BR0012775A - Comprimido de microgrânulos com baixa dosagem de princìpio ativo contendo um diluente diretamente compressìvel, composição, e, processo de preparação do comprimido - Google Patents
Comprimido de microgrânulos com baixa dosagem de princìpio ativo contendo um diluente diretamente compressìvel, composição, e, processo de preparação do comprimidoInfo
- Publication number
- BR0012775A BR0012775A BR0012775-2A BR0012775A BR0012775A BR 0012775 A BR0012775 A BR 0012775A BR 0012775 A BR0012775 A BR 0012775A BR 0012775 A BR0012775 A BR 0012775A
- Authority
- BR
- Brazil
- Prior art keywords
- tablet
- directly compressible
- active ingredient
- composition
- preparation process
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPRIMIDO DE MICROGRâNULOS COM BAIXA DOSAGEM DE PRINCìPIO ATIVO CONTENDO UM DILUENTE DIRETAMENTE COMPRESSìVEL, COMPOSIçãO, E, PROCESSO DE PREPARAçãO DO COMPRIMIDO". A presente invenção refere-se a um comprimido de microgrânulos com baixa dosagem de princípio ativo contendo um diluente diretamente compressível, caracterizado pelo fato de que o diluente diretamente compressível é constituído exclusivamente de microgrânulos neutros, e pelo fato de que o princípio ativo está montado sobre os microgrânulos neutros e não é revestido com um agente destinado a modificar sua liberação ou a mascarar seu gosto.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9909653A FR2796840B1 (fr) | 1999-07-26 | 1999-07-26 | Comprimes faiblement doses et procede de preparation |
PCT/FR2000/002132 WO2001006982A2 (fr) | 1999-07-26 | 2000-07-25 | Comprimes faiblement doses et procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0012775A true BR0012775A (pt) | 2002-04-02 |
Family
ID=9548499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0012775-2A BR0012775A (pt) | 1999-07-26 | 2000-07-25 | Comprimido de microgrânulos com baixa dosagem de princìpio ativo contendo um diluente diretamente compressìvel, composição, e, processo de preparação do comprimido |
Country Status (29)
Country | Link |
---|---|
US (2) | US8337892B1 (pt) |
EP (1) | EP1200071B1 (pt) |
JP (1) | JP4812211B2 (pt) |
KR (1) | KR100649949B1 (pt) |
CN (1) | CN1172660C (pt) |
AT (1) | ATE236621T1 (pt) |
AU (1) | AU774801B2 (pt) |
BG (1) | BG65535B1 (pt) |
BR (1) | BR0012775A (pt) |
CA (1) | CA2391240C (pt) |
CZ (1) | CZ300238B6 (pt) |
DE (1) | DE60002089T2 (pt) |
DK (1) | DK1200071T3 (pt) |
DZ (1) | DZ3208A1 (pt) |
ES (1) | ES2191638T3 (pt) |
FR (1) | FR2796840B1 (pt) |
HR (1) | HRP20020165B1 (pt) |
HU (1) | HU228638B1 (pt) |
IL (2) | IL147682A0 (pt) |
MA (1) | MA25424A1 (pt) |
MX (1) | MXPA02000922A (pt) |
NO (1) | NO331905B1 (pt) |
NZ (1) | NZ516726A (pt) |
PL (1) | PL201215B1 (pt) |
PT (1) | PT1200071E (pt) |
SK (1) | SK285514B6 (pt) |
TR (1) | TR200200198T2 (pt) |
WO (1) | WO2001006982A2 (pt) |
ZA (1) | ZA200200380B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2852607B1 (fr) * | 2003-03-20 | 2006-07-14 | Procede de fabrication de microspheres de sucre de petite taille, les microspheres susceptibles d'etre obtenues par ce procede et leurs applications | |
FR2861990B1 (fr) * | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
WO2005123045A2 (en) * | 2004-06-10 | 2005-12-29 | Glatt Air Techniques, Inc. | Controlled release matrix pharmaceutical dosage formulation |
FR2883179B1 (fr) | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
FR2960775A1 (fr) | 2010-06-07 | 2011-12-09 | Ethypharm Sa | Microgranules resistants au detournement |
CN102416003A (zh) * | 2011-12-08 | 2012-04-18 | 南京优科生物医药有限公司 | 一种制备恩替卡韦片剂的方法 |
JP5897196B1 (ja) * | 2015-10-05 | 2016-03-30 | 大同化成工業株式会社 | 糖又は糖アルコール、膨潤型結合剤、崩壊剤及び高吸収性賦形剤を含む複合化造粒物及びその製造方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2996431A (en) * | 1953-12-16 | 1961-08-15 | Barry Richard Henry | Friable tablet and process for manufacturing same |
US3568828A (en) * | 1967-03-01 | 1971-03-09 | Squibb & Sons Inc | Modified sequential oral contraceptive |
US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
US4489026A (en) * | 1982-09-07 | 1984-12-18 | The Upjohn Company | Process for preparing solid unit dosage forms of ultra-low dose drugs |
US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
GB8414220D0 (en) * | 1984-06-04 | 1984-07-11 | Sterwin Ag | Medicaments in unit dose form |
WO1988002629A1 (en) * | 1986-10-16 | 1988-04-21 | American Health Products Corporation | 2',3'-didesoxyadenosine composition |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4925674A (en) * | 1988-08-25 | 1990-05-15 | Himedics, Inc. | Amoxicillin microencapsulated granules |
CA1338596C (en) * | 1988-09-27 | 1996-09-17 | Hiroyoshi Koyama | Granules having core and their production |
US4966770A (en) * | 1989-07-26 | 1990-10-30 | Himedics, Inc. | Prednisone microencapsulated granules |
US4983399A (en) * | 1989-10-18 | 1991-01-08 | Eastman Kodak Company | Direct compression carrier composition |
JP2820829B2 (ja) * | 1991-03-07 | 1998-11-05 | 武田薬品工業株式会社 | 有核散剤およびその製造方法 |
IE67345B1 (en) * | 1991-03-12 | 1996-03-20 | Akzo Nv | Low dose dry pharmaceutical preparations |
AR004178A1 (es) * | 1995-07-29 | 1998-11-04 | Smithkline Beecham Plc | Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma. |
SE9600046D0 (sv) * | 1996-01-05 | 1996-01-05 | Astra Ab | New pharmaceutical formulation |
GB9619074D0 (en) * | 1996-09-12 | 1996-10-23 | Smithkline Beecham Plc | Composition |
FR2816507B1 (fr) * | 2000-11-16 | 2003-02-28 | Ethypharm Lab Prod Ethiques | Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules |
-
1999
- 1999-07-26 FR FR9909653A patent/FR2796840B1/fr not_active Expired - Lifetime
-
2000
- 2000-07-25 AT AT00958607T patent/ATE236621T1/de active
- 2000-07-25 TR TR2002/00198T patent/TR200200198T2/xx unknown
- 2000-07-25 WO PCT/FR2000/002132 patent/WO2001006982A2/fr active IP Right Grant
- 2000-07-25 HU HU0202228A patent/HU228638B1/hu not_active IP Right Cessation
- 2000-07-25 PL PL353134A patent/PL201215B1/pl unknown
- 2000-07-25 MX MXPA02000922A patent/MXPA02000922A/es active IP Right Grant
- 2000-07-25 PT PT00958607T patent/PT1200071E/pt unknown
- 2000-07-25 IL IL14768200A patent/IL147682A0/xx active IP Right Grant
- 2000-07-25 CN CNB008120978A patent/CN1172660C/zh not_active Expired - Lifetime
- 2000-07-25 KR KR1020027001128A patent/KR100649949B1/ko active IP Right Grant
- 2000-07-25 ES ES00958607T patent/ES2191638T3/es not_active Expired - Lifetime
- 2000-07-25 SK SK93-2002A patent/SK285514B6/sk not_active IP Right Cessation
- 2000-07-25 NZ NZ516726A patent/NZ516726A/en not_active IP Right Cessation
- 2000-07-25 DZ DZ003208A patent/DZ3208A1/xx active
- 2000-07-25 JP JP2001511874A patent/JP4812211B2/ja not_active Expired - Lifetime
- 2000-07-25 DE DE60002089T patent/DE60002089T2/de not_active Expired - Lifetime
- 2000-07-25 AU AU70076/00A patent/AU774801B2/en not_active Expired
- 2000-07-25 DK DK00958607T patent/DK1200071T3/da active
- 2000-07-25 EP EP00958607A patent/EP1200071B1/fr not_active Expired - Lifetime
- 2000-07-25 BR BR0012775-2A patent/BR0012775A/pt not_active Application Discontinuation
- 2000-07-25 CA CA2391240A patent/CA2391240C/fr not_active Expired - Lifetime
- 2000-07-25 CZ CZ20020179A patent/CZ300238B6/cs not_active IP Right Cessation
- 2000-07-25 US US10/031,949 patent/US8337892B1/en not_active Expired - Fee Related
-
2002
- 2002-01-16 NO NO20020243A patent/NO331905B1/no not_active IP Right Cessation
- 2002-01-16 ZA ZA200200380A patent/ZA200200380B/en unknown
- 2002-01-17 IL IL147682A patent/IL147682A/en unknown
- 2002-01-18 MA MA26491A patent/MA25424A1/fr unknown
- 2002-01-23 BG BG106342A patent/BG65535B1/bg unknown
- 2002-02-25 HR HR20020165A patent/HRP20020165B1/xx not_active IP Right Cessation
-
2012
- 2012-08-16 US US13/587,629 patent/US20130039982A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2192226T3 (es) | Composicion farmaceutica oral que contiene agentes activos antimicrobianos y pantoprazol de liberacion prolongada. | |
BR9814924A (pt) | Microgrânulos de omeprazol, processo de preparação dos mesmos, e, preparações farmacêuticas | |
DE69323442D1 (de) | Flüssige pharmazeutische Formulierung mit verlängerter Wirkstoffabgabe | |
ES2171469T3 (es) | Composicion administrada por via nasal y preparacion que la contiene. | |
YU2494A (sh) | Farmaceutska formulacija za tretiranje zavisnosti od nikotina | |
BR0012775A (pt) | Comprimido de microgrânulos com baixa dosagem de princìpio ativo contendo um diluente diretamente compressìvel, composição, e, processo de preparação do comprimido | |
KR890015742A (ko) | 이병치료용 국소 제제 | |
ATE173627T1 (de) | Medizinische zusammensetzung | |
KR970032872A (ko) | 아세틸살리실산을 함유하는 피부 손상 처치용 약물 | |
DE59914183D1 (de) | Abgabeeinrichtung für eine zusammensetzung einer pharmazeutisch wirksamen substanz | |
GB2021409A (en) | Pharmaceutical composition | |
GEP20043377B (en) | Pharmaceutical Complex | |
KR910021238A (ko) | 켈로이드 치료제 | |
ATE233085T1 (de) | Arzneimittel zur topischen anwendung | |
ATE169818T1 (de) | Carbamazepin-arzneiform mit verzögerter wirkstofffreisetzung | |
ES2057053T3 (es) | Compuestos benzoheterociclicos. | |
EP0272393A3 (en) | Pharmaceutical combination | |
JPS5793913A (en) | Enhancing agent for spermous vital power | |
BR0115206A (pt) | Composições hidroliticamente instáveis | |
KR900018051A (ko) | 트리아졸 화합물, 이를 함유하는 항진균제 및 이를 사용한 만성 진균증의 예방 및/또는 치료법 | |
MX9302986A (es) | Medicamento que contiene metrifonato y procedimiento para su preparacion | |
MA21895A1 (fr) | Association de vitamine "a" a dose physiologique et differents principes actifs . | |
KR960003717A (ko) | 항암제에 의해 유발되는 말초신경병의 예방에 유용한 의약의 제조를 위한 엘리프로딜 및 그 거울상이성질체의 이용 | |
BR9912260A (pt) | Emplastro contendo um sistema terapêutico transdérmico e dose única para ministração | |
KR920019349A (ko) | 불안을 치료하기 위한 r(+)-3-아미노-1-하이드록시-피롤리딘-2-온의 용도 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11 E 13 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |