BR0108001A - Moléculas ativadoras de apc com ligação para cd-40 - Google Patents

Moléculas ativadoras de apc com ligação para cd-40

Info

Publication number
BR0108001A
BR0108001A BR0108001-6A BR0108001A BR0108001A BR 0108001 A BR0108001 A BR 0108001A BR 0108001 A BR0108001 A BR 0108001A BR 0108001 A BR0108001 A BR 0108001A
Authority
BR
Brazil
Prior art keywords
molecules
monoclonal antibodies
cells
present
professional
Prior art date
Application number
BR0108001-6A
Other languages
English (en)
Inventor
David Thomas
Mark De Boer
Pieter C J M Res
Peter J Simons
Original Assignee
Tanox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanox Inc filed Critical Tanox Inc
Publication of BR0108001A publication Critical patent/BR0108001A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Abstract

"MOLéCULAS ATIVADORAS DE APC COM LIGAçãO PARA CD-40". A presente invenção refere-se a moléculas agonistas anti-CD40, incluindo anticorpos monocionais, que podem se ligar e estimular células que apresentam antígeno humano profissional e não-profissional ("APCs"), aumentar o efeito estimulatório de células positivas CD40L em CD40 e ou induzir a maturação fenotípica de células dendríticas derivadas de monócitos. São fornecidos diversos anticorpos monocionais e as linhagens celulares produtoras dos mesmos foram depositadas na American Type Culture Collection.
BR0108001-6A 2000-02-01 2001-02-01 Moléculas ativadoras de apc com ligação para cd-40 BR0108001A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17893400P 2000-02-01 2000-02-01
PCT/US2001/003378 WO2001056603A1 (en) 2000-02-01 2001-02-01 Cd40-binding apc-activating molecules

Publications (1)

Publication Number Publication Date
BR0108001A true BR0108001A (pt) 2004-01-06

Family

ID=22654507

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0108001-6A BR0108001A (pt) 2000-02-01 2001-02-01 Moléculas ativadoras de apc com ligação para cd-40

Country Status (9)

Country Link
US (3) US7172759B2 (pt)
EP (2) EP1253942A4 (pt)
JP (1) JP2003524644A (pt)
CN (2) CN100490895C (pt)
AU (2) AU3662101A (pt)
BR (1) BR0108001A (pt)
CA (1) CA2398998C (pt)
MX (1) MXPA02007473A (pt)
WO (1) WO2001056603A1 (pt)

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Also Published As

Publication number Publication date
US20010026932A1 (en) 2001-10-04
CA2398998C (en) 2014-04-22
CN1443077A (zh) 2003-09-17
CN100490895C (zh) 2009-05-27
EP1253942A4 (en) 2004-06-16
EP1253942A1 (en) 2002-11-06
CN1942767A (zh) 2007-04-04
AU2001236621B2 (en) 2006-06-15
CA2398998A1 (en) 2001-08-09
JP2003524644A (ja) 2003-08-19
WO2001056603A1 (en) 2001-08-09
US20070098720A1 (en) 2007-05-03
US7172759B2 (en) 2007-02-06
AU3662101A (en) 2001-08-14
US20090311268A1 (en) 2009-12-17
EP1975182A1 (en) 2008-10-01
MXPA02007473A (es) 2003-09-22
US7820807B2 (en) 2010-10-26
US7547438B2 (en) 2009-06-16

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