BR0015993A - Processes for preparing a collection of nucleic acids, a collection of recombinant vectors and a recombinant vector, detecting a nucleic acid and a polyketide synthase, identifying the production of a compound of interest, selecting a host cell recombinant, for producing a compound of interest and a polyketide synthase and for determining the diversity of nucleic acids contained in a collection, collection of nucleic acids, nucleic acid, vector, vector collection, recombinant host cell, collection of recombinant host cells , compound, polyketide, composition, polyketide synthase, antibody and polyketide synthase detection kit - Google Patents

Processes for preparing a collection of nucleic acids, a collection of recombinant vectors and a recombinant vector, detecting a nucleic acid and a polyketide synthase, identifying the production of a compound of interest, selecting a host cell recombinant, for producing a compound of interest and a polyketide synthase and for determining the diversity of nucleic acids contained in a collection, collection of nucleic acids, nucleic acid, vector, vector collection, recombinant host cell, collection of recombinant host cells , compound, polyketide, composition, polyketide synthase, antibody and polyketide synthase detection kit

Info

Publication number
BR0015993A
BR0015993A BR0015993-0A BR0015993A BR0015993A BR 0015993 A BR0015993 A BR 0015993A BR 0015993 A BR0015993 A BR 0015993A BR 0015993 A BR0015993 A BR 0015993A
Authority
BR
Brazil
Prior art keywords
collection
nucleic acids
recombinant
compound
vector
Prior art date
Application number
BR0015993-0A
Other languages
Portuguese (pt)
Inventor
Pascale Jeannin
Jean-Luc Pernodet
Michel Guerineau
Pascal Simonet
Sophie Courtois
Carmela Cappellano
Francois Francou
Alain Raynal
Maria Ball
Guennadi Sezonov
Karine Tuphile
Asa Frostegard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9915032A external-priority patent/FR2801609B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BR0015993A publication Critical patent/BR0015993A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"PROCESSOS DE PREPARAçãO DE UMA COLEçãO DE áCIDOS NUCLEICOS, DE UMA COLEçãO DE VETORES RECOMBINANTES E DE UM VETOR RECOMBINANTE, DE DETECçãO DE UM áCIDO NUCLEICO E DE UMA POLICETìDEO SINTASE, DE IDENTIFICAçãO DA PRODUçãO DE UM COMPOSTO DE INTERESSE, DE SELEçãO DE UMA CéLULA HOSPEDEIRA RECOMBINANTE, DE PRODUçãO DE UM COMPOSTO DE INTERESSE E DE UMA POLICETìDEO SINTASE E DE DETERMINAçãO DA DIVERSIDADE DE áCIDOS NUCLEICOS CONTIDOS EM UMA COLEçãO, COLEçãO DE áCIDOS NUCLEICOS, áCIDO NUCLEICO, VETOR, COLEçãO DE VETORES, CéLULA HOSPEDEIRA RECOMBINANTE, COLEçãO DE CéLULAS HOSPEDEIRAS RECOMBINANTES, COMPOSTO, POLICETìDEO, COMPOSIçãO, POLICETìDEO SINTASE, ANTICORPO E KIT DE DETECçãO DE UMA POLICETìDEO SINTASE". A presente invenção refere-se a um processo de preparação de ácidos nucleicos a partir de uma amostra do ambiente, mais particularmente um processo de obtenção de uma coleção de ácidos nucleicos a partir de uma amostra. A invenção também se refere aos ácidos nucleicos ou às coleções de ácidos nucleicos obtidos de acordo com o processo e sua aplicação na síntese de novos compostos, principalmente de novos compostos de interesse terapêutico. A invenção também tem por objeto os meios inéditos empregados no processo de obtenção de ácidos nucleicos acima, como vetores inéditos e processos inéditos de preparação de tais vetores ou, ainda, de células hospedeiras recombinantes compreendendo um ácido nucleico da invenção. A invenção refere-se também a processos para detectar um ácido nucleico de interesse dentro de uma coleção de ácidos nucleicos obtidos de acordo com o processo acima, bem como os ácidos nucleicos detectados por um tal processo e os polipeptídeos codificados por tais ácidos nucleicos"PROCESSES TO PREPARE A COLLECTION OF NUCLEIC ACIDS, A COLLECTION OF RECOMBINANT VECTORS AND A RECOMBINANT VECTOR, DETECTION OF A NUCLEIC ACID AND A SYNTHESIS POLICY, TO IDENTIFY THE PRODUCTION OF A PRODUCT, TO SELECT A PRODUCT FOR THE PRODUCTION RECOMBINANT HOST, FOR THE PRODUCTION OF A COMPOUND OF INTEREST AND A SYNTHESIS POLICETYDE AND DETERMINING THE DIVERSITY OF NUCLEIC ACIDS CONTAINED IN A COLLECTION, COLLECTION OF NUCLEIC ACID, NUCLEIC ACID, VECTOR, COLLECTOR, COLLECTOR, COLLECTOR, COLLECTOR, COLLECTOR RECOMBINANT, COMPOUND, POLYCETYDEO, COMPOSITION, POLYCETYDE SYNTHESIS, ANTIBODY AND DETECTION KIT FOR A POLYCETYDE SYNTHASE ". The present invention relates to a process for preparing nucleic acids from a sample of the environment, more particularly a process for obtaining a collection of nucleic acids from a sample. The invention also relates to nucleic acids or collections of nucleic acids obtained according to the process and their application in the synthesis of new compounds, mainly of new compounds of therapeutic interest. The invention also has as its object the unprecedented means employed in the process of obtaining nucleic acids above, such as unprecedented vectors and unprecedented processes for the preparation of such vectors or, still, of recombinant host cells comprising a nucleic acid of the invention. The invention also relates to processes for detecting a nucleic acid of interest within a collection of nucleic acids obtained according to the above process, as well as the nucleic acids detected by such a process and the polypeptides encoded by such nucleic acids

BR0015993-0A 1999-11-29 2000-11-27 Processes for preparing a collection of nucleic acids, a collection of recombinant vectors and a recombinant vector, detecting a nucleic acid and a polyketide synthase, identifying the production of a compound of interest, selecting a host cell recombinant, for producing a compound of interest and a polyketide synthase and for determining the diversity of nucleic acids contained in a collection, collection of nucleic acids, nucleic acid, vector, vector collection, recombinant host cell, collection of recombinant host cells , compound, polyketide, composition, polyketide synthase, antibody and polyketide synthase detection kit BR0015993A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9915032A FR2801609B1 (en) 1999-11-29 1999-11-29 PROCESS FOR OBTAINING NUCLEIC ACIDS FROM A SAMPLE OF THE ENVIRONMENT, NUCLEIC ACIDS THUS OBTAINED AND THEIR APPLICATION TO THE SYNTHESIS OF NEW COMPOUNDS
US20980000P 2000-06-07 2000-06-07
PCT/FR2000/003311 WO2001040497A2 (en) 1999-11-29 2000-11-27 Method for obtaining nucleic acids from an environment sample

Publications (1)

Publication Number Publication Date
BR0015993A true BR0015993A (en) 2002-08-06

Family

ID=26235170

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015993-0A BR0015993A (en) 1999-11-29 2000-11-27 Processes for preparing a collection of nucleic acids, a collection of recombinant vectors and a recombinant vector, detecting a nucleic acid and a polyketide synthase, identifying the production of a compound of interest, selecting a host cell recombinant, for producing a compound of interest and a polyketide synthase and for determining the diversity of nucleic acids contained in a collection, collection of nucleic acids, nucleic acid, vector, vector collection, recombinant host cell, collection of recombinant host cells , compound, polyketide, composition, polyketide synthase, antibody and polyketide synthase detection kit

Country Status (9)

Country Link
EP (1) EP1268764A2 (en)
JP (1) JP2003520578A (en)
KR (1) KR20020060242A (en)
AU (2) AU781961B2 (en)
BR (1) BR0015993A (en)
CA (1) CA2393041A1 (en)
IL (1) IL149846A0 (en)
NO (1) NO20022532L (en)
WO (1) WO2001040497A2 (en)

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US20040121311A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in livestock
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
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FR2834997B1 (en) * 2002-01-21 2004-03-19 Evialis METHOD FOR DETECTION OF OCHRATOXIN A OR CITRININ PRODUCING FUNGI
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EP1905833B1 (en) 2002-10-08 2015-08-12 Aventis Pharma S.A. Polypeptides involved in the biosynthesis of spiramycins, nucleotide sequences coding these polypeptides and their uses
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122096A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
JP4665124B2 (en) * 2004-01-28 2011-04-06 株式会社東京大学Ｔｌｏ Method for recovering DNA from environmental samples
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
ES2641832T3 (en) 2004-05-24 2017-11-14 Ibis Biosciences, Inc. Mass spectrometry with selective ion filtration by setting digital thresholds
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
EP1767621A4 (en) * 2004-06-08 2008-03-19 Toagosei Co Ltd Method of purifying environmental dna and method of efficiently screening protein-encoding gene from environmental dna
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
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Also Published As

Publication number Publication date
AU781961B2 (en) 2005-06-23
IL149846A0 (en) 2002-11-10
EP1268764A2 (en) 2003-01-02
CA2393041A1 (en) 2001-06-07
AU2005211587A1 (en) 2005-10-13
NO20022532D0 (en) 2002-05-28
KR20020060242A (en) 2002-07-16
NO20022532L (en) 2002-06-26
AU2179101A (en) 2001-06-12
JP2003520578A (en) 2003-07-08
WO2001040497A3 (en) 2002-10-17
WO2001040497A2 (en) 2001-06-07

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B15I Others concerning applications: loss of priority

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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