BR0109946A - 6-O-Substituted Erythromycin Derivatives Having Gastrointestinal Tolerance - Google Patents

6-O-Substituted Erythromycin Derivatives Having Gastrointestinal Tolerance

Info

Publication number
BR0109946A
BR0109946A BR0109946-9A BR0109946A BR0109946A BR 0109946 A BR0109946 A BR 0109946A BR 0109946 A BR0109946 A BR 0109946A BR 0109946 A BR0109946 A BR 0109946A
Authority
BR
Brazil
Prior art keywords
erythromycin derivatives
gastrointestinal tolerance
compounds
substituted erythromycin
gastrointestinal
Prior art date
Application number
BR0109946-9A
Other languages
Portuguese (pt)
Inventor
Zhenkun Ma
Ly Tam Phan
Richard F Clark
Souming Zhang
Stevan Djuric
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR0109946A publication Critical patent/BR0109946A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

"DERIVADOS DE ERITROMICINA SUBSTITUìDA EM 6-O TENDO TOLERâNCIA GASTROINTESTINAL". Os compostos tendo a fórmula (I) são úteis para o tratamento de infecções bacterianas, ao mesmo tempo evitando o risco concomitante de intolerância gastrointestinal. As composições contendo os compostos e os métodos de tratamento usando os compostos são também divulgados."ERYTHROMYCIN DERIVATIVES SUBSTITUTED IN 6-O HAVING GASTROINTESTINAL TOLERANCE". Compounds having formula (I) are useful for treating bacterial infections while avoiding the concomitant risk of gastrointestinal intolerance. Compositions containing the compounds and methods of treatment using the compounds are also disclosed.

BR0109946-9A 2000-10-16 2001-10-16 6-O-Substituted Erythromycin Derivatives Having Gastrointestinal Tolerance BR0109946A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24077700P 2000-10-16 2000-10-16
PCT/US2001/032278 WO2002032919A2 (en) 2000-10-16 2001-10-16 6-o-substituted erythromycin derivatives having improved gastrointestinal tolerance

Publications (1)

Publication Number Publication Date
BR0109946A true BR0109946A (en) 2005-08-02

Family

ID=22907903

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109946-9A BR0109946A (en) 2000-10-16 2001-10-16 6-O-Substituted Erythromycin Derivatives Having Gastrointestinal Tolerance

Country Status (9)

Country Link
EP (1) EP1328534A2 (en)
JP (1) JP2004529857A (en)
AU (1) AU2002213267A1 (en)
BR (1) BR0109946A (en)
CA (1) CA2420012A1 (en)
MX (1) MXPA03003311A (en)
PE (1) PE20020522A1 (en)
UY (1) UY26964A1 (en)
WO (1) WO2002032919A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ533282A (en) 2001-12-05 2006-09-29 Ortho Mcneil Pharm Inc 6-O-Acyl ketolide derivatives of erythromycine useful as antibacterials
MXPA04010802A (en) * 2002-04-30 2005-03-07 Abbott Lab Antibacterial compounds with improved pharmacokinetic profiles.
US6727229B2 (en) * 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
WO2004078771A1 (en) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. 2-fluoro-6-o-substituted ketolide derivative
JP2007223900A (en) * 2004-02-03 2007-09-06 Taisho Pharmaceut Co Ltd 6-o-substituted ketolide derivative
JP2007254285A (en) * 2004-03-16 2007-10-04 Taisho Pharmaceut Co Ltd 2-fluoro-6-o-substituted ketolide derivative
EP1985620A4 (en) 2006-02-07 2012-08-15 Taisho Pharmaceutical Co Ltd 10a-AZALIDE COMPOUND
JPWO2009019868A1 (en) 2007-08-06 2010-10-28 大正製薬株式会社 10a, 12-position cross-linked 10a-azalide compound
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN102234302B (en) * 2010-05-07 2014-05-07 北京理工大学 Novel ketolide derivatives, and preparation method and medicinal compositions thereof
AR085286A1 (en) 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd MACROLIDO DERIVATIVE REPLACED IN POSITION C-4
AR102810A1 (en) 2014-08-18 2017-03-29 Taisho Pharmaceutical Co Ltd MACROLID DERIVATIVE REPLACED IN POSITION C-4

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity

Also Published As

Publication number Publication date
JP2004529857A (en) 2004-09-30
MXPA03003311A (en) 2003-09-10
EP1328534A2 (en) 2003-07-23
PE20020522A1 (en) 2002-06-25
WO2002032919A2 (en) 2002-04-25
AU2002213267A1 (en) 2002-04-29
WO2002032919A3 (en) 2002-09-19
CA2420012A1 (en) 2002-04-25
UY26964A1 (en) 2002-06-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired