0109946A (pt) 2000-10-16 2001-10-16 Derivados de eritromicina substituìda em 6-o tendo tolerância gastrointestinal

Country Status (9)

Country Link
EP (1) EP1328534A2 (pt)
JP (1) JP2004529857A (pt)
AU (1) AU2002213267A1 (pt)
BR (1) BR0109946A (pt)
CA (1) CA2420012A1 (pt)
MX (1) MXPA03003311A (pt)
PE (1) PE20020522A1 (pt)
UY (1) UY26964A1 (pt)
WO (1) WO2002032919A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511752A (ja) 2001-12-05 2005-04-28 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 抗バクテリア剤として有効なエリスロマイシンの６−Ｏ−アシルケトーリド（ｋｅｔｏｌｉｄｅ）誘導体
EP1501845A1 (en) * 2002-04-30 2005-02-02 Abbott Laboratories Antibacterial compounds with improved pharmacokinetic profiles
US6727229B2 (en) * 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
WO2004078771A1 (ja) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. ２－フルオロ－６－ｏ－置換ケトライド誘導体
JP2007223900A (ja) * 2004-02-03 2007-09-06 Taisho Pharmaceut Co Ltd ６−ｏ−置換ケトライド誘導体
JP2007254285A (ja) * 2004-03-16 2007-10-04 Taisho Pharmaceut Co Ltd ２−フルオロ−６−ｏ−置換ケトライド誘導体
JP5015016B2 (ja) 2006-02-07 2012-08-29 大正製薬株式会社 １０ａ−アザライド化合物
US8293715B2 (en) 2007-08-06 2012-10-23 Taisho Pharmaceutical Co., Ltd. 10a-Azalide compound crosslinked at 10a- and 12-positions
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN102234302B (zh) * 2010-05-07 2014-05-07 北京理工大学 一种酮内酯衍生物、制备方法及其药物组合物
AR085286A1 (es) 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4
AR102810A1 (es) 2014-08-18 2017-03-29 Taisho Pharmaceutical Co Ltd Derivado de macrólido sustituido en la posición c-4

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity

Also Published As

Publication number Publication date
WO2002032919A3 (en) 2002-09-19
MXPA03003311A (es) 2003-09-10
AU2002213267A1 (en) 2002-04-29
JP2004529857A (ja) 2004-09-30
EP1328534A2 (en) 2003-07-23
UY26964A1 (es) 2002-06-20
PE20020522A1 (es) 2002-06-25
WO2002032919A2 (en) 2002-04-25
CA2420012A1 (en) 2002-04-25

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired