BR0107483A - Processo para a preparação de um composto - Google Patents

Processo para a preparação de um composto

Info

Publication number
BR0107483A
BR0107483A BR0107483-0A BR0107483A BR0107483A BR 0107483 A BR0107483 A BR 0107483A BR 0107483 A BR0107483 A BR 0107483A BR 0107483 A BR0107483 A BR 0107483A
Authority
BR
Brazil
Prior art keywords
preparation
compound
disulfophenyl
butylhydroxylainonium
nterc
Prior art date
Application number
BR0107483-0A
Other languages
English (en)
Inventor
J Rgen Blixt
Henry Kruk
John Mcginley
Sergei Pouhov
John Vajda
Original Assignee
Astrazeneca Ab
Centaur Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Centaur Pharmaceuticals filed Critical Astrazeneca Ab
Publication of BR0107483A publication Critical patent/BR0107483A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids

Abstract

"PROCESSO PARA A PREPARAçãO DE UM COMPOSTO". Um processo para a preparação de <244>-(2,4-dissulfofenil)-Nterc-butilnitrona e seus sais farmaceuticamente aceitáveis pela reação do aldeído de dissulfofenila correspondente com acetato de N-terc-butilhidroxilainónio é apresentado.
BR0107483-0A 2000-01-10 2001-01-04 Processo para a preparação de um composto BR0107483A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0000055A SE0000055D0 (sv) 2000-01-10 2000-01-10 Novel process
PCT/SE2001/000007 WO2001051460A1 (en) 2000-01-10 2001-01-04 NOVEL PROCESS FOR THE PREPARATION OF α-(2-4-DISULFOPHENYL)-N-TERT-BUTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Publications (1)

Publication Number Publication Date
BR0107483A true BR0107483A (pt) 2002-09-03

Family

ID=20278055

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0107483-0A BR0107483A (pt) 2000-01-10 2001-01-04 Processo para a preparação de um composto

Country Status (32)

Country Link
US (1) US6479697B2 (pt)
EP (1) EP1265856B1 (pt)
JP (1) JP3748821B2 (pt)
KR (1) KR100687167B1 (pt)
CN (1) CN1198798C (pt)
AR (1) AR029431A1 (pt)
AT (1) ATE263753T1 (pt)
AU (1) AU783255B2 (pt)
BR (1) BR0107483A (pt)
CA (1) CA2395971A1 (pt)
CO (1) CO5280203A1 (pt)
DE (1) DE60102679T2 (pt)
DK (1) DK1265856T3 (pt)
EE (1) EE200200385A (pt)
ES (1) ES2217114T3 (pt)
HU (1) HU225298B1 (pt)
IL (2) IL150403A0 (pt)
IS (1) IS6456A (pt)
MX (1) MXPA02006674A (pt)
MY (1) MY122830A (pt)
NO (1) NO20023316D0 (pt)
NZ (1) NZ519828A (pt)
PL (1) PL357106A1 (pt)
PT (1) PT1265856E (pt)
RU (1) RU2259996C2 (pt)
SE (1) SE0000055D0 (pt)
SK (1) SK9932002A3 (pt)
TR (1) TR200401307T4 (pt)
TW (1) TW572880B (pt)
UA (1) UA71653C2 (pt)
WO (1) WO2001051460A1 (pt)
ZA (1) ZA200204872B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60320946D1 (de) 2002-02-14 2008-06-26 Willett Int Ltd Elektromagnetventil
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
EP1829668A1 (en) * 2004-12-01 2007-09-05 Toyo Boseki Kabushiki Kasisha Polyester resin film and process for producing the same
DK2399893T3 (en) 2004-12-22 2018-10-08 Ambrx Inc COMPOSITIONS CONTAINING, INVOLVING PROCEDURES, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES
WO2007013844A1 (en) * 2005-07-26 2007-02-01 Astrazeneca Ab Use of 4-[(tert-butylimino)benzene-1,3-disulfonate n-oxide against nausea
CN104622879A (zh) * 2008-02-12 2015-05-20 托斯克公司 减少毒性的多柔比星助剂及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437188A (fr) * 1964-06-17 1966-04-29 Du Pont Procédé de fabrication d'alpha-phényl-nu-méthyl nitrone
US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
SE9802507D0 (sv) * 1998-07-10 1998-07-10 Astra Ab Novel salts

Also Published As

Publication number Publication date
CN1395559A (zh) 2003-02-05
JP2003519678A (ja) 2003-06-24
EP1265856A1 (en) 2002-12-18
DE60102679T2 (de) 2004-12-09
NZ519828A (en) 2004-11-26
AU783255B2 (en) 2005-10-06
CN1198798C (zh) 2005-04-27
EP1265856B1 (en) 2004-04-07
TW572880B (en) 2004-01-21
ZA200204872B (en) 2003-10-07
US6479697B2 (en) 2002-11-12
MY122830A (en) 2006-05-31
CA2395971A1 (en) 2001-07-19
AR029431A1 (es) 2003-06-25
AU2720301A (en) 2001-07-24
HUP0204111A3 (en) 2005-05-30
ES2217114T3 (es) 2004-11-01
KR100687167B1 (ko) 2007-02-27
UA71653C2 (en) 2004-12-15
IL150403A0 (en) 2002-12-01
IL150403A (en) 2007-06-03
DK1265856T3 (da) 2004-07-05
DE60102679D1 (de) 2004-05-13
RU2259996C2 (ru) 2005-09-10
ATE263753T1 (de) 2004-04-15
SK9932002A3 (en) 2003-03-04
JP3748821B2 (ja) 2006-02-22
US20020128318A1 (en) 2002-09-12
PL357106A1 (en) 2004-07-12
HUP0204111A2 (hu) 2003-03-28
CO5280203A1 (es) 2003-05-30
MXPA02006674A (es) 2004-09-10
EE200200385A (et) 2003-12-15
WO2001051460A1 (en) 2001-07-19
NO20023316L (no) 2002-07-09
IS6456A (is) 2002-07-04
SE0000055D0 (sv) 2000-01-10
HU225298B1 (en) 2006-09-28
KR20020091077A (ko) 2002-12-05
RU2002118320A (ru) 2004-02-27
NO20023316D0 (no) 2002-07-09
PT1265856E (pt) 2004-07-30
TR200401307T4 (tr) 2004-07-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2012 DE 28/07/2009.