BR0012748A - Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino - Google Patents

Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino

Info

Publication number
BR0012748A
BR0012748A BR0012748-5A BR0012748A BR0012748A BR 0012748 A BR0012748 A BR 0012748A BR 0012748 A BR0012748 A BR 0012748A BR 0012748 A BR0012748 A BR 0012748A
Authority
BR
Brazil
Prior art keywords
growth
hormone
growth hormone
animal
analog
Prior art date
Application number
BR0012748-5A
Other languages
English (en)
Inventor
Robert J Schwartz
Ruxandra Draghia-Akli
Original Assignee
Baylor College Of Medcine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Of Medcine filed Critical Baylor College Of Medcine
Publication of BR0012748A publication Critical patent/BR0012748A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Feed For Specific Animals (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)

Abstract

"ANáLOGO SUPER-ATIVO DO HORMÈNIO DE LIBERAçãO DO HORMÈNIO DO CRESCIMENTO PORCINO". Crescimento inadequado devido a deficiências no hormónio do crescimento (GR) , no hormónio de liberação do hormónio do crescimento (GHRH) ou devido a doenças genéticas pode ser melhorado utilizando terapia com proteina recombinante com um GHRH análogo novo apresentando uma seq³ência da SEQ ID NO:1). Também está incluído: (1) um método de tratamento das deficiências relacionadas ao hormónio de crescimento associado com a via do hormónio do crescimento; (2) um método para tratamento das deficiências relacionadas ao hormónio do crescimento associado com doenças genéticas; (3) um método para melhorar o desempenho do crescimento em um animal; (4) um método para tratamento de um animal com uma doença de deficiência de crescimento; (5) um método para aumentar a eficiência de um animal utilizado para consumo; e (6) um método para intensificar o crescimento em um animal.
BR0012748-5A 1999-07-26 2000-07-24 Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino BR0012748A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14562499P 1999-07-26 1999-07-26
PCT/US2000/020127 WO2001006988A2 (en) 1999-07-26 2000-07-24 Super-active porcine growth hormone releasing hormone analog

Publications (1)

Publication Number Publication Date
BR0012748A true BR0012748A (pt) 2003-06-10

Family

ID=22513900

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012748-5A BR0012748A (pt) 1999-07-26 2000-07-24 Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino

Country Status (13)

Country Link
US (3) US6551996B1 (pt)
EP (1) EP1204321B1 (pt)
JP (1) JP4644402B2 (pt)
KR (1) KR20020047096A (pt)
CN (1) CN1635898A (pt)
AT (1) ATE309358T1 (pt)
AU (1) AU772752B2 (pt)
BR (1) BR0012748A (pt)
CA (1) CA2378943C (pt)
DE (1) DE60023906T2 (pt)
MX (1) MXPA02000938A (pt)
PL (1) PL366132A1 (pt)
WO (1) WO2001006988A2 (pt)

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AR035671A1 (es) * 2000-12-12 2004-06-23 Advisys Inc Administracion de secuencia de acido nucleico a un animal hembra, para aumentar el crecimiento de la descendencia
US20030157717A1 (en) * 2001-09-07 2003-08-21 Baylor College Of Medicine Texas Medical Center Linear DNA fragments for gene expression
MXPA04003944A (es) * 2001-10-26 2004-07-08 Baylor College Medicine Una composicion y metodo para alterar la masa corporal fina y propiedades oseas en un sujeto.
AU2002357143B2 (en) 2001-12-11 2009-07-30 Advisys, Inc. Growth hormone releasing hormone supplementation for treating chronically ill subjects
MXPA04007638A (es) * 2002-02-07 2004-12-06 Baylor College Medicine Desarrollo modificado de la glandula pituitaria en productos de madres animales prenadas, tratadas con terapia de hormona liberadora de hormona del crecimiento.
MXPA04011766A (es) * 2002-05-28 2005-03-31 Advisys Inc SUMINISTRO AUMENTADO DE UNA CONSTRUCCION DE áCIDO NUCLEICO IN VIVO POR EL SISTEMA DE POLO-L-GLUTAMATO (PLG).
WO2004007678A2 (en) * 2002-07-16 2004-01-22 Advisys, Inc. Codon optimized synthetic plasmids
US20060128615A1 (en) * 2002-09-18 2006-06-15 Pierrette Gaudreau Ghrh analogues
WO2004067719A2 (en) * 2003-01-28 2004-08-12 Advisys, Inc. Growth hormone releasing hormone (ghrh) for use in reducing culling in herd animals
US7361642B2 (en) * 2003-08-04 2008-04-22 Vgx Pharmaceuticals, Inc. Canine specific growth hormone releasing hormone
US7442673B2 (en) * 2003-08-15 2008-10-28 Crompton Corporation Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives
WO2005065722A2 (en) * 2003-12-31 2005-07-21 Advisys, Inc. Reducing arthritis and lameness in subjects by growth hormone releasing hormone (ghrh) supplementation
US20090005333A1 (en) * 2004-01-26 2009-01-01 Vgx Pharmaceuticlas, Inc. Reducing culling in herd animals growth hormone releasing hormone (ghrh)
US7846720B2 (en) * 2005-01-26 2010-12-07 Vgx Pharmaceuticals, Inc. Optimized high yield synthetic plasmids
JP5649825B2 (ja) 2007-01-31 2015-01-07 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 安定化させたp53ペプチドおよびその使用法
KR20160061439A (ko) 2007-03-28 2016-05-31 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
US8226468B2 (en) * 2008-11-13 2012-07-24 Igt Gaming system and method including points of symbol expansion
US20100267636A1 (en) * 2009-04-20 2010-10-21 Theratechnologies Inc. Use of cytochrome p450-metabolized drugs and grf molecules in combination therapy
US20100267635A1 (en) * 2009-04-20 2010-10-21 Theratechonolgies Inc. Use of protease inhibitors and grf molecules in combination therapy
KR102104762B1 (ko) 2010-08-13 2020-04-24 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
KR20140100937A (ko) 2011-10-18 2014-08-18 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
CN102516364B (zh) * 2011-12-26 2013-11-06 吉林农业大学 一种模拟猪生长激素样的活性肽及制备方法与应用
CN104144695A (zh) 2012-02-15 2014-11-12 爱勒让治疗公司 ***交联的和硫醚交联的拟肽大环化合物
CN107216380A (zh) 2012-02-15 2017-09-29 爱勒让治疗公司 拟肽大环化合物
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
KR20150082307A (ko) 2012-11-01 2015-07-15 에일러론 테라퓨틱스 인코포레이티드 이치환 아미노산 및 이의 제조 및 사용 방법
BR112017005598A2 (pt) 2014-09-24 2017-12-12 Aileron Therapeutics Inc macrociclos peptidomiméticos e usos dos mesmos
EP3294318A4 (en) 2015-03-20 2019-04-03 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
JP7134093B2 (ja) 2016-04-19 2022-09-09 グリフォン・ファーマシューティカルズ・アンテルナシオナル・エスアー ペグ化バイオアクティブペプチド及びその使用
CN112724260B (zh) * 2021-01-15 2021-11-30 安徽中起生物科技有限公司 一种脂质体包封的重组兽用促生长蛋白及其制备方法和应用
CN113582881B (zh) * 2021-07-29 2022-10-11 浙江新码生物医药有限公司 一种非天然氨基酸及其应用、包含其的重组蛋白以及重组蛋白偶联物

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Also Published As

Publication number Publication date
CN1635898A (zh) 2005-07-06
CA2378943A1 (en) 2001-02-01
MXPA02000938A (es) 2004-03-19
WO2001006988A2 (en) 2001-02-01
DE60023906T2 (de) 2006-07-20
DE60023906D1 (de) 2005-12-15
PL366132A1 (en) 2005-01-24
CA2378943C (en) 2012-09-18
ATE309358T1 (de) 2005-11-15
US20030129172A1 (en) 2003-07-10
WO2001006988A3 (en) 2001-08-09
US7166461B2 (en) 2007-01-23
JP4644402B2 (ja) 2011-03-02
US6551996B1 (en) 2003-04-22
AU772752B2 (en) 2004-05-06
KR20020047096A (ko) 2002-06-21
EP1204321B1 (en) 2005-11-09
US20030148948A1 (en) 2003-08-07
EP1204321A2 (en) 2002-05-15
EP1204321A4 (en) 2002-11-06
JP2003517294A (ja) 2003-05-27
AU6607800A (en) 2001-02-13

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT. CL. A01N 43/04, A61K 31/70, C12N 5/00, C12N 5/02, C12N 15/00, C12N 15/09, C12N 15/63, C12N 15/70, C12N 15/74 C12N 15/85, C12N 15/87, C07H 21/02, C07H 21/04.

Ipc: A61K 38/18 (2006.01), A61K 48/00 (2006.01), C12N 1

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2138 DE 27/12/2011.